Now showing items 1-14 of 14

    • Jorge Guzmán, S.; Rodrigo Salinas, Ramón (2012)
      Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disorder of the central nervous system, characterized by an acute or subacute onset of neurological symptoms and focal signs in association with multifocal ...
    • Beltrán, Caroll J.; Núñez, Lucía E.; Díaz Jiménez, David; Farfán, Nancy; Candia, Enzo; Heine, Claudio; López, Francisco; González Burgos, María Julieta; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2010)
      Background: ST2 has been proposed to be a regulator of inflammation and Th1/Th2 balance. ST2L is the IL-33 membrane receptor and belongs to the IL-1R family. The soluble variant, ST2s, is identical to the extracellular ...
    • Núñez Figueroa, Paulina; Quera, Rodrigo; Rubin, David T. (Baishideng Publishing, 2022)
      Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is a chronic immune-mediated inflammatory disease that primarily affects the gastrointestinal tract and is characterized by periods of ...
    • Núñez Figueroa, Paulina Javiera; Cleveland, Noa Krugliak; Quera Pino, Rodrigo Enrique; Rubín, David T. (Baishideng Publishing Group Inc, United States, 2021)
      Inflammatory bowel disease, encompassing Crohn’s disease (CD) and ulcerative colitis, are chronic immune-mediated inflammatory bowel diseases (IBD) that primarily affect the gastrointestinal tract with periods of activity ...
    • Dubois Camacho, Karen; Ottum, Payton A.; Franco Muñoz, Daniel; Fuente, Marjorie de la; Torres Riquelme, Alejandro; Díaz Jiménez, David; Olivares Morales, Mauricio; Astudillo, Gonzalo; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Baishideng Publishing Group, 2017)
      Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are chronic pathologies associated with a deregulated immune response in the intestinal mucosa, and they are triggered by environmental ...
    • Candia, Enzo; Díaz Jiménez, David; Langjahr, Patricia; Núñez, Lucía E.; Fuente, Marjorie de la; Farfán, Nancy; López Kostner, Francisco; Abedrapo Moreira, Mario Antonio; Alvarez Lobos, Manuel; Pinedo, George; Beltrán, Caroll J.; González, Carlos; González Burgos, María Julieta; Quera Pino, Rodrigo (2012)
      Toll-like receptor 2 (TLR2) is a type I pattern recognition receptor that has been shown to participate in intestinal homeostasis. Its increased expression in the lamina propria has been associated with the pathogenesis ...
    • Beltrán, Caroll J.; Candia, Enzo; Erranz, Benjamín; Figueroa, Carolina; Gonzalez, Maria J.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2009)
      Crohn's disease (CD) and ulcerative colitis (UC) belong to the group of inflammatory bowel diseases (IBD), with complex ethiopathogenic factors that include an unbalanced immune and inflammatory response to commensal and ...
    • Núñez Figueroa, Paulina; Quera P., Rodrigo; Gomollón, Fernando (Elsevier, 2019)
      The association between inflammatory bowel disease (IBD) and primary sclerosing cholangitis should be considered a distinct clinical entity. This association involves genetic abnormalities, epidemiological factors (more ...
    • Landskron Ramos, Glauben Tamara; Dubois Camacho, Karen; Orellana Serradell, Octavio Andrés; Fuente López, Majorie de la; Parada Venegas, Daniela Estefani; Bitrán Ambler, Mirit Luisa; Díaz Jiménez, David; Tang, Shuang; Cidlowski, John A.; Li, Xiaoling; Molina, Héctor; González, Carlos M.; Simian, Daniela; Lubascher, Jaime; Pola, Víctor; Montecino, Martín; Blokzijl, Tjasso; Faber, Klaas Nico; González Burgos, María Julieta; Quera, Rodrigo; Hermoso, Marcela Alejandra (MDPI, 2022)
      Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) and can be treated with glucocorticoids (GC), although some patients are unresponsive to this therapy. The transcription factor LRH-1/NR5A2 is critical to ...
    • Pérez de Arce Oñate, Edith; Quera, Rodrigo; Ribeiro Barros, Jaqueline; Sassaki, Ligia Yukie (Dove Medical, 2021)
      Inflammatory bowel disease (IBD) is a chronic condition that globally affects the health of people who suffer from it, deteriorating their quality of life (QoL). An aspect rarely explored by healthcare providers is the ...
    • Díaz Jiménez, David; De la Fuente, Marjorie; Dubois Camacho, Karen; Landskron, Glauben; Fuentes, Janitza; Pérez, Tamara; González Burgos, María Julieta; Simian, Daniela; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2016)
      Background: The ST2/IL-33 pathway has been related to ulcerative colitis (UC), and soluble ST2 (sST2), to disease severity. We tested the potential usefulness of sST2 as a predictive marker of treatment response and patients' ...
    • Díaz Jiménez, David; Núñez, Lucía E.; Beltrán, Caroll J.; Candia, Enzo; Suazo, Cristóbal; Álvarez Lobos, Manuel; González Burgos, María Julieta; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2011)
      AIM: To correlate circulating soluble ST2 (sST2) levels with the severity of ulcerative colitis (UC) and serum levels of pro-inflammatory cytokines, and to demonstrate the predictive power of sST2 levels for differentiation ...
    • Quera, Rodrigo; Flores, Lilian; Núñez Figueroa, Paulina; Ibáñez, Patricio (Sociedad Médica de Santiago, 2020)
      Biological therapy dramatically changed the management of Ulcerative Colitis (UC). However, a significant number of these patients fail to respond or have secondary loss of response to this strategy. In this clinical ...
    • Juliao-Baños, F.; Grillo Ardila, C. F.; Alfaro, I.; Andara Ramírez, M. T.; Avelar Escobar, O.; Barahona Garrido, J.; Bautista Martínez, S.; Bosques Padilla, F. J.; Paula, J. A. de; Ernest-Suárez, K.; Galiano, M. T.; Lade Vergara, B.; Ibáñez, Patricio; Jara Alba, M. L.; Kotze, P. G.; Miranda Ojeda, M. C.; Ortuño Escalante, R.; Otoya Moreno, G.; Piñol Jiménez, F. N.; Ramos Polo, I. C.; Sambuelli, A.; Toro, M.; Torres, E. A.; Veitia Velásquez, G. R.; Yamamoto Furusho, J. K.; Zaltman, C.; Steinwurz, F.; Vallejo Ortega, M.; Torres Castillo, J. I.; Hamon Pinilla, C.; Calderón Franco, C. H.; Escobar Villegas, A. M. (Elsevier, 2022)
      Ulcerative colitis (US) is a chronic disease of unknown etiology. It is incurable and its clinical course is intermittent, characterized by periods of remission and relapse. The prevalence and incidence of the disease has ...