Browsing by Subject "Senescence"

Now showing items 1-2 of 2

    • A phenolic-rich extract from ugni molinae berries reduces abnormal protein aggregation in a cellular model ... 
      Pérez Arancibia, Rodrigo Nicolás; Ordóñez, José Luis; Rivas, Alexis; Pihán, Philippe; Sagredo, Alfredo; Ahumada, Ulises; Barriga, Andrés; Seguel, Ivette; Cárdenas, César; Vidal, René L.; Hetz Flores, Claudio Andres; Delporte Vergara, Carla Luz (Public Library Science, 2021)
      Accumulation of misfolded proteins in the brain is a common hallmark of most age-related neurodegenerative diseases. Previous studies from our group identified the presence of anti-inflammatory and antioxidant compounds ...
    • Pharmacological blockade of NLRP3 inflammasome/IL1β-positive loop mitigates endothelial cell senescence and ... 
      Romero, Alejandra; Dongil, Pilar; Valencia, Inés; Vallejo, Susana; San Hipólito Luengo, Álvaro; Díaz Araya, Guillermo; Bartha, José L.; González Arlanzón, María M.; Rivilla, Fernando; Cuesta, Fernando de la; Sánchez Ferrer, Carlos; Peiró, Concepción (International Society on Aging and Disease, 2022)
      The clinical relevance of IL-1 beta in chronic inflammation underlying atherosclerosis has been reinforced by recent evidence associating pharmacological inhibition of the cytokine with lower cardiovascular risk. Previously, ...