Now showing items 10237-10256 of 11553

    • Sánchez, Gina; Pedrozo Cibils, Zully; Domenech Lira, Raúl; Hidalgo Tapia, María Cecilia; Donoso Laurent, Paulina (ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2005-12)
      We have shown previously that electrically induced tachycardia effectively produces myocardial preconditioning. Among other effects, tachycardia increases calcium release rates in microsomal fractions enriched in sarcoplasmic ...
    • Domenech Lira, Raúl; Macho Fisher, Pilar; Vélez, Diego; Sánchez, Gina; Liu, Xueliang; Dhalla, Naranjan (Lippincott Williams and Wilkins, 1998)
      Background - Myocardial ischemic preconditioning is a well-known phenomenon, however there is scant information in regard to nonischemic preconditioning. Methods and Results - We studied in anesthetized dogs the preconditioning ...
    • Meyer, Lital; Concepción, Roberto; Zamorano, Nibaldo; Armstrong, Macarena; Castro, Leonardo; Mujica, Maximiliano; Asenjo, Rene (2012)
      Tachycardiomyopathy is a potentially reversible cause of heart failure. It can be induced by supraventricular or ventricular arrhythmias. When these are treated, systolic function improves or normalizes. We report a 20 ...
    • Zamorano, Mauricio; Castillo Peñaloza, Rodrigo Luis; Beltran, Jorge F.; Herrera, Lisandra; Farías, Joaquín A.; Antileo, Christian; Aguilar Gallardo, Cristóbal; Pessoa, Adalberto; Calle, Yolanda; Farías, Jorge G. (Frontiers Media, 2021)
      Ischemia is a severe condition in which blood supply, including oxygen (O), to organs and tissues is interrupted and reduced. This is usually due to a clog or blockage in the arteries that feed the affected organ. ...
    • Pridmore, Pat; Carr-Hill, Roy; Amuyunzu-Nyamongo, Mary; Lang’o, Daniel; McCowan, Tristan; Charnes Cars, Gabriela (Springer, 2015)
      As momentum grows for a sustainable urbanisation goal in the post-2015 development agenda, this paper reports on an action research study that sought to tackle the urban health divide by enabling intersectoral action on ...
    • Sedeno, Lucas; Piguet, Olivier; Abrevaya, Sofia; Desmaras, Horacio; García Cordero, Indira; Baez, Sandra; Alethia de la Fuente, Laura; Reyes, Pablo; Tu, Sicong; Moguilner, Sebastián; Lori, Nicolás; Landin Romero, Ramon; Matallana, Diana; Slachevsky Chonchol, Andrea; Torralva, Teresa; Chialvo, Dante; Kumfor, Fiona; García, Adolfo M.; Manes, Facundo; Hodges, John R.; Ibánez, Agustín (Wiley, 2017)
      Biomarkers represent a critical research area in neurodegeneration disease as they can contribute to studying potential disease-modifying agents, fostering timely therapeutic interventions, and alleviating associated ...
    • Ugalde Prieto, Héctor; Yubini, María Cecilia; Sanhueza, María Ignacia; Ayala, Francisco; Chaigneau, Ernesto; Dussaillant, Gastón; García, Sebastián; Farías, Eric; Villagra, Katia; Inostroza, Paula (Sociedad Medica de Santiago, 2017)
      © 2017, Sociedad Medica de Santiago. All rights reserved. Background: Tako-tsubo Syndrome (TTS) is characterized by transient regional systolic dysfunction of the left ventricle (LV), mimicking myocardial infarction. It ...
    • Rau, Carlos M.; Kauffmann, Max; Rau, Carlos L.; Cereceda, Mauricio; Neira Castro, Gabriel; Massardo, Teresa (2011)
      Tako-Tsubo syndrome resembles an acute myocardial infarction in symptoms, laboratory parameters and electrocardiographic changes. However, angiography does not show evidence of coronary occlusion, and typically an apical ...
    • Varela Moraga, Virginia Miriam; Arce Montero, Constanza Belén; Osorio Saldaña, Camila Paz; Ramírez Carreño, Fernanda; Quezada Gaponov, Camilo (Universidad de Chile. Facultad de Medicina. Departamento de Fonoaudiología, 2023)
      Las investigaciones muestran que un número importante de niños nacidos prematuros (antes de las 37 semanas de gestación) presentan dificultades en su desarrollo, entre ellas el desarrollo lingüístico. Las investigaciones ...
    • Borghero, Francesca; Martínez, Vania; Zitko, Pedro; Vohringer, Paul; Cavada Chacón, Gabriel; Rojas Castillo, María Graciela (Sociedad Médica de Santiago, 2018-04)
      Background: There is a paucity of validated instruments for screening depression in adolescent populations in Chile. Aim: To determine the diagnostic accuracy of the adolescent version of Patient Health Questionnaire-9 ...
    • Salazar Onfray, Flavio; Pereda, Cristián; Reyes, Diego; López, Mercedes N. (2013)
      Here we summarize 10 years of effort in the development of a biomedical innovation with global projections. This innovation consists of a novel method for the production of therapeutic dendritic-like cells called Tumor ...
    • Prado, Arturo C.; Castillo, Paulo F. (2003)
    • Meyer, Lital; Concepción, Roberto; Zamorano, Nibaldo; Armstrong, Macarena; Castro, Leonardo; Mujica, Maximiliano; Asenjo, René (SOC MEDICA SANTIAGO, 2012-02)
      Tachycardiomyopathy is a potentially reversible cause of heart failure. It can be induced by supraventricular or ventricular arrhythmias. When these are treated, systolic function improves or normalizes. We report a 20 ...
    • Lobos González, Lorena; Silva, Verónica; Araya, Mariela; Restovic, Franko; Echeñique, Javiera; Oliveira Cruz, Luciana; Fitzpatrick, Christopher; Briones, Macarena; Villegas, Jaime; Villota, Claudio; Vidaurre, Soledad; Borgna, Vincenzo; Socias, Miguel; Valenzuela, Sebastián; López, Constanza; Socias, Teresa; Varas, Manuel; Díaz, Jorge; Burzio, Luis O.; Burzio, Verónica A. (Impact Journals, 2016)
      We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy against ...
    • Borgna Christie, Vincenzo; Lobos González, Lorena; Guevara, Francisca; Landerer, Eduardo; Bendek, Maximiliano; Ávila, Rodolfo; Silva, Verónica; Villota, Claudio; Araya, Mariela; Rivas, Alexis; López, Constanza; Socias, Teresa; Castillo, Jorge; Alarcón Navarrete, Luis; Burzio, Luis O.; Burzio, Verónica A.; Villegas, Jaime (Ivyspring International Publisher, 2020)
      Knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, supporting a selective therapy against different types of cancer. In ...
    • Nassif, Melissa; Hetz Flores, Claudio (LANDES BIOSCIENCE, 2011-04)
    • Nassif, Melissa; Hetz Flores, Claudio (Taylor and Francis Inc., 2011)
      Several neurodegenerative diseases share a common neuropathology, primarily featuring the presence of abnormal protein inclusions in the brain containing specific misfolded proteins. Strategies to decrease the load of ...
    • Durán Aniotz, Claudia; Cornejo, Víctor Hugo; Hetz Flores, Claudio (Oxford University Press, 2016)
      This scientific commentary refers to 'Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse', by Peng et al. (doi:10.1093/brain/awv385).
    • Durán Aniotz, Claudia; Cornejo, Victor Hugo; Hetz Flores, Claudio (Oxford University Press, 2016)
    • Lillo Moya, José Ignacio; Rojas Solé, Catalina Andrea; Muñoz Salamanca, Diego Ignacio; Panieri, Emiliano; Saso, Luciano; Rodrigo Salinas, Ramón (MDPI, 2021)
      Ischemic heart disease is a leading cause of death worldwide. Primarily, ischemia causes decreased oxygen supply, resulting in damage of the cardiac tissue. Naturally, reoxygenation has been recognized as the treatment of ...