Browsing by Subject "Cancer"

Now showing items 1-8 of 8

    • Associations of six adiposity-related markers with incidence and mortality from 24 cancers—findings from ... 
      Parra Soto, Solange Liliana; Cowley, Emma S.; Rezende, Leandro F. M.; Ferreccio Keadi, Catterina; Mathers, John C.; Pell, Jill P.; Ho, Frederick K.; Celis Morales, Carlos (BMC, 2021)
      Background: Adiposity is a strong risk factor for cancer incidence and mortality. However, most of the evidence available has focused on body mass index (BMI) as a marker of adiposity. There is limited evidence on ...
    • Biomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung ... 
      Díaz García, Víctor; Guerrero, Simón; Díaz Valdivia, Natalia; Lobos González, Lorena; Kogan Bocian, Marcelo; Pérez Donoso, José; Quest, Andrew F. G. (NLM (Medline), 2018)
      Background: Numerous studies have proposed the use of fluorescent semiconductor nanoparticles or quantum dots (QDs) as novel tools to label cells and tumors. However, QD applications are limited by their toxicity in ...
    • Chitosan-based nanoparticles for Intracellular delivery of ISAV fusion protein cDNA into melanoma cells: a ... 
      Robles Planells, Claudia; Sánchez-Guerrero, Giselle; Barrera Ávalos, Carlos; Matiacevich, Silvia; Rojo, Leonel E.; Pavéz, Jorge; Salas Huenuleo, Edison; Kogan, Marcelo J.; Escobar Álvarez, Alejandro; Milla, Luis A.; Fernández, Ricardo; Imarai, Mónica; Spencer, Eugenio; Huidobro Toro, Juan Pablo; Acuña Castillo, Claudio (Hindawi, 2020)
      Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation ...
    • Fatty acid conjugates of Toluidine Blue O as Amphiphilic Photosensitizers: Synthesis, solubility, photophysics ... 
      Robinson Duggon, José; Pizarro, Nancy; Gunther Sapunar, Germán; Zúñiga Núñez, Daniel; Edwards, Ana María; Greer, Alexander; Fuentealba, Denis (Wiley, 2020)
      Toluidine blue O (TBO) is a water-soluble photosensitizer that has been used in photodynamic antimicrobial and anticancer treatments, but suffers from limited solubility in hydrophobic media. In an effort to incrementally ...
    • Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci 
      Amaral, Paulo P.; Leonardi, Tommaso; Han, Namshik; Vire, Emmanuelle; Gascoigne, Dennis K.; Arias Carrasco, Raúl; Buscher, Magdalena; Pandolfini, Luca; Zhang, Anda; Pluchino, Stefano; Maracaja Coutinho, Vinicius; Nakaya, Helder I.; Hemberg, Martin; Shiekhattar, Ramin; Enright, Anton J.; Kouzarides, Tony (BIOMED Central Ltd., 2018)
      Background: The mammalian genome is transcribed into large numbers of long noncoding RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly due to their low sequence conservation and ...
    • Heterocyclic curcumin derivatives of pharmacological interest: Recent progress 
      Martínez Cifuentes, Maximiliano; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (Bentham Science Publishers B.V., 2015)
      © 2015, Bentham Science Publishers. Curcumin, a natural yellow polyphenol, is isolated from the herb Curcuma longa L. (turmeric), a member of the ginger family. It has been extensively studied due to their multiple ...
    • Is mitochondrial dysfunction a common root of noncommunicable chronic diseases? 
      Díaz Vegas, Alexis; Sánchez Aguilera, Pablo; Krycer, James R; Morales, Pablo E.; Monsalves Álvarez, Matías; Cifuentes Koster, Mariana; Rothermel, Beverly A.; Lavandero González, Sergio (Endocrine Society, 2020)
      Mitochondrial damage is implicated as a major contributing factor for a number of noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and insulin resistance/type 2 diabetes. Here, we discuss ...
    • Nanomedicine and nanotoxicology: the pros and cons for neurodegeneration and brain cancer 
      Catalán Figueroa, Johanna; Palma Florez, Sujey; Alvarez, Gonzalo; Fritz, Hans F.; ara, Miguel O.; Morales, Javier O. (Future Medicine Ltd., 2016)
      Current strategies for brain diseases are mostly symptomatic and noncurative. Nanotechnology has the potential to facilitate the transport of drugs across the blood-brain barrier and to enhance their pharmacokinetic ...