Browsing by Author "Farías, Jorge G."

Now showing items 1-5 of 5

    • Cellular and molecular mechanisms in the hypoxic tissue: role of HIF-1 and ROS 
      Zepeda, Andrea B.; Pessoa, Adalberto; Castillo, Rodrigo L.; Figueroa, Carolina A.; Pulgar, Víctor M.; Farías, Jorge G. (John Wiley & Sons, 2013)
      Reactive oxygen species such as superoxide anion radicals (O2 ) and hydrogen peroxide (H2O2) have for long time been recognized as undesirable by-products of the oxidative mitochondrial generation of adenosine triphosphate ...
    • Molecular aspects of breast cancer resistance to drugs (Review) 
      Calaf, Gloria M.; Zepeda, Andrea B.; Castillo Peñaloza, Rodrigo; Figueroa, Carolina A.; Arias, Consuelo; Figueroa, Elías; Farías, Jorge G. (Spandidos Publ, 2015)
      Despite continuous advances in the knowledge of breast cancer pathophysiology, this type of neoplasia remains a leading cause of cancer-related death in women worldwide. Carcinogenesis takes a progressive course from ...
    • Omega 3 chronic supplementation attenuates myocardial ischaemia-reperfusion injury through reinforcement ... 
      Castillo, Rodrigo L.; Arias, Consuelo; Farías, Jorge G. (John Wiley & Sons, 2014)
      Currently, controversial clinical data about the protective effects in the consumption of n-3 polyunsaturated fatty acids (PUFAs) in ischaemic heart diseases exist. Improved myocardial resistance to ischaemia-reperfusion ...
    • Tackling ischemic reperfusion injury with the aid of stem cells and tissue engineering 
      Zamorano, Mauricio; Castillo Peñaloza, Rodrigo Luis; Beltran, Jorge F.; Herrera, Lisandra; Farías, Joaquín A.; Antileo, Christian; Aguilar Gallardo, Cristóbal; Pessoa, Adalberto; Calle, Yolanda; Farías, Jorge G. (Frontiers Media, 2021)
      Ischemia is a severe condition in which blood supply, including oxygen (O), to organs and tissues is interrupted and reduced. This is usually due to a clog or blockage in the arteries that feed the affected organ. ...
    • Ω3 supplementation and intermittent hypobaric hypoxia induce cardioprotection enhancing antioxidant mechanisms ... 
      Herrera, Emilio A.; Farías, Jorge G.; González Candia, Alejandro; Short, Stefania E.; Carrasco Pozo, Catalina; Castillo, Rodrigo L. (MDPI, 2015)
      Intermittent hypobaric hypoxia (IH) is linked with oxidative stress, impairing cardiac function. However, early IH also activate cardio-protective mechanisms. Omega 3 fatty acids (Ω3) induce cardioprotection by reducing ...