Now showing items 5915-5934 of 11561

    • Diamanti-Kandarakis, Evanthia; Spritzer, Poli Mara; Sir Petermann, Teresa; Motta, Alicia Beatriz (2012)
      The heterogeneity of Polycystic Ovary Syndrome (PCOS) emphasizes the need for a consensual review of the data concerning its diagnosis and treatment and for determination of the relationship between the development of PCOS ...
    • Celis Morales, Carlos; Pérez Bravo, Francisco; Ibañes, Luis; Sanzana, Ruth; Hormazabal, Edison; Ulloa, Natalia; Calvo, Carlos; Bailey, Mark E.S.; Gill, Jason M.R. (2011)
      Background: Effects of urbanisation on diabetes risk appear to be greater in indigenous populations worldwide than in populations of European origin, but the reasons are unclear. This cross-sectional study aimed to determine ...
    • Eyzaguirre, Francisca; Mericq, Verónica (2009)
      The prevalence of obesity among children and adolescents is progressively increasing around the world. One of the important consequences of obesity is the development of insulin resistance (IR). This condition has a ...
    • López López, J. A.; Calvillán,; Durruty, P.; Rocha, (1992)
      Secretion and peripheral sensitivity to insulin was investigated in diabetic patients with secondary failure to oral hypoglycemic drugs. 8 patients with secondary failure (non responders), 7 non insulin dependent diabetic ...
    • Burrows, Raquel; Leiva Balich, Laura; Burgueño, Medardo; Maggi M., Aida; Giadrosic R, Vinka; Díaz Bustos, Erik; Lera Marques, Lydia; Albala Brevis, Cecilia (2006)
      Backgrounds: There is a high prevalence of obesity and hyperinsulinism among Chilean prepuberal children. Aim: To evaluate insulin sensitivity (IS) using fasting insulin, the Homeostasis Model Assessment (HOMA) and ...
    • Contreras Contreras, Marlene Daniella; Villanuev,; Calvillán,; Morales Morales, Eduardo; Mella Mella, Mitzy; Pérez,; Rios, Marco; Zura,; Maiz,; Arteaga, (1991)
      The hyperinsulinemic, euglycemic clamp technique was used to test the hypothesis that--when expressed per kilogram of lean body mass--there is a sex-difference in peripheral insulin-mediated glucose disposal (M), as proposed ...
    • Parra, Valentina; Verdejo, Hugo E.; Iglewski, Myriam; Del Campo, Andrea; Troncoso, Rodrigo; Jones, Deborah; Zhu, Yi; Kuzmicic Previtali, Jovan Paolo; Pennanen, Christian; López Crisosto, Camila; Jaña, Fabián; Ferreira, Jorge; Noguera, Eduard; Chiong Lay, Mario; Bernlohr, David A.; Klip, Amira (2014)
      Insulin regulates heart metabolism through the regulation of insulin-stimulated glucose uptake. Studies have indicated that insulin can also regulate mitochondrial function. Relevant to this idea, mitochondrial function ...
    • Espinosa, Alejandra; Campos, Cristian; Díaz Vegas, Alexis; Galgani Fuentes, José; Juretic Díaz, Nevenka Militza; Osorio Fuentealba, César; Bucarey, José L.; Tapia, Gladys; Valenzuela, Rodrigo; Contreras Ferrat, Ariel Eduardo; Llanos Vidal, Paola; Jaimovich Pérez, Enrique (2013)
      Insulin resistance is defined as a reduced ability of insulin to stimulate glucose utilization. C57BL/6 mice fed with a high-fat diet (HFD) are a model of insulin resistance. In skeletal muscle, hydrogen peroxide (H2O2) ...
    • García Huerta, Paula; Troncoso Escudero, Paulina; Wu, Di; Thiruvalluvan, Arun; Cisternas, Marisol; Henríquez, Daniel R.; Plate, Lars; Chana-Cuevas, Pedro; Saquel, Cristian; Thielen, Peter; Longo, Kenneth A.; Geddes, Brad J.; Lederkremer, Gerardo Z.; Sharma, Neeraj; Shenkman, Marina; Naphade, Swati; Sardi, S. Pablo; Spichiger, Carlos; Richter, Hans G.; Court, Felipe A.; Tshilenge, Kizito Tshitoko; Ellerby, Lisa M.; Wiseman, R. Luke; Gonzalez Billault, Christian; Bergink, Steven; Vidal, René L.; Hetz Flores, Claudio (Springer, 2020)
      Impaired neuronal proteostasis is a salient feature of many neurodegenerative diseases, highlighting alterations in the function of the endoplasmic reticulum (ER). We previously reported that targeting the transcription ...
    • Ibarra, Cristián; Estrada Hormazábal, Manuel; Carrasco Mujica, Loreto; Chiong Lay, Mario; Liberona Leppe, José; Cárdenas, César; Díaz Araya, Guillermo; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Amer Biochemistry Molecular Biology, 2004-02-27)
      In the heart, insulin-like growth factor-1 (IGF-1) is a pro-hypertrophic and anti-apoptotic peptide. In cultured rat cardiomyocytes, IGF-1 induced a fast and transient increase in Ca-i(2+) levels apparent both in the nucleus ...
    • Foncea, Rocío; Andersson, Monica; Ketterman, Albert; Blakesley, Vicky; Sapag Hagar, Mario; Sugden, Peter H.; LeRoith, Derek; Lavandero González, Sergio (1997)
      In response to insulin-like growth factor-I (IGF-I), neonatal rat cardiac myocytes exhibit a hypertrophic response. The elucidation of the IGF- I signal transduction system in these cells remains unknown. We show here that ...
    • Osorio, Marcial; Torres, Jorge; Moya, Fernando; Pezzullo, John; Salafia, Carolyn; Baxter, Robert; Schwander, Jurg; Fant, Michael (Elsevier Ireland Ltd, 1996)
      Cord sera were obtained from term, Chilean newborns exhibiting various patterns of intrauterine growth and assayed for IGF-1, IGF-2, IGFBP-1, IGFBP-2, and IGFBP-3 by specific radioimmunoassays (RIA). Serum levels of each ...
    • Contreras, P.; Araya, V. (1992)
    • Liberman, Paulina; Valenzuela,; Hernández,; Miranda, Daniela; Salazar, G.; Castillo, Andrea (1991)
      A 25 year old woman developed severe episodes of hypoglycemia during the first weeks of pregnancy. Insulin blood levels of 53 uU/ml and Peptide C levels of 6.5 ng/dl were shown associated to a blood glucose level of 34 ...
    • Lammoglia H., Juan Javier; Hernández C., María Isabel; Unanue Morales, Nancy; Román R., Rossana; Villanueva B., Jorge; Avila A., Alejandra; Mericq, Verónica; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando (2008)
      Insulinoma is a very uncommon tumor in children, with an incidence in adults of 2 per million inhabitants.Clinical manifestations include neuroglycopenic or autonomic manifestations due to hypoglycemia. Wedescribe 2 pediatric ...
    • Reyes Jedlicki, Marcela; Díaz, Erick; Lera Marques, Lydia; Burrows, Raquel (2011)
      Background: In the last decades, a seven to nine fold increase in the prevalence of teenage obesity and overweight has occurred. Aim: To assess energy intake and metabolism in a sample of overweight and obese adolescents. ...
    • Vergara, Daniela; Ávila, Daniela; Escobar, Elizabeth; Carrasco Pozo, Catalina; Sánchez Córdova, Andrés; Gotteland Russell, Martín (BioMed Central, 2015)
      Background: Respiratory diseases are associated with pulmonary oxidative stress and inflammatory processes. Though studies in animal models suggest that dietary polyphenols improve lung injury, no intervention studies were ...
    • Araneda, Jacqueline; Bustos, Patricia; Cerecera, Francisco; Amigo, Hugo (Instituto Nacional de Salud Publica, 2015)
      Objective. To estimate the association between the intake of sugar-sweetened non-alcoholic beverages and body mass index (BMI) in Chilean school children. Materials and methods. Food consumption frequency data were analyzed ...
    • Benleulmi, Salah S.; Matysiak, Julien; Henríquez, Rodrigo R.; Vaillant, Cédric; Lesbats, Paul; Calmels, Christina; Naughtin, Monica; León, Oscar; Skalka, Anna Marie; Ruff, Marc; Lavigne, Marc; Andreola, Marie Line; Parissi, Vincent (BioMed Central, 2015)
      Background: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by ...
    • Burgos, Soledad; Madrid, Miguel A.; Maldonado, Ana; Medina, Felipe; Iglesias, Verónica (Taylor and Francis Ltd., 2018)
      © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Vulnerability assessments are commonly based on complex indices that may be inappropriate for characterizing risks in small groups of people exposed to ...