Browsing by Subject "Regulatory T cells"

Now showing items 1-6 of 6

    • A synthetic peptide homologous to IL-10 functional domain induces monocyte differentiation to TGF-β+ ... 
      López, Mercedes N.; Pesce Reyes, Bárbara; Kurte, Mónica; Pérez Núñez, Claudio; Segal, Gabriela; Roa, Johanna; Aguillón Gutiérrez, Juan Carlos; Mendoza Naranjo, Ariadna; Gesser, Borbala; Larsen, Christian; Villablanca, Andrea; Choudhury, Aniruddha; Kiessling, Rolf; Salazar Onfray, Flavio (2011)
      We have previously demonstrated that IT9302, a nonameric peptide homologous to the C-terminal domain of human IL-10, mimics several effects of the cytokine including down-regulation of the antigen presentation machinery ...
    • Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands ... 
      Aravena, Octavio; Pesce Reyes, Bárbara; Soto, Lilian; Orrego, Natalia; Sabugo, Francisca; Wurmann, Pamela; Molina, María Carmen; Alfaro, Jorge; Cuchacovich Turteltaub, Miguel; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (2011)
      The aim of this work was to study the effect of anti-TNF treatment on CD4+ Th1, Th17 and regulatory T cells (Tregs), together with CD8+ T cells and NK cells from rheumatoid arthritis (RA) patients. For this purpose, 18 RA ...
    • Rapamycin-conditioned dendritic cells activated with monophosphoryl lipid-A promote allograft acceptance in vivo 
      Campos Acuña, Javier; Pérez, Francisco; Narváez, Edgar; Campos Mora, Mauricio; Gajardo, Tania; Catalán Martina, Diego; Aguillón Gutiérrez, Juan Carlos; Pino Lagos, Karina (Future Medicine, 2015)
      Aim: To date, there is no human dendritic cell (DC) based therapy to prevent allograft rejection in transplanted patients. Here, we evaluate a potential protocol using a murine in vivo transplant model. Materials & ...
    • Role of dendritic cells in the induction of lymphocyte tolerance 
      Osorio, Fabiola; Fuentes, Camila; López, Mercedes N.; Salazar Onfray, Flavio; González, Fermín E. (Frontiers Media, 2015)
      The ability of dendritic cells (DCs) to trigger tolerance or immunity is dictated by the context in which an antigen is encountered. A large body of evidence indicates that antigen presentation by steady-state DCs induces ...
    • Therapeutic potential of hyporesponsive CD4(+) T cells in autoimmunity 
      Maggi, Jaxaira; Schafer, Carolina; Ubilla Olguín, Gabriela; Catalán Martina, Diego; Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos (Frontiers Media, 2015)
      The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs induce tolerance through T-cell deletion, generation of regulatory T cells, ...
    • Therapeutic potential of hyporesponsive CD4+ T cells in autoimmunity 
      Maggi, Jaxaira; Schafer, Carolina; Ubilla Olguín, Gabriela; Catalán Martina, Diego; Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos (Frontiers Media S.A., 2015)
      © 2015 Maggi, Schafer, Ubilla-Olguín, Catalán, Schinnerling and Aguillón. The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs ...