Browsing by Author "Zapata Torres, Gerald Amilcar"

Now showing items 1-7 of 7

    • Characterization, phase-solubility, and molecular modeling of inclusion complex of 5-nitroindazole derivative ... 
      Jullian Matthaei, Carolina; Morales Montecinos, Javier; Zapata Torres, Gerald Amilcar; Aguilera, Benjamín; Rodríguez Borges, Jorge; Arán, Vicente J.; Olea Azar, Claudio (PERGAMON-ELSEVIER SCIENCE LTD, 2008-05-01)
      The slightly water-soluble 5-nitroindazole derivative (5-NI) and its inclusion with either beta-cyclodextrin (beta CD) or Heptakis (2,6-di-O-methyl)-beta- cyclodextrin (DM beta CD) were investigated. The stoichiometric ...
    • Inclusion Complexes of Cyclodextrins with Galangin: a Thermodynamic and Reactivity Study 
      Jullian Matthaei, Carolina; Alfaro, Muriel; Zapata Torres, Gerald Amilcar; Olea Azar, Claudio (SPRINGER/PLENUM PUBLISHERS, 2010-10)
      The formation of the complexes of galangin (GAL) with native β-cyclodextrin (βCD), and with its substituted counterparts such as dimethyl-βCD (DMβCD) and hydroxypropyl-βCD (HPβCD), was studied by fluorescence spectra in ...
    • Quantum-chemical, NMR and X-ray diffraction studies on (±)-1-[3,4-(methylenedioxy)phenyl]-2-methylaminopropane 
      Zapata Torres, Gerald Amilcar; Cassels Niven, Bruce; Parra Mouchet, Julia; Mascarenhas, Yvonne P.; Ellena, Javier; De Araujo, A. S. (Elsevier Inc, 2008-06)
      Time-averaged conformations of ( )-1-[3,4-(methylenedioxy)phenyl]-2-methylaminopropane hydrochloride (MDMA, ‘‘ecstasy’’) in D2O, and of its free base and trifluoroacetate in CDCl3, were deduced from their 1H NMR spectra ...
    • Remote regio- and stereocontrol by the sulfinyl group: Diels–Alder reaction of sulfinyl dienols and ... 
      Almodovar, Iriux; Cardona, Wilson; Delgado Castro, Tomás; Zapata Torres, Gerald Amilcar; Caroli Rezende, Marcos; Araya Maturana, Ramiro; Maestro, M. Carmen; García Ruano, José L. (Elsevier, 2013)
      Diels–Alder cycloaddition of 8,8-dimethylnaphthalene-1,4,5(8H)-trione with diastereomeric hydroxysulfinyldienes proceeded with high yields and good p-facial and regioselectivities. The hydroxysulfoxide moiety controls ...
    • Studies of inclusion complexes of natural and modified cyclodextrin with (+)catechin by NMR and molecular modeling 
      Jullian Matthaei, Carolina; Miranda, Sebastián; Zapata Torres, Gerald Amilcar; Mendizábal Emaldía, Fernando; Olea Azar, Claudio (PERGAMON-ELSEVIER SCIENCE LTD, 2007-05)
      The aim of this paper is to describe the inclusion properties and the factors affecting the complexation selectivity and stabilization of catechin (CA) into beta-cyclodextrin (beta-CD) and two of its derivatives, namely ...
    • Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole ... 
      Pessoa Mahana, Hernán; González Lira, Christian; Fierro, Angélica; Zapata Torres, Gerald Amilcar; Pessoa Mahana, Carlos David; Ortiz Severin, Javiera; Iturriaga-Vásquez, Patricio; Reyes Parada, Miguel; Silva Matus, Paul; Saitz Barría, Claudio; Araya Maturana, Ramiro (Elsevier, 2013)
      A series of 3-(3-(4-(3-(1H-indol-3-yl)propyl)piperazin-1-yl)propyl)-1H-indole derivatives (3a–d and 5a– f) as homo- and hetero-bis-ligands, were synthesized and evaluated for in vitro affinity at the serotonin transporter ...
    • Synthesis, Docking Studies and Biological Evaluation of Benzobthiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one ... 
      Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Fiedler Temer, Jenny; Zapata Torres, Gerald Amilcar; Pessoa Mahana, Carlos David; Saitz Barría, Claudio; Araya Maturana, Ramiro (2012)
      A series of novel benzobthiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one derivatives 6a–f, 7a–f and their corresponding alcohols 8a–f were synthesized and evaluated for their affinity towards 5-HT1A receptors. The ...