Browsing by Subject "Integrins"

Now showing items 1-5 of 5

    • alpha (V) beta (3) Integrin regulates astrocyte reactivity 
      Lagos Cabre, Raúl; Álvarez, Álvaro; Kong, Milene; Burgos Bravo, Francesca; Cárdenas, Areli; Rojas Mancilla, Edgardo; Pérez Núñez, Ramón Daniel; Herrera Molina, Rodrigo; Rojas, Fabiola; Schneider, Pascal; Herrera-Marschitz Muller, Mario; Quest, Andrew F. G.; van Zundert, Brigitte; Leyton Campos, Lisette (BIOMED Central Ltd., 2017)
      Background: Neuroinflammation involves cytokine release, astrocyte reactivity and migration. Neuronal Thy-1 promotes DITNC1 astrocyte migration by engaging alpha(V)beta(3) Integrin and Syndecan-4. Primary astrocytes express ...
    • ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation 
      Henríquez, Mauricio; Herrera Molina, Rodrigo; Valdivia, Alejandra; Alvarez, Alvaro; Kong, Milene; Muñoz, Nicolás; Eisner, Verónica; Jaimovich Pérez, Enrique; Schneider, Pascal; Quest, Andrew F. G.; Leyton Campos, Lisette (2011)
      Thy-1, an abundant mammalian glycoprotein, interacts with avβ3 integrin and syndecan-4 in astrocytes and thus triggers signaling events that involve RhoA and its effector p160ROCK, thereby increasing astrocyte adhesion to ...
    • Lymphocyte adhesion to endothelium derived from human lymphoid tissue 
      Castro, Andrea; Bono Merino, María Rosa; Simon, Valeska; Rosemblatt Silber, Mario César (Elsevier GmbH, 1996)
      The development of an efficient immune response depends on the capacity of antigen-specific lymphocytes to migrate into secondary lymphoid organs. The first step in the process of lymphocyte extravasation involves lymphocyte ...
    • Signaling triggered by Thy-1 interaction with β3 integrin on astrocytes is an essential step towards ... 
      Avalos, Ana Maria; Labra, Cecilia V.; Quest, Andrew F. G.; Leyton Campos, Lisette (2002)
      Thy-1 is an abundant neuronal glycoprotein in mammals. Despite such prevalence, Thy-1 function remains largely obscure in the absence of a defined ligand. Recently described evidence that Thy-1 interacts with β3 integrin ...
    • SPARC induces E-cadherin repression and enhances cell migration through integrin v beta 3 and the transcription ... 
      López Moncada, Fernanda; Torres Torres, María José; Lavanderos Andrade, Boris; Cerda Arancibia, Oscar; Castellón Vera, Enrique; Contreras Muñoz, Héctor (MDPI, 2022)
      Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a matricellular protein that modulates interactions between cells and their microenvironment. SPARC is expressed during extracellular matrix remodeling ...