Now showing items 11039-11058 of 11550

    • Sosoniuk, Eduardo; Vallejos, Gerardo; Kenawy, Hany; Gaboriaud, Christine; Thielens, Nicole; Fujita, Teizo; Schwaeble, Wilhelm; Ferreira, Arturo; Valck, Carolina (Elsevier Ltd, 2014)
      Trypanosoma cruzi, the agent of Chagas' disease, the sixth neglected tropical disease worldwide, infects 10-12 million people in Latin America. Differently from T. cruzi epimastigotes, trypomastigotes are complement-resistant ...
    • Sosoniuk Roche, Eduardo Rodrigo; Vallejos, Gerardo; Kenawy, Hany; Gaboriaud, Christine; Thielens, Nicole; Fujita, Teizo; Schwaeble, Wilhelm; Ferreira Vigouroux, Luis Arturo; Valck Calderón, Carolina Eliana (Elsevier, 2014)
      Trypanosoma cruzi, the agent of Chagas’ disease, the sixth neglected tropical disease worldwide, infects10–12 million people in Latin America. Differently from T. cruzi epimastigotes, trypomastigotes arecomplement-resistant ...
    • Ramírez Toloza, Galia; Valck, Carolina; Molina, María C.; Ribeiro, Carolina Hager; López, Nandy; Sánchez, Gittith; Ferreira, Viviana P.; Billetta, Rosario; Aguilar, Lorena; Maldonado, Ismael; Cattan Ayala, Pedro; Schwaeble, Wilhelm; Ferreira Vigouroux, Luis Arturo (Elsevier, 2011)
      In Trypanosoma cruzi, calreticulin (TcCRT) translocates from the endoplasmic reticulum (ER) to the area of flagellum emergence. We propose herein that the parasite uses this molecule to capture complement C1, in an ...
    • Ribeiro, Carolina Hager; López, Nandy C.; Ramírez, Galia A.; Valck, Carolina E.; Molina, María Carmen; Aguilar, Lorena; Rodríguez, Margarita; Maldonado, Ismael; Martínez, Ramón; González, Carlos; Troncoso, Rodrigo; Lavandero González, Sergio; Gingras, Alexandre R.; Schwaeble, Wilhelm (2009)
      Trypanosoma cruzi (T. cruzi) is the causative agent of Chagas' disease, an endemic and chronic illness that affects 18 million people in Latin America. The mechanisms underlying its pathogenesis are controversial. There ...
    • Cruz, P.; Sosoniuk Roche, E.; Maldonado, I.; Torres Mendoza, Cristián G.; Ferreira, A. (Elsevier, 2020)
      Recombinant calreticulin from Trypanosoma cruzi (rTcCalr), the parasite responsible for Chagas' disease, binds to Canine Transmissible Venereal Tumor (CTVT) cells from primary cultures and to a canine mammary carcinoma ...
    • Sánchez Valdéz, Fernando J.; Pérez Brandán, Cecilia; Zago, M. Paola; Labriola, Carlos; Ferreira, Arturo; Basombrío, Miguel Ángel (2013-03)
      Trypanosoma cruzi calreticulin (TcCRT) can hijack complement C1, mannan-binding lectin and ficolins from serum thus inhibiting the classical and lectin complement pathway activation respectively. To understand the in ...
    • Ortiz, S.; Ceballos, M. J.; González, C. R.; Reyes, C.; Gómez, V.; Martínez García, A.; Solari Illescas, Aldo (Elsevier B.V., 2016)
      © 2016 Elsevier B.V. As part of a multi-site research program on the eco-epidemiology and control of Chagas disease in northern Chile, we sought to identify the Trypanosoma cruzi discrete typing units (DTUs) infecting rural ...
    • Arenas, Marco; Campos, Ricardo; Coronado, Ximena; Ortiz, Sylvia; Solari Illescas, Aldo (MARY ANN LIEBERT INC, 2012-03)
      Fifty-six Trypanosoma cruzi stocks from Chile and neighboring countries and different hosts, humans, and Triatoma infestans and Mepraia sp., vectors of domiciliary and natural environments were characterized by using three ...
    • Cura, Carolina I.; Mejía-Jaramillo, Ana M.; Duffy, Tomás; Burgos, Juan M.; Rodriguero, Marcela; Cardinal, Marta V.; Kjos, Sonia; Gurgel-Gonçalves, Rodrigo; Blanchet, Denis; De Pablos, Luis M.; Tomasini, Nicolás; da Silva, Alexandre; Russomando, Graciela; Cuba, Cesar A (2010)
      The intergenic region of spliced-leader (SL-IR) genes from 105 Trypanosoma cruzi I (Tc I) infected biological samples, culture isolates and stocks from 11 endemic countries, from Argentina to the USA were characterised, ...
    • Liempi Manquel, Ana; Droguett Ossa, Daniel; Castillo, Christian; Gómez, Fresia; Negrete, Miguel; Carrillo, Ileana; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (Elsevier, 2015)
    • Duaso, J.; Rojo, G.; Jaña, F.; Galanti Garrone, Norbel; Cabrera, G.; Bosco, C.; López Muñoz, Rodrigo; Maya Arango, Juan; Ferreira, J.; Kemmerling Weis, Ulrike (2011)
      Chagas' disease, produced by the haemoflagellated protozoan Trypanosoma cruzi (T. cruzi), is one of the most frequent endemic diseases in Latin America. In spite that in the past few years T. cruzi congenital transmission ...
    • Droguett, Daniel; Carrillo, Ileana; Castillo, Christian; Gómez, Fresia; Negrete, Miguel; Liempi, Ana; Muñoz, Lorena; Kemmerling Weis, Ulrike; Galanti Garrone, Norbel; Maya Arango, Juan; Droguett, Daniel (Academic Press Inc., 2017)
      © 2016 Elsevier Inc.Congenital transmission of Trypanosoma cruzi (T. cruzi) is partially responsible for the progressive globalization of Chagas disease. During congenital transmission the parasite must cross the placental ...
    • Duaso, J.; Rojo, G.; Cabrera, G.; Galanti Garrone, Norbel; Bosco, C.; Maya Arango, Juan; Morello Casté, Antonio; Kemmerling Weis, Ulrike (Elsevier, 2010)
      Congenital Chagas’ disease, endemic in Latin America and also present with lower frequency in other countries, is associated with premature labor, miscarriage, and placentitis. The mechanism of tissue invasion and infection ...
    • Liempi, A.; Castillo, C.; Duaso, J.; Droguett, D.; Sandoval, A.; Barahona, K.; Hernández, A.; Galanti Garrone, Norbel; Maya Arango, Juan; Kemmerling Weis, Ulrike (W.B. Saunders, 2014)
      Introduction: The congenital transmission of Trypanosoma cruzi (T. cruzi) is responsible for one-third of new Chagas disease cases each year. During congenital transmission, the parasite breaks down the placental barrier ...
    • Cortés, Valeria; Cruz, Amalia; Onetti, Sofía; Kinzel, Daniela; García, Javiera; Ortiz, Sylvia; López, Angélica; Cattan Ayala, Pedro Eduardo; Botto Mahan, Carezza Verónica; Solari Illescas, Aldo Gerónimo (Public Library Science, 2021)
      Chagas disease is caused by Trypanosoma cruzi and transmitted by the triatomine Mepraia spinolai in the southwest of South America. Here, we examined the T. cruzi-infection dynamics of field-caught M. spinolai after ...
    • Egaña, Camila; Vergara, Fernanda; Campos, Ricardo; Ortiz, Sylvia; Botto Mahan, Carezza; Solari Illescas, Aldo (American Society of Tropical Medicine and Hygiene, 2014)
      © 2014 by The American Society of Tropical Medicine and Hygiene. We evaluated Trypanosoma cruzi infection rates by means of minicircle DNA-based polymerase chain reactions (PCRs) in 70 starved Mepraia gajardoi from northern ...
    • Liempi, Ana; Castillo, Christian; Cerda, Mauricio; Droguett, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)
      Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study the physiopathology ...
    • Liempi Manquel, Ana; Castillo, Christian; Cerda Villablanca, Mauricio; Droguett Ossa, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)
      Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study the physiopathology ...
    • Macina, Roberto A.; Arauzo, Silvia; Reyes, Maria B.; Sanchez, Daniel O.; Basombrio, Miguel A.; Montamat, Enrique E.; Solari Illescas, Aldo; Frasch, Alberto C.C. (1987)
      Fifty-two isolates and several clones from Trypanosoma cruzi, the agent of Chagas' disease, were analyzed using cloned minicircles or total kinetoplast DNA as probes. Isolates were obtained from triatomines, guinea pigs ...
    • De Winne, Koen; Büscher, Philippe; Luquetti, Alejandro O.; Tavares, Suelene B. N.; Oliveira, Rodrigo A.; Solari Illescas, Aldo; Zulantay Alfaro, Inés; Apt Baruch, Werner; Diosque, Patricio; Monje Rumi, Mercedes; Girones, Nuria; Fresno, Manuel; López Vélez, Rogelio; Pérez Molina, José A.; Monge Maillo, Begoña; García, Lineth; Deborggraeve, Stijn (2014)
      Background: The Trypanosoma cruzi satellite DNA (satDNA) OligoC-TesT is a standardised PCR format for diagnosis of Chagas disease. The sensitivity of the test is lower for discrete typing unit (DTU) TcI than for TcII-VI ...