Now showing items 737-756 of 2801

    • Riquelme, Jaime; Westermeier, Francisco; Hall, Andrew R.; Vicencio, Jose; Pedrozo Cibils, Zully; Ibacache, Mauricio; Fuenzalida, Barbara; Sobrevia, Luis; Davidson, Sean M.; Yellon, Derek M.; Sánchez, Gina; Lavandero González, Sergio (Elsevier, 2016)
      The alpha2-adrenergic receptor agonist Dexmedetomidine (Dex) is a sedative medication used by anesthesiologists. Dex protects the heart against ischemia-reperfusion (IR) and can also act as a preconditioning mimetic. The ...
    • Carmona, Danilo J.; Jaque-Olmedo, Pablo; Vöhringer Martínez, Esteban (Springer, 2020)
      Peroxides play a central role in many chemical and biological processes such as the Fenton reaction. The relevance of these compounds lies in the low stability of the O-O bond which upon dissociation results in radical ...
    • Villar, Eugenia del; Vega, Patricio; Gaule, Carlos; Sanchez, Emilio (1990)
      Short or long term diabetes in female rats produced remarkable activation of aminopyrine N-demethylation, inhibition of oestrone and p-nitrophenol glucuronidation and no changes in morphine UDP-glucuronyltransferase activity ...
    • Battiprolu, Pavan K.; López Crisosto, Camila; Wang, Zhao V.; Nemchenko, Andriy; Lavandero González, Sergio; Hill, Joseph A. (2013)
      The incidence and prevalence of diabetes mellitus are both increasing rapidly in societies around the globe. The majority of patients with diabetes succumb ultimately to heart disease, much of which stems from atherosclerotic ...
    • Yempala, Thirumal; Brea, José; Loza, María Isabel; Matthies, Douglas; Zapata Torres, Gerald; Cassels Niven, Bruce (American Chemical Society, 2020)
      The human 5-HT2 receptor subtypes have high sequence identity in their orthosteric ligand-binding domain, and many agonists are poorly selective between the S-HT(2A )and 5-HT2C subtypes. Nevertheless, their activation is ...
    • Garland, María Teresa; Manzur Saffie, Jorge; Moreno N., Yanko; Spodine Spiridonova, Evgenia; Baggio, Ricardo; González, Oscar (MUNKSGAARD INT PUBL LTD, 1996-06-15)
      The title complex, [CuBr2(C12H11N3)], is a monomer and the environment around the Cu2+ ion is that of a square pyramid, with one Br- ion occupying the apical site and the other Br- ion at a basal position.
    • Atria Salas, Ana María; Baggio, Ricardo; Espinosa, N.; Garland, María Teresa; Manzur Saffie, Jorge; Moreno N., Yanko; Spodine Spiridonova, Evgenia (Munksgaard Int. Publ. Ttd., 1994-07-15)
      The crystal structures of dichloro- (2) and dibromo[2-pyridilmethylidene)-2thienylmethylidene)-2-thienylmethylmethyamine-NN'] copper(II) (1) have been determined to investigate the coordination of die metal centre. In ...
    • García, A. M.; Manzur Saffie, Jorge; Spodine Spiridonova, Evgenia; Baggio, Ricardo; Garland, María Teresa (MUNKSGAARD INT PUBL LTD, 1994-12-15)
      The crystal structure of [CUCl2(C12H12N2)] is reported. The complex is monomeric, with the Cu atom coordinated to two N atoms and two Cl- ions. The compound displays simple paramagnetic behaviour.
    • Ortiz Viedma, Jaime; Romero, Nalda; Robert Canales, Paz; Araya, Juan Carlos; López Hernández, J.; Bozzo, C.; Navarrete, E.; Osorio, A.; Ríos, A. (ELSEVIER, 2006)
      The nutritional composition of the edible seaweeds Durvillaea antaretica (frond and stem) and dried Ulva lactuca was determined, including the soluble (SDF), insoluble (IDF) and total (TDF) dietary fiber content, amino ...
    • Fritsch Montero, Rosemarie; Escanilla Durán, Ximena; Goldsack Zambrano, Victoria; Grinberg, Amalia; Navarrete, Araceli; Pérez, Alejandra; Rivera, Caterine; González, Isabel; Sepúlveda, Rodrigo Enrique; Rojas Castillo, María Graciela (Universidad de Chile, Facultad de Medicina, Clínica Psiquiátrica Universitaria, 2006)
      Existen numerosos estudios que muestran que los trastornos mentales comunes son enfermedades frecuentes y discapacitantes. Se ha observado que los estudiantes universitarios constituyen un grupo de riesgo. El objetivo ...
    • Noriega Sepúlveda, Viviana Carolina; Pennanen Saavedra, Christian; Llancaqueo Valeri, Marcelo; Lavandero González, Sergio; Prieto Domínguez, Juan (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2007)
      Las estatinas son fármacos de elección para el tratamiento de hipercolesterolemia. Sin embargo, dado que existe una considerable variabilidad interindividual en la reducción del colesterol, la evaluación farmacogenética ...
    • Espinosa, Victoria; Kettlun, Ana María; Zanocco Loyola, Antonio; Cardemil, E.; Valenzuela, A. M. (PERGAMON-ELSEVIER SCIENCE LTD, 2003-05)
      Comparative studies of intrinsic and extrinsic fluorescence of apyrases purified from two potato tuber varieties (Pimpernel and Desiree) were performed to determine differences in the microenvironment of the nucleotide ...
    • Castãeda, Fernando; Jullian Matthaei, Carolina; Bunton, Clifford A.; Garland, María Teresa; Baggio, Ricardo (2007)
      Hydrogen bonding and crystal packing play major roles in determining the conformations of ethyl methyl 2-(triphenyl-phospho-ranyl-idene)malonate, Ph3P=C(CO2CH3)CO2CH2CH3 or C24H23O4P, (I), and dimethyl 2-(triphenyl-phosphor- ...
    • Castañeda Magliona, Fernando; Jullian Matthaei, Carolina; Bunton, Clifford A.; Garland, María Teresa; Baggio, Ricardo (International Union of Crystallography, 2007)
      Hydrogen bonding and crystal packing play major roles in determining the conformations of ethyl methyl 2-(triphenyl-phosphoranylidene)malonate, Ph3P=C(C02CH3)CO2CH2CH3 or C24H23O4P,(I), and dimethyl 2-(triphenylphosphora ...
    • Campos, Rolando; Maureira, Francisco; Garrido, Argelia; Valenzuela Bonomo, Carlos (1993)
      When the rat kidney is subjected to ischemia and reperfusion, changes in glutathione content and in lipid peroxidation are produced in the cortex and in the medulla. The cortex shows a decrease in the glutathione content ...
    • Bravo, Denisse; Hoare, Anilei; Silipo, Alba; Valenzuela, Camila; Salinas, Catalina; Álvarez Armijo, Sergio Aníbal; Molinaro, Antonio; Valvano, Miguel A.; Contreras, Inés (Elsevier, 2011)
      The role of lipopolysaccharide (LPS) in entry of Salmonella Typhimurium into epithelial cells remains unclear. In this study, we tested the ability of a series of mutants with deletions in genes for the synthesis and ...
    • Valenzuela,; Guerra, (Birkhäuser-Verlag, 1986)
      We have observed a differential effect of silybin dihemisuccinate on rat liver microsonal oxygen consumption and on lipid peroxidation induced by NADPH-Fe2+-ADP and t-butyl hydroperoxide. These results are ascribed to the ...
    • Eynaudi Cáceres, Andrea Patricia; Díaz Castro, Francisco; Bórquez, Juan Carlos; Bravo Sagua, Roberto Francisco; Parra Ortiz, Valentina María; Troncoso Cotal, Rodrigo Hernán (Frontiers Media, 2021)
      Fatty acid overload, either of the saturated palmitic acid (PA) or the unsaturated oleic acid (OA), causes triglyceride accumulation into specialized organelles termed lipid droplets (LD). However, only PA overload leads ...
    • Brüning, M.; Aylwin, C.; Díaz Alvarado, Felipe Andrés (Elsevier, 2015)
    • Weiss López, Boris; Azócar Rangel, Mauricio Alejandro; Montecinos, R.; Cassels Niven, Bruce; Araya Maturana, Ramiro (AMER CHEMICAL SOC, 2001-10-30)
      Deuterium quadrupole splittings from two series of optical isomers, L- and D-N-acyl-l-phenyl-d(5)-2-aminopropane, with linear acyl chains ranging from I to 10 carbon atoms, were measured using H-2 NMR spectroscopy. Both ...