Browsing by Subject "BDNF"

Now showing items 1-4 of 4

    • Calcium release mediated by redox-sensitive RyR2 channels has a central role in hippocampal structural ... 
      More, Jamileth Y.; Bruna, Barbara A.; Lobos, Pedro; Galaz, Jose L.; Figueroa, Paula L.; Namias, Silvia; Sánchez, Gina; Barrientos Briones, Genaro; Valdes Guerrero, Jose; Paula Lima, Andrea; Hidalgo Tapia, María Cecilia; Adasme, Tatiana (Mary Ann Liebert Inc publishers, 2018)
      Aims: Previous studies indicate that hippocampal synaptic plasticity and spatial memory processes entail calcium release from intracellular stores mediated by ryanodine receptor (RyR) channels. In particular, RyR-mediated ...
    • Chronic stress induces upregulation of brain-derived neurotrophic factor (BDNF) mRNA and integrin α5 ... 
      Dagnino Subiabre, Alexies; Zepeda-Carreño, Rodrigo; Díaz-Véliz, Gabriela; Taiba Mora, Sergio; Aboitiz, Francisco (2006)
      Chronic stress affects brain areas involved in learning and emotional responses. These alterations have been related with the development of cognitive deficits in major depression. Moreover, stress induces deleterious ...
    • Effects of haloperidol and clozapine on synapse-related gene expression in specific brain regions of male rats 
      Wilmsdorff, Martina von; Manthey, Fabián; Bouvier, Marie Luise; Staehlin, Oliver; Falkai, Peter; Meisenzahl Lechner, Eva; Schmitt, Andrea; Gebicke Haerter, Peter J. (Springer, 2018-09)
      We investigated the effects of clozapine and haloperidol, drugs that are widely used in the treatment of schizophrenia, on gene expression in six cortical and subcortical brain regions of adult rats. Drug treatments started ...
    • Regulation of Memory Formation by the Transcription Factor XBP1 
      Martínez, Gabriela; Vidal, Rene; Mardones, Pablo; Serrano, Felipe; Ardiles, Alvaro; Wirth, Craig; Valdés, Pamela; Thielen, Peter; Schneider, Bernard; Kerr, Bredford; Valdés Guerrero, José; Palacios, Adrián; Inestrosa, Nibaldo; Glimcher, Laurie; Hetz Flores, Claudio (CELL PRESS, 2016)
      Contextual memory formation relies on the induction of new genes in the hippocampus. A polymorphism in the promoter of the transcription factor XBP1 was identified as a risk factor for Alzheimer's disease and bipolar ...