Now showing items 1-4 of 4

    • Hinzpeter Cohen, Jaime Rodrigo; Barrientos Mendoza, Cristian Nelson; Zamorano Cadenas, Álvaro Igor; Martínez, Álvaro; Palet Bonell, Miguel Jaime Luis; Wulf Ibáñez, Rodrigo Alfonso; Barahona Vásquez, Maximiliano Andrés; Sepúlveda, Joaquín M.; Guerra, Matías; Bustamante, Tamara; Del Campo, Miguel; Tapia, Eric; Lagos, Néstor (Pergamon-Elsevier Science Ltd., 2016)
      Improvements in pain management techniques in the last decade have had a major impact on the practice of total knee arthroplasty (TKA). Gonyautoxin are phycotoxins, whose molecular mechanism of action is a reversible block ...
    • Vásquez, Mónica; Grüttner, Carol; Möeller, Blanca; Moore, Edward R.B. (2002)
      Paralytic shellfish toxins (PSTs) are sodium channel blocking (SCB) toxins, produced by cyanobacteria, as well as by marine dinoflagellates and their associated bacteria, and cause serious health and economic concern ...
    • Galindo, J.; Contreras, M.; Maldonado, P.; Torrealba, F.; Lagos, N.; Valdés, J. L. (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Background: Neosaxitoxin (NeoSTX) and related paralytics shellfish toxins has been successfully used as local anesthetic and muscle relaxants to treat a variety of ailments. The primary mechanism of ...
    • Riquelme, Gricel; Sepúlveda, Joaquín M.; Ghumgham, Zaki Al; Campo, Miguel del; Montero, Cecilia; Lagos, Néstor (Pergamon-Elsevier Science LTD, 2018)
      Local anesthesia is an effective method to control pain. Neosaxitoxin is a phycotoxin whose molecular mechanism includes a reversible inhibition of voltage gated sodium channels at the axonal level, impeding nerve impulse ...