Now showing items 6069-6088 of 11550

    • Rogers Castillo, Nicole K.; Romero, César A.; San Martín Rovirosa, Carol D.; Ponce, Daniela P.; Salech Morales, Felipe; López, Mercedes N; Gleisner, Alejandra; Tempio Sepúlveda, Fabián; Behrens Pellegrino, María I. (IOS Press, 2020)
      Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the adult population. There is evidence of an inverse epidemiological relationship between AD and cancer, another prevalent age-related disease. ...
    • Behrens Pellegrino, María Isabel; Silva, Monica; Salech Morales, Felipe; Ponce, Daniela P.; Merino, Daniela; Sinning, Mariana; Xiong, Chengjie; Roe, Catherine M.; Quest, Andrew F. G. (2012)
      A paucity of cancer in individuals with Alzheimer's disease (AD) and low rates of AD in cancer survivors has been reported in epidemiological studies. Deregulation in opposite directions of biological mechanisms, such as ...
    • Buiatti, Marco; Peña, Marcela; Dehaene-Lambertz, Ghislaine (2009)
      In order to learn an oral language, humans have to discover words from a continuous signal. Streams of artificial monotonous speech can be readily segmented based on the statistical analysis of the syllables' distribution. ...
    • Xi, Zhengrui; Zinman, Lorne; Grinberg, Yakov; Moreno, Danielle; Sato, Christine; Bilbao, Juan M.; Ghani, Mahdi; Hernańdez, Isabel; Ruiz, Agustín; Boada, Mercè; Morón, Francisco J.; Lang, Anthony E.; Marras, Connie; Bruni, Amalia; Colao, Rosanna; Maletta, Raffaele G.; Puccio, Gianfranco; Rainero, Innocenzo; Pinessi, Lorenzo; Galimberti, Daniela; Morrison, Karen E.; Moorby, Catriona; Stockton, Joanne D.; Masellis, Mario; Black, Sandra E.; Hazrati, Lili-Naz; Liang, Yan; Haersma de With, Jan van; Fornazzari, Luis; Villagra, Roque; Rojas-Garcia, Ricardo; Clarimón, Jordi; Mayeux, Richard; Robertson, Janice; St George-Hyslop, Peter; Rogaeva, Ekaterina (2012)
      Objective: To estimate the allele frequency of C9orf72 (G4C 2) repeats in amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), Alzheimer disease (AD), and Parkinson disease (PD). Design: The number ...
    • Turner, Andrew D.; Dhanji-Rapkova, Monika; Algoet, Myriam; Suárez Isla, Benjamín; Córdova, Marco; Cáceres, Catherine; Murphy, Cory J.; Casey, Melanie; Lees, David N. (Elsevier, 2012)
      Significant differences previously observed in the determination of paralytic shellfish poisoning toxins (PSTs) in oysters using official method AOAC 2005.06 and 959.08 were investigated in detail with regard to possible ...
    • Guivernau, Mauricio; Quintanilla González, María Elena; Tampier de Jong, Lutske (1994)
      Disulfiram, an aldehyde dehydrogenase (ALDH) inhibitor, induces a flushing reaction upon the ingestion of ethanol, exerting aversion against alcohol that has been used in the treatment of alcoholism. This unpleasant response ...
    • Csendes Juhasz, Attila (Springer-Verlag, 1988)
    • Csendes Juhasz, Attila (Springer-Verlag, 1993)
    • Rodríguez, Juan Pablo; Astudillo, Pablo; Ríos, Susana; Pino, Ana María (2008)
      Mesenchymal Stem Cells (MSCs) from bone marrow stroma are capable of differentiating into osteoblasts and adipocytes, among other cell phenotypes. In normal bone marrow osteoblastic and adipocytic cell differentiation occur ...
    • Marvasi, Massimiliano; Casillas Santiago, Lianne M.; Henríquez, Tania; Casillas Martínez, Lilliam (Taylor & Francis, 2017)
      The eftA gene in Bacillus subtilis has been suggested to be involved in the oxidation/reduction reactions during fatty acid metabolism. Interestingly etfA deletion in B. subtilis results in impairment in CaCO3 precipitation ...
    • Fernández, Virginia; Reyes, Solange; Bravo, Sergio; Sepúlveda, Rodrigo; Romanque, Pamela; Santander, Gonzalo; Castillo, Iván; Varela, Patricia; Tapia, Gladys; Videla Cabrera, Luis (2007)
      Thyroid hormone-induced calorigenesis triggers liver oxidative stress with concomitant TNF-α production by Kupffer cells and up-regulation of gene expression. Considering that cyclin-dependent kinase-2 (CDK-2) performs ...
    • Lara Peñaloza, Hernán; McDonald, John K.; Ojeda, Sergio R. (1990)
      The ovary is innervated by noradrenergic and peptidergic fibers. Treatment of neonatal rats with antibodies to nerve growth factor (NGF Ab) resulted in failure of the sympathetic (noradrenergic and neuropeptide-Y) nerves ...
    • Miranda, Hugo; Sierralta, Fernando; Lux, Sebastian; Troncoso, Rocío; Ciudad, Natalia; Zepeda Iriarte, Ramiro; Zanetta, Pilar; Noriega, Viviana; Prieto, Juan Carlos (Elsevier, 2015)
      Background: Pain is one of the most common problems in clinical medicine. There is considerable evidence that pharmacologic approaches are the most widely used therapeutic options to ameliorate persistent or chronic pain. ...
    • Noriega Sepúlveda, Viviana; Miranda Guzmán, Hugo; Prieto Domínguez, Juan Carlos; Sotomayor Zárate, Ramón; Sierralta García, Fernando (Thieme, 2020)
      There are different animal models to evaluate pain among them the formalin hind paw assay which is widely used since some of its events appear to be similar to the clinical pain of humans. The assay in which a dilute ...
    • Adasme, Tatiana; Haeger, Paola; Paula Lima, Andrea; Espinoza, Italo; Casas-Alarcón, M. Mercedes; Carrasco Friz, María Angélica; Hidalgo Tapia, María Cecilia (NATL ACAD SCIENCES, 2011-02-15)
      Ryanodine receptors (RyR)amplify activity-dependent calciuminflux via calcium-induced calcium release. Calcium signals trigger postsynaptic pathways in hippocampal neurons that underlie synaptic plasticity, learning, ...
    • Kwon, Yoon Jeoung; Pérez, Paola; Aguilera, Sergio; Molina, Claudio; Leyton Campos, Lisette; Alliende, Cecilia; Leyton, Cecilia; Brito, Mónica; Romo, Rafael; González Burgos, María Julieta (2006)
      Objective. To investigate remodeling of the basal lamina of labial salivary glands (LSGs) from patients with Sjögren's syndrome (SS) by analyzing the expression of specific components that participate in its assembly and ...
    • Page, Jesús; Viera, Alberto; Parra, María Teresa; Fuente, Roberto de la; Suja, José Angel; Prieto, Ignacio; Barbero, José Luis; Rufas, Julio S.; Berríos del Solar, María Soledad; Fernández Donoso, Raúl (PUBLIC LIBRARY SCIENCE, 2006-08)
      Marsupial sex chromosomes break the rule that recombination during first meiotic prophase is necessary to ensure reductional segregation during first meiotic division. It is widely accepted that in marsupials X and Y ...
    • Lizama, Carlos; Rojas Benitez, Diego; Antonelli Anativia, Juan; Ludwig, Andreas; Moreno, Ricardo D. (WILEY-BLACKWELL, 2012-02)
      Germ cell apoptosis is important to regulate sperm production in the mammalian testis, but the molecular mechanisms underlying apoptosis are still poorly understood. We have recently shown that in vitro, etoposide induces ...
    • Cruz San Martín, Gabriela Paz; Burgos Concha, Pablo; Kilborn, Kerry; Evans, Jonathan J. (Public Library Science, 2017)
      Objective Time-based prospective memory (PM), remembering to do something at a particular moment in the future, is considered to depend upon self-initiated strategic monitoring, involving a retrieval mode (sustained ...
    • González Ramos, Reinaldo; Van Langendonckt, Anne; Defrre, Sylvie; Lousse, Jean Christophe; Colette, Sebastien; Devoto, Luigi; Donnez, Jacques (2010)
      Objective: To evaluate the role of nuclear factor-κB (NF-κB) in the pathogenesis of endometriosis. Design: A literature search was conducted in PubMed to identify all relevant citations. Result(s): Our findings highlight ...