Browsing by Subject "Calcium signaling"

Now showing items 1-5 of 5

    • A dorsal root ganglia cell line derived from trisomy 16 fetal mice, a model for Down syndrome 
      Allen, David D.; Cárdenas, Ana María; Arriagada, Christian; Bennett, Lori B.; García, Carlos J.; Caviedes, Ral; Rapoport, Stanley I.; Caviedes, Pablo (Lippincott Williams and Wilkins, 2002)
      We have established two immortalized cell lines from dorsal root ganglia of normal (G4b) and trisomy 16 mice (GTI), a model for Down syndrome. By immunohistochemistry, both cell lines exhibit neuronal traits and lack glial ...
    • Iron deficiency on neuronal function 
      Muñoz, Pablo; Humeres, Alexis (2012)
      Because of the intrinsic ability of iron to catalyze the formation of reactive oxygen species, it has been associated with oxidative stress and neurodegenerative diseases. However, iron deficiency (ID) also negatively ...
    • The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated ... 
      Bruna, Bárbara; Lobos, Pedro; Herrera Molina, Rodrigo; Hidalgo Tapia, María Cecilia; Paula Lima, Andrea; Adasme, Tatiana (Elsevier B.V., 2018)
      © 2018 Elsevier Inc. The neurotrophin Brain-Derived Neurotrophic Factor (BDNF) induces complex neuronal signaling cascades that are critical for the cellular changes underlying synaptic plasticity. These pathways include ...
    • TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the ... 
      Rojas Rivera, Diego; Armisen Yáñez, Ricardo; Colombo, A.; Martínez, G.; Eguiguren, A. L.; Díaz, A.; Kiviluoto, S.; Rodríguez, D.; Patron, M.; Rizzuto, R.; Bultynck, G.; Concha Nordemann, Miguel; Sierralta, J.; Stutzin Schottlander, Andrés; Hetz Flores, Claudio (2012)
      Transmembrane BAX inhibitor motif-containing (TMBIM)-6, also known as BAX-inhibitor 1 (BI-1), is an anti-apoptotic protein that belongs to a putative family of highly conserved and poorly characterized genes. Here we report ...
    • TRP channels interactome as a novel therapeutic target in breast cancer 
      Saldías Maulén, María Paz; Maureira Fuentes, Diego Javier; Orellana Serradell, Octavio Andrés; Silva del Canto, Ian; Lavanderos Andrade, Boris Joan; Cruz, Pablo; Torres Paredes, Camila Esperanza; Cáceres Lluch, Mónica; Cerda Arancibia, Oscar Alejandro (MDPI, 2021)
      Breast cancer is one of the most frequent cancer types worldwide and the first cause of cancer-related deaths in women. Although significant therapeutic advances have been achieved with drugs such as tamoxifen and trastuzumab, ...