Now showing items 94-113 of 11551

    • Ponce, Iván; Aldunate, Carmen; Valenzuela, Lucía; Sepúlveda Contreras, Sofía; Garrido, Gilda; Kemmerling Weis, Ulrike; Cabrera Vallejos, Gonzalo; Galanti Garrone, Norbel (Wiley, 2017)
      FLAP endonucleases (FEN) are involved both in DNA replication and repair by processing DNA intermediaries presenting a nucleotide flap using its phosphodiesterase activity. In spite of these important functions in DNA ...
    • Espinoza,; Kramer,; Saavedra Saavedra, Iván; Biagini, (1991)
      The correct clinical use of drug plasma levels is frequently jeopardized by neglecting to consider pharmacokinetic parameters at the time of sample drawing. A form to be filled at this time revealed that inadequate information ...
    • San Martin, B. V.; Pizarro Aránguiz, Nicolás Javier; García Mendoza, Diego Tomás; Araya-Jordán, Carolina; Maddaleno Toledo, Aldo; Abad, E.; Galbán-Malagón, C. J. (Elsevier B.V., 2016)
      © 2016 Elsevier B.V.For the first time in South America, a four-year survey (2011–2014) was conducted to assess the occurrence of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) and dioxin-like polychlorinated ...
    • Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)
      The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
    • Rodríguez T., Jorge; Hernández Araya, Enrique; Fernández, Ana María (2007)
      Background: It is possible that men consume a higher amount of legal and illegal drugs than women. This can be assessed using the peer methodology, that is an adaptation of the privileged access interviewers (PAI) method ...
    • Rodríguez T., Jorge; Hernández A, Enrique; Fernández, Ana María (2007)
      Background: It is possible that men consume a higher amount of legal and illegal drugs than women. This can be assessed using the peer methodology, that is an adaptation of the privileged access interviewers (PAI) method ...
    • Åslund, Lena; Carlsson, Lars; Henriksson, Jan; Rydåker, Maria; Cecilia Toro, G.; Galanti Garrone, Norbel; Pettersson, Ulf (1994)
      A gene family encoding a set of histone H1 proteins in Trypanosoma cruzi is described. The sequence of 3 genomic and 4 cDNA clones revealed the presence of several motifs characteristic of histone H1 although heterogeneity ...
    • DeLisi, Lynn E.; Shaw, Sarah H.; Crow, Timothy J.; Shields, Gail; Smith, Angela B.; Larach, Veronica W.; Wellman, Nigel; Loftus, Josephine; Nanthakumar, Betsy; Razi, Kamran; Stewart, John; Comazzi, Margherita; Vita, Antonio; Heffner, Thomas; Sherrington, Robin (American Psychiatric Association, 2002)
      Objective: Some genome-wide scans and association studies for schizophrenia susceptibility genes have yielded significant positive findings, but there is disagreement between studies on their locations, and no mutation has ...
    • Macías, Francisco; Pérez López, Rafael; Caraballo Monge, Manuel; Sarmiento, M.; Cánovas, Carlos R.; Nieto, Jose M.; Olías, Manuel; Ayora, Carlos (Springer Verlag, 2017)
      © 2016, Springer-Verlag Berlin Heidelberg. The Odiel River Basin (SW Spain) drains the central part of the Iberian Pyrite Belt (IPB), a world-class example of sulfide mining district and concomitantly of acid mine drainage ...
    • Prusakov, Pavel; Goff, Debra A.; Wozniak, Phillip S.; Cassim, Azraa; Scipion, Catherine E. A.; Urzúa, Soledad; Ronchi, Andrea; Zeng, Lingkong; Ladipo Ajayi, Oluwaseun; Avilés Otero, Noelia; Udeigwe Okeke, Chisom R.; Melamed, Rimma; Silveira, Rita C.; Auriti, Cinzia; Beltrán Arroyave, Claudia; Zamora Flores, Elena; Sánchez Codez, María; Donkor, Eric S.; Kekomäki, Satu; Mainini, Nicoletta; Vivas Trochez, Rosalba; Casey, Jamalyn; Graus, Juan M.; Muller, Mallory; Singh, Sara; Loeffen, Yvette; Tamayo Pérez, María Eulalia; Ferreyra, Gloria Isabel; Lima Rogel, Victoria; Perrone, Bárbara; Izquierdo Copiz, Giannina; Cernada, María; Stoffella, Sylvia; Okwuchukwu Ekenze, Sebastián; Alba Romero, Concepción de; Tzialla, Chryssoula; Pham, Jennifer T.; Hosoi, Kenichiro; Calero Consuegra, Magdalena Cecilia; Betta, Pasqua; Hoyos, O. ALvaro; Roilides, Emmanuel; Naranjo Zúñiga, Gabriela; Oshiro, Makoto; Garay, Víctor; Mondì, Vito; Mazzeo, Danila; Stahl, James A.; Cantey, Joseph B.; Mesa Monsalve, Juan Gonzalo; Normann, Erik; Landgrave, Lindsay C.; Mazouri, Ali; Alarcón Ávila, Claudia; Piersigilli, Fiammetta; Trujillo, Mónica; Kolman, Sonya; Delgado, Verónica; Guzmán, Verónica; Abdellatif, Mohamed; Monterrosa, Luis; Gabriella Tina, Lucia; Yunis, Khalid; Belzu Rodríguez, Marco Antonio; Le Saux, Nicole; Leonardi, Valentina; Porta, Alessandro; Latorre, Giuseppe; Nakanishi, Hidehiko; Meir, Michal; Manzoni, Paolo; Norero, Ximena; Hoyos, Ángela; Arias, Diana; García Sánchez, Rubén; Medoro, Alexandra K.; Sánchez, Pablo J. (Elsevier, 2021)
      Background: Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods: We conducted a one-day global point prevalence ...
    • Swedlow, Jason R.; Kankaanpää, Pasi; Sarkans, Ugis; Goscinski, Wojtek; Galloway, Graham; Malacrida, Leonel; Sullivan, Ryan P.; Hartel, Steffen; Brown, Claire M.; Wood, Christopher; Keppler, Antje; Paina, Federica; Loos, Ben; Zullino, Sara; Livio Longo, Dario; Aime, Silvio; Onami, Shuichi (Nature, 2021)
      Imaging technologies are used throughout the life and biomedical sciences to understand mechanisms in biology and diagnosis and therapy in animal and human medicine. We present criteria for globally applicable guidelines ...
    • Soto, M.Angélica; JoséTohá, M.Angélica (1985)
      A quantitative rationale for the evolution of the genetic code is developed considering the principle of minimal hardware. This principle defines an optimal code as one that minimizes for a given amount of information ...
    • Carreño, J.; Vyhmeister, G.; Grau, L.; Ivanovic, D. (2006)
      Objective: In the last decades, the epidemiological and demographic transition in Chile has resulted in a considerable increase in diet-related non-communicable chronic diseases. The aim of this study was to determine the ...
    • Gleisner Muñoz, María Alejandra; Pereda Ramos, Cristián; Tittarelli Elaskar, Andrés; Navarrete Sánchez, Mariela; Fuentes Villegas, Camila; Ávalos, Ignacio; Tempio Sepúlveda, Fabián; Araya, Juan Pablo; Becker, María Inés; González Bergas, Fermín; López Nitsche, Mercedes; Salazar Onfray, Flavio (BMJ, 2020)
      Background Immune checkpoint blocker (ICB) therapy has shown survival benefits for some patients with cancer. Nevertheless, many individuals remain refractory or acquire resistance to treatment, motivating the exploration of ...
    • Prado, Arturo (Lippincott Williams & Wilkins, 2018-06)
    • Manterola, Marcia; Page, Jesús; Vasco, Chiara; Berríos, Soledad; Parra, María Teresa; Viera, Alberto; Rufas, Julio S.; Zuccotti, Maurizio; Garagna, Silvia; Fernández Donoso, Raúl (2009)
      Meiosis is a complex type of cell division that involves homologous chromosome pairing, synapsis, recombination, and segregation. When any of these processes is altered, cellular checkpoints arrest meiosis progression and ...
    • Francisca D.P., Constanza S., Valeria V., Paula E. (Sociedad Chilena de Obstetricia y Ginecologia, 2020)
    • Beas, F.; Salinas, A.; Gonzalez, F.; Teran, C.; Szendro, P. (1975)
      A human placental protein previously described is studied in order to expand its biological characterization. Dose response curve of its action on uterine growth of prepuberal mice showed to be a significant logarithmic ...
    • Caviedes Codelia, Raúl; Liberona Leppe, José; Hidalgo Tapia, Jorge; Tascón, Soledad; Salas, Karime; Jaimovich Pérez, Enrique (Elsevier, 1992)
      A cell line (RCMH) in permanent culture was established from surgically removed adult normal human skeletal muscle by exposure to conditioned media obtained from thyroid cells. Cells proliferated indefinitely but displayed ...