Browsing by Title Artículos de revistas

Now showing items 9349-9368 of 11553

    • Role of cytochrome P450 enzymes in the metabolism of antineoplastic drugs Papel de las enzimas citocromo ... 
      Quiñones, Luis S.; Rosero, Mario P.; Roco, Ángela A.; Moreno, Iván T.; Sasso, Jaime A.; Varela, Nelson F.; Cáceres, Dante L.; Saavedra, Iván S. (2008)
      Cytochrome P450 enzymes are very important to metabolize anti-carcinogenic agents. Therefore, understanding the role of these enzymes and their allele variants in the bioactivation or detoxification of drugs could greatiy ...
    • Role of cytokine gene polymorphisms in gastric cancer risk in Chile 
      González Hormazábal, Patricio; Musleh, Maher; Bustamante, Marco; Stambuk, Juan; Escandar, Susana; Valladares, Hector; Lanzarini, Enrique; Chiong, Hector; Rojas, Jorge; Castro, V. Gonzalo; Rubio-Reyes, Cristian; Jara, Lilian; Berger, Zoltan (International Institute of Anticancer Research, 2014)
      Aim: To assess the role of pro- and anti-inflammatory polymorphisms in gastric cancer susceptibility. Patients and Methods: We genotyped 12 polymorphisms in eight cytokine genes (Interleukin-1β-IL1B-, IL8, IL17A, IL17F, ...
    • Role of dendritic cells in the induction of lymphocyte tolerance 
      Osorio, Fabiola; Fuentes, Camila; López, Mercedes N.; Salazar Onfray, Flavio; González, Fermín E. (Frontiers Media, 2015)
      The ability of dendritic cells (DCs) to trigger tolerance or immunity is dictated by the context in which an antigen is encountered. A large body of evidence indicates that antigen presentation by steady-state DCs induces ...
    • Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases 
      Mackern-Oberti, Juan Pablo; Llanos, Carolina; Vega, Fabián; Salazar Onfray, Flavio; Riedel, Claudia A.; Bueno, Susan M.; Kalergis, Alexis M. (Elsevier, 2015)
      Dendritic cells (DCs) play a key role in the activation of the immune response against pathogens, as well as in the modulation of peripheral tolerance to self-antigens (Ags). Furthermore, an imbalance in the activating/inhibitory ...
    • Role of dietary alpha- and gamma-tocopherol from Rosa mosqueta oil in the prevention of alterations induced ... 
      Tapia Opazo, Gladys; Silva, David; Romero Palacios, Nalda; Pettinelli, Paulina; Dossi, Camila G.; Miguel, Manuel de; González Mañán, Daniel Alonso (Elsevier, 2018)
      Objective: The aim of this study was to evaluate the contribution of tocopherols present in Rosa mosqueta oil (RM) in the prevention of high-fat diet (HFD)-induced alterations. Methods: Male C57 BL/6 J mice (n = 9/group) ...
    • Role of dihydrotestosterone (DHT) on TGF-β1 signaling pathway in epithelial ovarian cancer cells 
      Kohan Ivani, Karla; Gabler Neale, Fernando; Selman,; Vega Blanco, María Margarita; Romero Osses, Carmen (Springer Verlag, 2016)
      © 2015, The Author(s).Purpose: One of the hypotheses regarding the genesis of epithelial ovarian cancer involves the action of androgens on the proliferation of epithelial ovarian cells, as well as inclusion cysts. The ...
    • Role of endogenous opioids in the cardiovascular responses to asphyxia in fetal sheep 
      Espinoza,; Riquelme,; Germain,; Tevah,; Parer,; Llanos, (1989)
      Intravenous administration of the opioid receptor antagonist naloxone to asphyxiated fetal sheep increases the arterial blood pressure. We examined the hypothesis that endogenous opioids modify the cardiac output distribution ...
    • Role of epitranscriptomic and epigenetic modifications during the lytic and latent phases of herpesvirus infections 
      Soto, Abel A.; Ortiz, Gerardo; Contreras, Sofía; Soto Rifo, Ricardo Andrés; González, Pablo A. (MDPI, 2022)
      Herpesviruses are double-stranded DNA viruses occurring at a high prevalence in the human population and are responsible for a wide array of clinical manifestations and diseases, from mild to severe. These viruses are ...
    • Role of epstein-barr virus and human papillomavirus coinfection in cervical cancer: Epidemiology, Mechanisms ... 
      Blanco, Rances; Carrillo Beltrán, Diego; Osorio, Julio C.; Calaf, Gloria M.; Aguayo González, Francisco (MDPI, 2020)
      High-risk human papillomavirus (HR-HPV) is etiologically associated with the development and progression of cervical cancer, although other factors are involved. Epstein-Barr virus (EBV) detection in premalignant and ...
    • Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1 
      Vivar Sánchez, Raúl; Humeres, Claudio; Anfossi, Renatto; Bolívar, Samir; Catalán Díaz, Mabel; Hill, Joseph; Lavandero González, Sergio; Díaz Araya, Guillermo (Elsevier, 2020)
      Cardiac fibroblasts (CFs) are necessary to maintain extracellular matrix (ECM) homeostasis in the heart. Normally, CFs are quiescent and secrete small amounts of ECM components, whereas, in pathological conditions, they ...
    • Role of heterotrimeric G protein and calcium in cardiomyocyte hypertrophy induced by IGF-1 
      Carrasco Mujica, Loreto; Cea, Paola; Rocco, Paola; Peña Oyarzún, Daniel; Rivera Mejías, Pablo; Sotomayor Flores, Cristian Alejandro; Quiroga, Clara; Criollo Céspedes, Alfredo; Ibarra, Cristián; Chiong Lay, Mario; Lavandero González, Sergio (Wiley-Liss, 2014)
      In the heart, insulin‐like growth factor‐1 (IGF‐1) is a peptide with pro‐hypertrophic and anti‐apoptotic actions. The pro‐hypertrophic properties of IGF‐1 have been attributed to the extracellular regulated kinase (ERK) ...
    • Role of Human Papillomavirus in Penile Carcinomas Worldwide 
      Alemany, Laia; Cubilla, Antonio; Halec, Gordana; Kasamatsu, Elena; Quiros, Beatriz; Masferrer, Emili; Tous, Sara; Lloveras, Belén; Hernández Suárez, Gustavo; Lonsdale, Ray; Tinoco, Leopoldo; Alejo, María; Alvarado Cabrero, Isabel; Laco, Jan; Guimera, Nuria; Poblet, Enrique; Lombardi, Luis E.; Bergeron, Christine; Clavero, Omar; Shin, Hai-Rim; Ferrera, Annabelle; Félix, Ana; Germar, Julieta; Mandys, Vaclav; Clavel, Christine; Tzardi, María; Pons, Luis E.; Wain, Vincent; Cruz, Eugenia; Molina, Carla; Mota, José D.; Jach, Robert; Velasco, Julio; Carrilho, Carla; López Revilla, Rubén; Goodman, Marc T.; Quint, Wim G.; Castellsague, Xavier; Bravo, Ignacio; Pawlita, Michael; Muñoz, Nubia; Bosch, F. Xavier; de Sanjose, Silvia (Elsevier, 2016)
      Background: Invasive penile cancer is a rare disease with an approximately 22 000 cases per year. The incidence is higher in less developed countries, where penile cancer can account for up to 10% of cancers among men in ...
    • Role of KCTD5 during Helicobacter pylori infection in gastric epithelial cells 
      Toledo Araya, Héctor; Alvarez A., José Miguel; Uribe, F.; Canales, J.; Canto, N.; Cerda Arancibia, Óscar (Wiley, 2017)
    • Role of matrix metalloproteinases 2 and 9 in ex vivo Trypanosoma cruzi infection of human placental chorionic villi 
      Castillo, C.; López-Muñoz, R.; Duaso, J.; Galanti Garrone, Norbel; Jaña, F.; Ferreira, J.; Cabrera, G.; Maya Arango, Juan; Kemmerling Weis, Ulrike (2012)
      Background: Chagas' disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi). During congenital transmission the parasite breaks down the placental barrier. In the present study we analyzed the ...
    • Role of microRNA-23b in epithelial ovarian cancer and its regulation by nerve growth factor 
      Romero Osses, Carmen; Hernández, Andrea; Cuevas, Paula; Retamales, Rocio; Vera, Carolina; Vega Blanco, María Margarita (Spandidos Publications Ltd., 2017)
    • Role of MNS1 in cilia motility during zebrafish development 
      Pulgar Pulgar, Eduardo; Concha Nordemann, Miguel (Elsevier, 2017-07)
    • Role of nerve growth factor (NGF) and miRNAs in epithelial ovarian cancer 
      Retamales-Ortega, Rocío; Oróstica Arévalo, María Lorena; Vera, Carolina; Cuevas, Paula; Hernández, Andrea; Hurtado, Iván; Vega Blanco, María Margarita; Romero Osses, Carmen (MDPI AG, 2017)
      © 2017 by the authors. Licensee MDPI, Basel, Switzerland. Ovarian cancer is the eighth most common cancer in women worldwide, and epithelial ovarian cancer (EOC) represents 90% of cases. Nerve growth factor (NGF) and its ...
    • Role of Neutralizing Antibodies in Adults With Community-Acquired Pneumonia by Respiratory Syncytial Virus 
      Luchsinger Farías, Vivian; Piedra, Pedro A.; Ruiz, Mauricio; Zunino, Enna; Martínez, María Angélica; Machado, Clarisse; Fasce, Rodrigo; Ulloa Flores, María Teresa; Fink, María Cristina; Lara, Pamela; Avendaño, Luis F. (2012-04)
      Background. Respiratory syncytial virus (RSV) has been implicated in the etiology of adult communityacquired pneumonia (CAP). We investigated RSV infection in Chilean adults with CAP using direct viral detection, real-time ...
    • Role of nitric oxide and bcl-2 family genes in the regulation of human endometrial apoptosis 
      Castro, Andrea; Johnson, María Cecilia; Anido, Mabel; Cortinez, Armando; Gabler Neale, Fernando; Vega Blanco, María Margarita (2002)
      Objective: To investigate the role of nitric oxide (NO) and death regulatory genes, bcl-2 and bax, in human endometria apoptosis.Design: Expression of bcl-2, bax, NO synthases (NOS), and the apoptotic effect of L-arginine ...
    • Role of oxidative stress in renal transplantation: bases for an n-3 PUFA strategy against delayed graft function 
      Sotomayor, Camilo; Cortes, Ignacio A.; Gormaz, Juan G.; Vera, Sergio; Libuy, Matías; Valls Jiménez, Nicolás; Rodrigo Salinas, Ramón (Bentham Science Publ Ltd., 2017)
      Renal transplantation (RT) is considered the "gold standard" treatment for end-stage renal disease patients. Efforts should be made to reduce ischaemia-reperfusion (IR) injury, which unavoidably occurs in RT as long as ...