Browsing by Author "Zamorano, Sebastian"

Now showing items 1-2 of 2

    • BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α 
      Lisbona, Fernanda; Rojas Rivera, Diego; Thielen, Peter; Zamorano, Sebastian; Todd, Derrick; Martinon, Fabio; Glavic Maurer, Álvaro; Kress, Christina; Lin, Jonathan H.; Walter, Peter; Reed, John C.; Glimcher, Laurie H.; Hetz Flores, Claudio (2009)
      Adaptation to endoplasmic reticulum (ER) stress depends on the activation of an integrated signal transduction pathway known as the unfolded protein response (UPR). Bax inhibitor-1 (BI-1) is an evolutionarily conserved ...
    • BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded ... 
      Rodriguez, Diego A.; Zamorano, Sebastian; Lisbona, Fernanda; Rojas Rivera, Diego; Urra, Hery; Cubillos-Ruiz, Juan R.; Armisen Yáñez, Ricardo; Henriquez, Daniel R.; Cheng, Emily; Letek, Michal; Vaisar, Tomas; Irrazabal, Thergiory; González Billault, Christian; Letai, Antho (2012)
      Adaptation to endoplasmic reticulum (ER) stress depends on the activation of the unfolded protein response (UPR) stress sensor inositol-requiring enzyme 1α(IRE1α), which functions as an endoribonuclease that splices the ...