Browsing by Subject "Leishmaniasis"

Now showing items 1-3 of 3

    • CEMiTool: a Bioconductor package for performing comprehensive modular co expression analyses 
      Russo, Pedro S. T.; Ferreira, Gustavo R.; Cardozo, Lucas E.; Buerger, Matheus C.; Arias Carrasco, Raúl; Maruyama, Sandra R.; Hirata, Thiago D. C.; Lima, Diogenes S.; Passos, Fernando M.; Fukutani, Kiyoshi F.; Lever, Melissa; Silva, Joao S.; Maracaja Coutinho, Vinicius; Nakaya, Helder I. (BIOMED Central, 2018)
      Background: The analysis of modular gene co-expression networks is a well-established method commonly used for discovering the systems-level functionality of genes. In addition, these studies provide a basis for the discovery ...
    • In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles 
      Boiani, Lucia; Gerpe, Alejandra; Arán, Vicente; Torres de Ortiz, Susana; Serna, Elva; Vera de Bilbao, Ninfa; Sanabria, Luis; Yaluff, Gloria; Nakayama, Héctor; Rojas de Arias, Antonieta; Maya Arango, Juan; Morello, J.; Cerecetto, Hugo; González, Mercedes (2009)
      Previously, we have identified a series of 5-nitroindazoles with good antiprotozoal activities, against Trypanosoma cruzi epimastigotes and Trichomonas vaginalis. Most of them have shown very low unspecific toxicity on ...
    • Network-based approaches reveal potential therapeutic targets for host-directed antileishmanial therapy ... 
      Martínez Hernández, Eduardo; Hammoud, Zaynab; De Sousa, Alessandra Mara; Kramer, Frank; Do Monte-Neto, Rubens L.; Maracajá Coutinho, Vinicius; Martin, Alberto J. M. (Amer Soc Microbiology, 2021)
      Leishmania parasites are the causal agent of leishmaniasis, an endemic disease in more than 90 countries worldwide. Over the years, traditional approaches focused on the parasite when developing treatments against ...