Browsing by Subject "JAK"

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    • Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2 
      Ocaranza, María Paz; Valderas, Patricio; Moya, Jackeline; Gabrielli, Luigi; Godoy, Iván; Córdava, Samuel; Mac Nab, Paul; García Nannig, Lorena; Farías, Luis; Jalil, Jorge E. (BMC, 2020)
      BackgroundThe intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ...