Browsing by Author "Hernández, Paola"
Now showing items 1-4 of 4
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Castro, Diego; Boiani, Lucía; Benítez, Diego; Hernández, Paola; Merlino, Alicia; Gil, Carmen; Olea Azar, Claudio; González, Mercedes; Cerecetto, Hugo; Porcal, Williams (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2009-12)Hybrid vinylthio-, vinylsulfinyl-, vinylsulfonyl- and vinylketo-benzofuroxans developed as anti-trypanosomatid agents, against Trypanosoma cruzi and Leishmania spp., have showed low micromolar IC50 values. The synthetic ...
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Toral Ponce, María; Hernández, Paola; Richter Duk, Pablo (MARCEL DEKKER INC, 1996)A continuous flow injection reaction-stopped flow detection method using derivative spectrophotometry was developed for the determination of cobalt and iron in mixtures. A conventional two-channel flow injection manifold ...
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Porcal, Williams; Hernández, Paola; González, Mercedes; Ferreira, Ana; Olea Azar, Claudio; Cerecetto, Hugo; Castro, Ana (American Chemical Society, 2008-09)New 1,2,4-thiadiazolylnitrones and furoxanylnitrones were developed and evaluated as neuroprotective agents on a human neuroblastoma (SH-SY5Y) cells model. They inhibited at low micromolar concentrations the oxidative ...
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Porcal, Williams; Hernández, Paola; Boiani, Lucía; Boiani, Mariana; Ferreira, Ana; Chidichimo, Agustina; Cazzulo, Juan J.; Olea Azar, Claudio; González, Mercedes; Cerecetto, Hugo (Elsevier Ltd, 2008-07)Hybrid compounds containing hydrazones and benzofuroxan pharmacophores were designed as potential Trypanosoma cruzi-enzyme inhibitors. The majority of the designed compounds was successfully synthesized and biologically ...