Browsing by Title Artículos de revistas

Now showing items 1411-1430 of 2801

    • Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression 
      Morales, Cyndi R.; Li, Dan L.; Pedrozo Cibils, Zully; May, Herman I.; Jiang, Nan; Kyrychenko, Viktoriia; Cho, Geoffrey; Kim, Soo Young; Wang, Zhao V.; Rotter, David; Rothermel, Beverly A.; Schneider, Jay W.; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Amer Assoc Advancement Science, 2016)
      Altering chromatin structure through histone posttranslational modifications has emerged as a key driver of transcriptional responses in cells. Modulation of these transcriptional responses by pharmacological inhibition ...
    • Inhibition of cytosolic glutathione S-transferase activity from rat liver by copper 
      Letelier Muñoz, María Eugenia; Martínez, M.; González Lira, Víctor; Faúndez, Mario; Aracena Parks, Paula (ELSEVIER, 2006-12-01)
      H2O2 inactivation of particular GST isoforms has been reported, with no information regarding the overall effect of other ROS on cytosolic GST activity. The present work describes the inactivation of total cytosolic GST ...
    • Inhibition of HIV-2(ROD) replication in a lymphoblastoid cell line by the alpha 1-antitrypsin Portland ... 
      Bahbouhi, B.; Bendjennat, M.; Chiva, C.; Kogan Bocian, Marcelo; Albericio, F.; Giralt, Ernest; Seidah, N. G.; Bahraoui, E. (EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2001-11)
      We investigated the effects of alpha1-antitrypsine Portland variant (alpha1-PDX) and decanoylRVKRchloromethylketone (decRVKRcmk) on HIV-2(ROD) replication in the Jurkat lymphoblastoid cell line. To this end, cells were ...
    • Inhibition of soybean 15-lipoxygenase and human 5-lipoxygenase by extracts of leaves, stem bark, phenols ... 
      Muñoz Ramírez, Alejandra; Mascayano Collado, Carolina; Barriga, Andrés; Echeverría, Javier; Urzúa, Alejandro (Frontiers Media, 2020)
      Lithraea caustica (Molina) Hook. and Arn. (Anacardiaceae), common name Litre, is an evergreen endemic plant used in the Mapuche Chilean folk medicine. The stem juice of L. caustica mixed with Rubus ulmifolius (blackberry) ...
    • Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by ... 
      Ponnappa, Biddanda C.; Israel Jacard, Yedy; Aini, María; Zhou, Feng; Russ, Rachel; Cao, Qing-na; Yiyang, Hu; Rubin, Raphael (PERGAMON-ELSEVIER SCIENCE LTD, 2005-02-15)
      Elevated serum tumor necrosis factor alpha JNF-alpha) levels predict mortality in patients with alcoholic liver disease. Administration of anti-TNF-alpha antibodies, obliteration of Kupffer cells or gut sterilization protect ...
    • Inhibition of tumoral cell respiration and growth by nordihydroguaiaretic acid 
      Pavani, M.; Fones, Elizabeth; Oksenberg Reisberg, Danny; García, Manuel; Hernández, Carolina; Cordano, Gianni; Muñoz, Sergio; Mancilla, Jerson; Guerrero, Aanibal; Ferreira Parker, Jorge (PERGAMON-ELSEVIER SCIENCE LTD, 1994-11-16)
      The effects of nordihydroguaiaretic acid (NDGA), best known as an inhibitor of lipoxygenase activities, on the culture growth, oxygen consumption, ATP level, viability, and redox state of some electron carriers of intact ...
    • Inhibitory effect of vanillin-like compounds on respiration and growth of adenocarcinoma TA3 and its ... 
      Cordano, G.; Pezoa Olivares, Jacqueline; Muñoz, S.; Rivera, E.; Medina, Jorge; Núñez Vergara, Luis; Pavani, Mario; Guerrero A., Aníbal; Ferreira Parker, Jorge (ELSEVIER SCIENCE BV, 2002-09)
      The effects of some imine and amine derivatives of vanillin on the respiration rate of mouse mammary adenocarcinoma TA3 line, its multiresistant variant TA3-MTX-R line and mouse hepatocytes, together with their respective ...
    • Inkjet Printing of Proteins: an Experimental Approach 
      Montenegro-Nicolini, Miguel; Miranda, Víctor; Morales, Javier O. (Springer New York LLC, 2017)
      © 2016, American Association of Pharmaceutical Scientists. Peptides and proteins represent a promissory group of molecules used by the pharmaceutical industry for drug therapy with great potential for development. However, ...
    • An Inositol 1,4,5-Triphosphate (IP3)-IP3 Receptor Pathway Is Required for Insulin-Stimulated Glucose ... 
      Contreras Ferrat, Ariel Eduardo; Toro, Barbra; Bravo, R.; Parra Ortíz, María Valentina; Vásquez, C.; Ibarra, Cristián; Mears, David; Chiong Lay, Mario; Jaimovich Pérez, Enrique; Klip, Amira; Lavandero González, Sergio (ENDOCRINE SOC, 2010-10)
      Intracellular calcium levels ([Ca2+](i)) and glucose uptake are central to cardiomyocyte physiology, yet connections between them have not been studied. We investigated whether insulin regulates [Ca2+](i) in cultured ...
    • The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1 
      Vicencio, José Miguel; Ortíz, C.; Criollo Céspedes, Alfredo; Jones, A. W. E.; Kepp, O.; Galluzzi, Lorenzo; Joza, N.; Vitale, I.; Morselli, E.; Tailler, M.; Castedo, M.; Maiuri, M. C.; Molgó, Jordi; Szabadkai, G.; Lavandero González, Sergio; Kroemer, Guido (NATURE PUBLISHING GROUP, 2009-07)
      The inositol 1,4,5-trisphosphate receptor (IP3R) is a major regulator of apoptotic signaling. Through interactions with members of the Bcl-2 family of proteins, it drives calcium (Ca2+) transients from the endoplasmic ...
    • The inositol trisphosphate receptor in the control of autophagy 
      Criollo Céspedes, Alfredo; Vicencio, José Miguel; Tasdemir, E.; Maiuri, M. C.; Lavandero González, Sergio; Kroemer, Guido (LANDES BIOSCIENCE, 2007-07)
      The second messenger myo-inositol-1,4,5-trisphosphate (IP3) acts on the IP3 receptor (IP3R), an IP3-activated Ca2+ channel of the endoplasmic reticulum (ER). The IP3R agonist IP3 inhibits starvation-induced autophagy. The ...
    • Insights into the HyPer biosensor as molecular tool for monitoring cellular antioxidant capacity 
      Hernández, Helen; Parra, Alejandra; Tobar, Nicolas; Molina, Jessica; Kallens, Violeta; Hidalgo, Miltha; Varela, Diego; Martínez, Jorge; Porras Espinoza, Omar (Elsevier B.V., 2018)
      © 2018 The Authors Aerobic metabolism brings inexorably the production of reactive oxygen species (ROS), which are counterbalanced by intrinsic antioxidant defenses avoiding deleterious intracellular effects. Redox balance ...
    • Insights of the formation mechanism of nanostructured titanium oxide polymorphs from different macromolecular ... 
      Allende, Patricio; Orera, Alodia; Laguna Bercero, Miguel A.; Valenzuela, María Luisa; Díaz, Carlos; Barrientos, Lorena (Elsevier, 2021)
      The insight into the mechanism of the unprecedented formation of pure anatase TiO2 from the macromolecular (Chitosan)center dot(TiOSO4)(n) precursor has been investigated using micro Raman spectroscopy, Scanning Electron ...
    • Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus 
      Westermeier, Francisco; Sáez, T.; Arroyo, P.; Toledo, F.; Gutiérrez, J.; Sanhueza, C.; Pardo, F.; Leiva, A.; Sobrevia, L. (Wiley-Blackwell, 2016)
      The human insulin receptor (IR) exists in two isoforms that differ by the absence (IR-A) or the presence (IR-B) of a 12-amino acid segment encoded by exon 11. Both isoforms are functionally distinct regarding their binding ...
    • Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced ... 
      Westermeier, Francisco; Salomón, Carlos; Farías, Marcelo; Arroyo, Pablo; Fuenzalida, Bárbara; Sáez, Tamara; Salsoso, Rocío; Sanhueza, Carlos; Guzmán Gutiérrez, Enrique; Pardo, Fabián; Leiva, Andrea; Sobrevia, Luis (2015)
      Reduced adenosine uptake via human equilibrative nucleoside transporter 1 (hENT1) in human umbilical vein endothelial cells (HUVECs) from gestational diabetes mellitus (GDM) is reversed by insulin by restoring hENT1 ...
    • Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death 
      Díaz, Ariel; Humeres, Claudio; González, Verónica; Gómez, María Teresa; Montt, Natalia; Sánchez, Gina; Chiong Lay, Mario; García Nannig, Lorena (Academic Press Inc., 2015)
      In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death. However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective action ...
    • INTEGRATED FIA HPLC METHOD FOR PRECONCENTRATION AND DETERMINATION OF TRANSITION-METAL IONS 
      Fernández Romero, J. M.; De Castro, M. D. L.; Richter Duk, Pablo; Valcarcel, Miguel (FRIEDR VIEWEG SOHN VERLAG GMBH, 1992-11)
      An automatic method based on the combination of a flow injection (FI) manifold with a liquid chromatograph has been developed for the enrichment and determination of transition metal ions in water samples. Alternatively, ...
    • Integrated Pressurized Solvent Extraction-Cleanup for the Rapid Determination of Polychlorinated Biphenyls ... 
      Toledo Neira, Carla; Enríquez, Pedro; Richter Duk, Pablo (Sociedade Brasileira de Química, 2013)
      A rapid and efficient method based on the integration of pressurized solvent extraction (PSE) with solid phase extraction (SPE) cleanup and gas chromatography system with electron capture detection (GC-ECD) has been developed ...
    • Integrated retention/spectrophotometric detection method for the determination of formaldehyde 
      Richter Duk, Pablo; Luque de Castro, M.; Valcárcel, Miguel (1992)
      An integrated-sensor method for the determination of formaldehyde based on retention of the reaction product of the analyte with p-rosaniline and sulfite in a flow-cell packed with Dowex 1-X-8 anion exchange resin was ...
    • Integrated sulfate reduction and biosorption process for the treatment of mine drainages 
      Cotoras, Davor; Hurtado, Cristian; Viedma, Pabla (Trans Tech, 2017)
      Sulfate is a pollutant present in the mining waste water and acid mine drainage. High levels of sulfate can generate important environmental problems. One of the alternatives proposed for the treatment of water with high ...