Browsing by Subject "Neuronal cells"

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    • The damage signals hypothesis of Alzheimer's disease pathogenesis 
      Fernández, Jorge A.; Rojo, Leonel; Kuljis, Rodrigo O.; Maccioni Baraona, Ricardo (IOS Press, 2008)
      Virtually none of the hypotheses on Alzheimer's disease (AD) pathogenesis address the earliest events that trigger the molecular alterations that precede cerebral degeneration and account for the diversity of risk factors ...
    • The Revitalized Tau Hypothesis on Alzheimer's Disease 
      Maccioni Baraona, Ricardo; Farías, Gonzalo; Morales, Inelia; Navarrete, Leonardo (2010)
      Many hypotheses have been raised regarding the pathophysiology of Alzheimer's disease (AD). Because amyloid beta peptide (Aβ) deposition in senile plaques appears as a late, nonspecific event, recent evidence points to tau ...