Browsing by Subject "Lindane"
Now showing items 1-6 of 6
-
(1986)The administration of single i.p. doses of lindane (20, 40, 60 and 80 mg/kg) to rats produced a progressive increase in the liver microsomal content of cytochrome P-450 and in the rate of superoxide anion generation, as ...
-
(2002)The role of Kupffer cells in the hepatocellular injury and oxidative stress induced by lindane (20 mg/kg; 24h) in hyperthyroid rats (daily doses of 0.1 mg L-3,3′,5-triio-dothyronine (T3)/kg for three consecutive days) was ...
-
(2001)The involvement of cytosolic nitric oxide (NO) and mitochondrial superoxide radical (O2 ·-) production was evaluated as a mechanism triggering liver oxidative stress in lindane (40 mg/kg) or L-3,3′,5-triiodothyronine (T3, ...
-
(1989)The effects of lindane administration (25–60 mg kg−1 for 24 h) on hepatic oxygen consumption were studied in the isolated perfused rat liver, in the absence and presence of the iron‐chelator free‐radical scavenger ...
-
(1988)The i.p. administration of 60 mg kg−1 body weight of lindane, the γ‐isomer of hexachlorocyclohexane, to fed rats led to an enhancement of hepatic lipid peroxidation after 24 h of treatment. This was evidenced by significant ...
-
(1993)The administration of lindane (60 mg/kg) to fed rats diminished the content of hepatic glutathione (GSH) 4 h after treatment, which was recovered at 24 h. At these experimental times, the activities of glutathione peroxidase, ...