Browsing by Subject "Neuromuscular junction"

Now showing items 1-4 of 4

    • Botulinum neurotoxin: Evolution from poison, to research tool - Onto medicinal therapeutic and future ... 
      Kostrzewa, Richard M.; Segura Aguilar, Juan (2007)
      Botulinum neurotoxin (BoNT), for more than a hundred years, has been a recognized poisonous principle in spoiled food. As its chemical structure became unraveled, and as more knowledge was gained over its mechanism of ...
    • Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at ... 
      Cheusova, Tatiana; Khan, Muhammad Amir; Schubert, Steffen Wolfgang; Gavin, Anne Claude; Buchou, Thierry; Jacob, Germaine; Sticht, Heinrich; Allende, Jorge E.; Boldyreff, Brigitte; Brenner, Hans Rudolf; Hashemolhosseini, Said (2006)
      The release of Agrin by motoneurons activates the muscle-specific receptor tyrosine kinase (MuSK) as the main organizer of subsynaptic specializations at the neuromuscular junction. MuSK downstream signaling is largely ...
    • Dlg Is required for short-term memory and interacts with NMDAR in the drosophila brain 
      Bertin, Francisca; Moya Alvarado, Guillermo Adrián; Quiroz Manríquez, Eduardo; Ibacache, Andrés; Köhler Solís, Andrés; Oliva, Carlos; Sierralta Jara, Jimena Alejandra (MDPI, 2022)
      The vertebrates’ scaffold proteins of the Dlg-MAGUK family are involved in the recruitment, clustering, and anchoring of glutamate receptors to the postsynaptic density, particularly the NMDA subtype glutamate-receptors ...
    • Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS 
      Rozas Rojas, Pablo Sebastián; Pinto, Cristina; Martínez Traub, Francisca José; Díaz Hinojosa, Rodrigo Ignacio; Pérez, Viviana; Becerra, Daniela; Ojeda, Patricia; Ojeda, Jorge; Wright, Madison T.; Mella, Jéssica; Plate, Lars; Henríquez, Juan Pablo; Hetz Flores, Claudio Andrés; Bilches Medinas, Danilo (BMC, 2021)
      Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice ...