Browsing by Subject "Cardioprotection"

Now showing items 1-4 of 4

    • Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated ... 
      Kalkhoran, Siavash Beikoghli; Kriston-Vizi, Janos; Hernández Resendiz, Sauri; Crespo Avilan, Gustavo E.; Rosdah, Ayeshah A.; Lees, Jarmon G.; Simoes Da Costa, Joanna Rodrigues; Ling, Naomi X. Y.; Holien, Jessica K.; Samangouei, Parisa; Chinda, Kroekkiat; Yap, En Ping; Riquelme Meléndez, Jaime Andrés; Ketteler, Robin; Yellon, Derek M.; Lim, Shiang Y.; Hausenloy, Dereck J. (Oxford University Press, 2022)
      Aims Genetic and pharmacological inhibition of mitochondrial fission induced by acute myocardial ischaemia/reperfusion injury (IRI) has been shown to reduce myocardial infarct size. The clinically used anti-hypertensive ...
    • Light-induced release of the cardioprotective peptide angiotensin-(1-9) from thermosensitive liposomes with ... 
      Bejarano, Julián; Rojas, Aldo; Ramírez Sagredo, Andrea; Riveros Salvatierra, Ana; Morales Zavala, Francisco; Flores, Yvo; Riquelme Meléndez, Jaime; Guzmán, Fanny; Araya, Eyleen; Chiong Lay, Mario; Ocaranza, María Paz; Morales Montecinos, Javier; Villamizar Sarmiento, María Gabriela; Sánchez Vergara, Gina; Lavandero González, Sergio; Kogan, Marcelo J. (Elsevier, 2020)
      Angiotensin-(1-9), a component of the non-canonical renin-angiotensin system, has a short half-life in blood. This peptide has shown to prevent and/or attenuate hypertension and cardiovascular remodeling. A controlled ...
    • Targeting the Endothelium to Achieve Cardioprotection 
      Herrera Zelada, Nicolás Gabriel; Zúñiga Cuevas, Úrsula Almendra; Ramírez Reyes, Andrés Ignacio; Lavandero González, Sergio; Riquelme Meléndez, Jaime (Frontiers Media, 2021)
      Despite considerable improvements in the treatment of myocardial infarction, it is still a highly prevalent disease worldwide. Novel therapeutic strategies to limit infarct size are required to protect myocardial function ...
    • The role of PI3K alpha isoform in cardioprotection 
      Rossello, Xavier; Riquelme, Jaime A.; He, Zhenhe; Taferner, Stasa; Vanhaesebroeck, Bart; Davidson, Sean M.; Yellon, Derek M. (Springer, 2017)
      Ischemic preconditioning (IPC) limits myocardial infarct size through the activation of the PI3K-Akt signal cascade; however, little is known about the roles of individual PI3K isoforms in cardioprotection. We aimed, ...