Browsing by Subject "P53"

Now showing items 1-4 of 4

    • Autophagy as a therapeutic target in cardiovascular disease 
      Nemchenko, Andriy; Chiong Lay, Mario; Turer, Aslan; Lavandero González, Sergio; Hill, Joseph A. (2011)
      The epidemic of heart failure continues apace, and development of novel therapies with clinical efficacy has lagged. Now, important insights into the molecular circuitry of cardiovascular autophagy have raised the prospect ...
    • Genetic polymorphisms as non-modifiable susceptibility factors to laryngeal cancer 
      Escalante, Paula; Barría, Tamara; Cancino Castañeda, Miguel; Rahal Espejo, Maritza; Cerpa, Leslie; Sandoval, Christopher; Molina Mellico, Sebastián; Suárez, Marcelo I.; Martínez, Matías; Cáceres Lillo, Dante; Quiñones, Luis Abel; Varela Figueroa, Nelson (Portland Press, 2020)
      Laryngeal squamous cell carcinoma (LSCC) is a highly disabling disease to the patient, affecting speech, swallowing and respiratory skills. Smoking and alcohol abuse are principal risk factors linked to this disease. Genetic ...
    • Malathion affects spermatogenic proliferation in mouse Malathion afecta la proliferación espermatogénica del ratón 
      Penna-Videau, S.; Bustos-Obregón, E.; Cermeño-Vivas, J. R.; Chirino, D. (Universidad de la Frontera, 2012)
      The restriction of the mechanisms of cell proliferation in murine seminiferous epithelium, in terms of induction of programmed cell death until recently has not been fully analyzed. The aim of this work was to assess the ...
    • When Endoplasmic Reticulum Proteostasis Meets the DNA Damage Response 
      González Quiroz, Matías; Blondel, Alice; Sagredo, Alfredo; Hetz Flores, Claudio; Chevet, Eric; Pedeux, Remy (Elsevier, 2020)
      Sustaining both proteome and genome integrity (GI) requires the integration of a wide range of mechanisms and signaling pathways. These comprise, in particular, the unfolded protein response (UPR) and the DNA damage response ...