Now showing items 4330-4349 of 11553

    • Araya López, Héctor; Sepulveda, Hugo; Lizama, Carlos O.; Vega Villa, Oscar; Jerez, Sofia; Briceño, Pedro F.; Thaler, Roman; Riester, Scott M.; Antonelli Anativia, Marcelo; Salazar Onfray, Flavio; Rodríguez Vives, Juan Pablo; Moreno, Ricardo D.; Montecino, Martín; Charbonneau, Martine; Dubois, Claire; Galindo Díaz, Mario; Stein, Gary; van Wijnen, Andre (Wiley-Liss Inc., 2018)
      Osteoblast differentiation is controlled by transcription factor RUNX2 which temporally activates or represses several bone-related genes, including those encoding extracellular matrix proteins or factors that control ...
    • Dissen, Gregory A.; Garcia-Rudaz, Cecilia; Tapia, Veronica; Parada, Luis F.; Hsu, Sheau Yu Teddy; Ojeda, Sergio R. (2006)
      The insulin receptor-related receptor (IRR) is a member of the insulin receptor family that, on its own, recognizes neither insulin nor any of the identified insulin-related peptides. In both the nervous system and peripheral ...
    • Moreno Moreno, Claudia; Epunan,; Minguell, José J. (2000)
      Using myeloid cell lines, it has been demonstrated that hyaluronan modulates transmembrane and soluble CD44H expression in immature (KG1a) but not mature (KG1) progenitors. Concomitantly, cell proliferation is decreased. ...
    • Faunes, Fernando; Sanchez, Natalia; Moreno, Mauricio; Olivares, Gonzalo H.; Lee-Liu, Dasfne; Almonacid, Leonardo; Slater, Alex W.; Norambuena, Tomas; Taft, Ryan J.; Mattick, John S.; Melo, Francisco; Larrain, Juan (2011)
      Transposable elements comprise a large proportion of animal genomes. Transposons can have detrimental effects on genome stability but also offer positive roles for genome evolution and gene expression regulation. Proper ...
    • Bergeron, Sadie A.; Milla, Luis A.; Villegas, Rosario; Shen, Meng Chieh; Burgess, Shawn M.; Allende Connelly, Miguel; Karlstrom, Rolf O.; Palma, Verónica (2008)
      The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. ...
    • Gatica, Sebastian; Eltit, Felipe; Santibanez, Juan F.; Varela, Diego; Cabello-Verrugio, Claudio; Simon, Felipe (NLM (Medline), 2019)
      Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.BACKGROUND: Main pathological features detected during sepsis and endotoxemia include over-secretion of pro-inflammatory ...
    • Sepúlveda, S.; Valenzuela, L.; Ponce, I.; Sierra, S.; Bahamondes, P.; Ramirez, S.; Rojas, V.; Kemmerling Weis, Ulrike; Galanti Garrone, Norbel; Cabrera, G. (2014)
      Trypanosoma cruzi is the etiological agent of Chagas disease. The parasite has to overcome oxidative damage by ROS/RNS all along its life cycle to survive and to establish a chronic infection. We propose that T. cruzi is ...
    • Sepúlveda, S.; Valenzuela, L.; Ponce, I.; Sierra, S.; Bahamondes, P.; Ramírez, S.; Rojas, V.; Kemmerling Weis, Ulrike; Galanti Garrone, Norbel; Cabrera Vallejos, Gonzalo (John Wiley & Sons, 2014)
      Trypanosoma cruzi is the etiological agent of Chagas disease. The parasite has to overcome oxidative damage by ROS/RNS all along its life cycle to survive and to establish a chronic infection. We propose that T. cruzi is ...
    • Maldonado Maldonado, Edio; Rojas, Diego A.; Moreira Ramos, Sandra; Urbina, Fabiola; Miralles, Vicente J.; Solari Illescas, Aldo; Venegas Hermosilla, Juan Antonio (Springer, 2015)
      Chagas disease, caused by the protozoan Trypanosoma cruzi, is a major parasitic disease that affects millions of people in America. However, despite the high impact of this disease on human health, no effective and ...
    • Muñoz, Matías I.; Penna Varela, Mario (Springer Verlag, 2016)
      © 2016, Springer-Verlag Berlin Heidelberg.Animals relying on acoustic signals for communication must cope with the constraints imposed by the environment for sound propagation. A resource to improve signal broadcast is the ...
    • Romero, Carlos M.; Cornejo, Rodrigo A.; Gálvez, L. Ricardo; Llanos, Osvaldo P.; Tobar, Eduardo A.; Berasaín, M. Angélika; Arellano, Daniel H.; Larrondo, Jorge F.; Castro, José S. (2009)
      Objectives: The aim of the study was to evaluate the safety of extended prone position ventilation (PPV) and its impact on respiratory function in patients with severe acute respiratory distress syndrome (ARDS). Design: ...
    • Quatrini, Raquel; Appia-Ayme, Corinne; Denis, Yann; Jedlicki,; Holmes, David S.; Bonnefoy, Violaine (BioMed Central Ltd., 2009)
      Background: Acidithiobacillus ferrooxidans gains energy from the oxidation of ferrous iron and various reduced inorganic sulfur compounds at very acidic pH. Although an initial model for the electron pathways involved in ...
    • Talhouk Pugliese, Omar; Lombardi Solari, Juan; Ferreres, Alberto R. (Springer, 2014)
      The notion that consent to surgery must be informed implies not only that information should be provided by the surgeon but also that the information should be understood by the patient in order to give a foundation to ...
    • Hurst, R. S.; Latorre, R.; Toro, L.; Stefani, E. (1995)
      External barium ions inhibit K+ currents of Xenopus oocytes expressing ShH4 Δ646, the non-inactivating deletion of the Shaker K+ channel. At the macroscopic level, Ba2+ block comprises both a fast and a slow component. The ...
    • Morera, F. J.; Wolff, D.; Vergara, C. (2003)
      We have characterized the effect of external copper on the gating properties of the large-conductance calcium- and voltage-sensitive potassium channel from skeletal muscle, incorporated into artificial bilayers. The ...
    • Valenzuela-Moguillansky, Camila; Reyes-Reyes, Alejandro; Gaete, María I. (Frontiers Media S. A, 2017)
      © 2017 Valenzuela-Moguillansky, Reyes-Reyes and Gaete.Fibromyalgia is a widespread chronic pain disease characterized by generalized musculoskeletal pain and fatigue. It substantially affects patients’ relationship with ...
    • Valenzuela, R.; Hernández Rodas, M. C.; Espinosa, A.; Rincón Cervera, Miguel Ángel; Romero, N.; Barrera Ramírez, Cynthia Andrea; Marambio, M.; Vivero, J.; Valenzuela, A. (2016)
      Long-chain polyunsaturated fatty acids (LCPUFA) which are synthesized mainly in the liver have relevant functions in the organism. A diet high in fat (HFD) generates an increase in the levels of fat and induces oxidative ...
    • Reig Cardarella, Germán; Cerda Villablanca, Mauricio; Sepúlveda Salazar, Néstor; Flores Campo, Daniela; Castañeda, Víctor; Masazumi, Tada; Härtel, Steffen; Concha Nordemann, Miguel (Nature Publishing Group, 2017-06-05)
      The spreading of mesenchymal-like cell layers is critical for embryo morphogenesis and tissue repair, yet we know little of this process in vivo. Here we take advantage of unique developmental features of the non-conventional ...
    • Vamre, Tone B.Aaman; Stalsberg, Helge; Thomas, David B.; Berry, G.; Maclennan, R.; Shearman, R.; Jelihovsky, T.; Booth, J. Cooper; Molina, R.; Martinez, L.; Salas O., Marcela; Dabacens, A.; Zhiheng, Cheng; Yun, Tao; Wei, Hu Yong; Cuadros, A.; Aristizabal, N.; Ebeling, K.; Nishan, (2006)
      The association between oral contraceptive (OC) use and benign breast changes in extra-tumoral breast tissue was studied histologically in 1,503 breast cancer patients from The WHO Collaborative Study of Neoplasia and ...
    • Pacheco, Carla R.; Morales, Camila N.; Ramírez, Alejandra E.; Muñoz, Francisco J.; Gallegos, Scarlet S.; Caviedes, Pablo A.; Aguayo, Luis G.; Opazo, Carlos M. (Blackwell, 2015)
      It has been postulated that the accumulation of extracellular asynuclein (a-syn) might alter the neuronal membrane by formation of ‘pore-like structures’ that will lead to alterations in ionic homeostasis. However, this ...