Browsing by Subject "Localization"

Now showing items 1-3 of 3

    • Axons provide the secretory machinery for trafficking of voltage-gated sodium channels in peripheral nerve 
      González Roca, Carolina; Cánovas, José; Fresno, Javiera; Couve, Eduardo; Court, Felipe A.; Couve Correa, Andrés (National Academy of Sciences, 2016)
      The regulation of the axonal proteome is key to generate and maintain neural function. Fast and slow axoplasmic waves have been known for decades, but alternative mechanisms to control the abundance of axonal proteins based ...
    • Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer 
      Simón, L.; Campos González, América; Leyton Campos, Lisette; Quest, Andrew F. G. (Springer, 2020)
      Caveolin-1 (CAV1) is commonly considered to function as a cell surface protein, for instance in the genesis of caveolae. Nonetheless, it is also present in many intracellular organelles and compartments. The contributions ...
    • Non-conventional axonal organelles control TRPM8 ion channel trafficking and peripheral cold sensing 
      Cornejo, Víctor Hugo; González, Carolina; Campos, Matías; Vargas Saturno, Leslie; Juricic, María de los Ángeles; Miserey Lenkei, Stéphanie; Pertusa, María; Madrid, Rodolfo; Couve, Andrés (Cell Press, 2020)
      TRPM8 is the main ion channel responsible for cold transduction in the somatosensory system. Nerve terminal availability of TRPM8 determines cold sensitivity, but how axonal secretory organelles control channel delivery ...