Now showing items 11123-11142 of 11162

    • Kane, Andrew D.; Hansell, Jeremy A.; Herrera, Emilio A.; Allison, Beth J.; Niu, Youguo; Brain, Kirsty L.; Kaandorp, Joepe J.; Derks, Jan B.; Giussani, Dino A. (2014)
      Hypoxia is a common challenge to the fetus, promoting a physiological defence to redistribute blood flow towards the brain and away from peripheral circulations. During acute hypoxia, reactive oxygen species (ROS) interact ...
    • Hernández San Martín, M. J.; Vargas Mora, Pablo; Araníbar Durán, Ligia (Elsevier, 2020)
      El xantogranuloma juvenil es un trastorno benigno poco frecuente, que pertenece al amplio grupo de las histiocitosis de células no Langerhans. Se presenta con uno o más nódulos eritematosos o amarillentos, ubicados ...
    • Hetz Flores, Claudio; Glimcher, Laurie H. (2008)
      A unique feature of secretory cells is the proliferation of the endoplasmic reticulum (ER) and Golgi network. The high demand imposed by protein synthesis and folding in secretory cells constitutes an endogenous source of ...
    • Hetz Flores, Claudio; Thielen, Peter; Matus, Soledad; Nassif, Melissa; Court, Felipe; Kiffin, Roberta; Martinez, Gabriela; Cuervo, Ana María; Brown, Robert H.; Glimcher, Laurie H. (2009)
      Mutations in superoxide dismutase-1 (SOD1) cause familial amyotrophic lateral sclerosis (fALS). Recent evidence implicates adaptive responses to endoplasmic reticulum (ER) stress in the disease process via a pathway known ...
    • Matus, Soledad; Nassif, Melissa; Glimcher, Laurie H.; Hetz Flores, Claudio (Taylor and Francis Inc., 2009)
      Endoplasmic reticulum (ER) stress has been extensively described in many protein misfolding disorders including amyotrophic lateral sclerosis (ALS). Adaptation to ER stress is mediated by the activation of an integrated ...
    • Schenone, Hugo (Fundacao Oswaldo Cruz, 1999)
    • Jaimovich Pérez, Enrique; Mattei, César; Liberona Leppe, José; Cárdenas, César; Estrada Hormazábal, Manuel; Barbier, Julien; Debitus, Cécile; Laurent, Dominique; Molgó, Jordi (ELSEVIER SCIENCE BV, 2005-04-11)
      Xestospongin B, a macrocyclic bis-1-oxaquinolizidine alkaloid extracted from the marine sponge Xestospongia exigua, was highly purified and tested for its ability to block inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ ...
    • Bruin, Christiaan de; Mericq, Verónica; Andrew, Shayne F.; Duyvenvoorde, Hermine A. van; Verkaik, Nicole S.; Losekoot, Monique; Porollo, Aleksey; Garcia, Hernán; Kuang, Yi; Hanson, Dan; Clayton, Peter; Gent, Dik C. van; Wit, Jan M.; Hwa, Vivian; Dauber, Andrew (The Endocrine Society, 2015)
      Context: Severe short stature can be caused by defects in numerous biological processes including defects in IGF-1 signaling, centromere function, cell cycle control, and DNA damage repair. Many syndromic causes of short ...
    • Sánchez, Catherine; Vinay, José; Valdevenito Sepúlveda, Raúl; Palma Ceppi, Cristian (Elsevier, 2016)
      Objective: The aim of this study is to determine the prevalence of Y chromosome microdeletions in infertile Chilean men. Material and methods: A group of 102 infertile men with azoospermia or severe oligozoospermia were ...
    • González, Fernando; Méndez, Gonzalo; Navarrete, Daniela (Sociedad Medica de Santiago, 2017)
    • Sanfurgo Villarroel, Julia Pamela; Álvarez, Ana M.; Salvador, Francisco; Chávez, Ana; Wu Hupat, Elba; Contardo, Verónica (Sociedad Chilena de Infectologia, 2016)
      © 2016, Sociedad Chilena de Infectologia. All rights reserved. Introduction: Pediatric antiretroviral therapy (ART), changed the prognosis of the disease, allowing young women infected by vertical transmission (TV) to be ...
    • Melloni, Margherita; Billeke, Pablo; Báez, Sandra; Hesse, Eugenia; De La Fuente, Laura; Forno, Gonzalo; Birba, Agustina; García Cordero, Indira; Serrano, Cecilia; Plastino, Angelo; Slachevsky Chonchol, Andrea; Huepe, David; Sigman, Mariano; Manes, Facundo; García, Adolfo; Sedeno, Lucas; Ibañez, Agustín (Oxford University Press, 2016)
      Recursive social decision-making requires the use of flexible, context-sensitive long-term strategies for negotiation. To succeed in social bargaining, participants' own perspectives must be dynamically integrated with ...
    • Orellana Serradell, Octavio; Alvarado Herrera, Daniela José; Castellon Vera, Enrique; Contreras Muñoz, Héctor (Spandidos Publications Ltd., 2017)
    • Ulloa, Pilar E.; Iturra, Patricia; Neira Roa, Roberto; Araneda, Cristian (2011)
      Zebrafish (Danio rerio) is a common research model in fish studies of toxicology, developmental biology, neurobiology and molecular genetics; it has been proposed as a possible model organism for nutrition and growth studies ...
    • Colombo, Alicia; Reig, Germán; Mione, Marina; Concha, Miguel L. (ELSEVIER, 2006-04)
      BarH (Barhl) genes encode for highly conserved homeodomain-containing transcription factors involved in critical functions during development, including cell fate specification, migration and survival. Here, we report the ...
    • Alaniz, Alberto J.; Bacigalupo, Antonella; Cattan Ayala, Pedro (Sociedad Chilena de Infectología, 2017)
      The Zika virus has raised world alarm in recent years, representing a major public health problem. In this study we evaluated the potential risk of exposure to Zika virus in Chile, associated with the probability of ...
    • Ruz, Manuel; Carrasco, Fernando; Arenas Rojas, Pamela; Codoceo, Juana; Inostroza, Jorge; Basfi-fer Obregón, Karen; Csendes Juhasz, Attila; Papapietro Vallejo, Karin; Pizarro Aguirre, Fernando; Olivares, Manuel; Sian, Lei; Westcott, Jamie L.; Miller, Leland V.; Hambidge, K. Michael; Krebs, Nancy F. (2011)
      Background: Micronutrient deficiencies are common in patients undergoing gastric bypass. The effect of this type of surgery on zinc absorption and zinc status is not well known. Objective: The objective was to evaluate the ...
    • Ruz, Manuel; Codoceo, Juana; Inostroza Escobar, Jorge; Rebolledo Acevedo, Annabella; Krebs, Nancy F.; Westcott, Jamie E.; Sian, Laei; Hambidge, K. Michael (PERGAMON-ELSEVIER SCIENCE, 2005-12)
      The objective was to compare the absorption of zinc from a micronutrient-fortified dried cow's milk, which is part of the Chilean National Complementary Food Program, with that from a standard nonfortified milk. Fortification ...
    • Solomons, Noel W.; Ruz, Manuel (1997)
      This paper reviews research published in recent years concerning the effects of zinc and iron interaction in both animal and humans. The information is discussed with particular emphasis on those situations relevant to the ...
    • Ruz Ortíz, Manuel; Carrasco Naranjo, Fernando; Rojas Mondaca, Pamela; Codoceo, Juana; Inostroza Escobar, Jorge; Basfi-fer Obregón, Karen; Valencia Canessa, Alejandra; Vásquez, Karla; Galgani Fuentes, José; Pérez, Alvaro; López, Gloria; Arredondo Olguín, Miguel; Pérez Bravo, Francisco (The United Nations University, 2013)
      Background: Type 2 diabetes is highly prevalent in populations having high rates of overweight and obesity. It is a chronic condition responsible for long-term severe dysfunction of several organs, including the ...