Now showing items 741-760 of 11593

    • Castilho, Jessica L.; Kim, Ahra; Jenkins, Cathy A.; Grinsztejn, Beatriz; Gotuzzo, Eduardo; Fink, Valeria; Padgett, Denis; Belaunzaran Zamudio, Pablo F.; Crabtree Ramírez, Brenda; Escuder, María Mercedes; Souza, Rosa Alencar; Tenore, Simone B.; Pimentel, Sidnei R.; Rodrigues Ikeda, María Leticia; De Alencastro, Paulo R.; Tupinanbas, Unai; Brites, Carlos; Luz, Estela; Netto, Juliana; Cortes, Claudia P.; Grangeiro, Alexandre; Shepherd, Bryan; McGowan, Catherine C. (John Wiley & Sons, 2021)
      Introduction: Kaposi’s sarcoma (KS) remains the most frequent malignancy in persons living with HIV (PWH) in Latin America. We examined KS trends and outcomes from Latin American clinical sites in the era of increased ...
    • Roger, Claire; Louart, Benjamín; Elotmani, Loubna; Barton, Greg; Escobar Oregón, Leslie Dominique; Koulenti, Despoina; Lipman, Jeffrey; Leone, Marc; Muller, Laurent; Boutin, Caroline; Amour, Julien; Banakh, Louri; Cousson, Joel; Bourenne, Jeremy; Constantin, Jean‑Michel; Albanese, Jacques; Roberts, Jason A.; Lefrant, Jean‑Yves (Springer, 2021)
      Background: While aminoglycosides (AG) have been used for decades, debate remains on their optimal dosing strategy. We investigated the international practices of AG usage specifically regarding dosing and therapeutic ...
    • Müller, Bettina; García, Carlos; Sola Aylwin, José Antonio; Fernández, Wanda; Werner, Patrick; Cerda, Mauricio; Slater Morales, Jeannei Ann; Benavides, Carlos; Arancibia, Jorge; Ascui Fernandez, Rodrigo Andres; Reyes, Felipe; Stevens Pinochet, Mary Ann; Miranda, Juan Pablo; Buchholtz Fontova, Martin Lucas; Corvalán, Alejandro H (Cancer Intelligence Ltd, 2021)
      Gastric cancer (GC) is a leading cause of cancer death in Chile. Although recommended in international guidelines since 2006, perioperative chemotherapy was not available to patients in the public health system in Chile ...
    • Coco Martin, Rosa M.; Andrés Iglesias, Cristina; Srivastava, Girish K.; Lagos Rodríguez, Javier; Ruiz Tevah, Miguel; Díaz Cárdenas, Mario R.; Fernández Bueno, Iván; García Serna, Juan; García Gutiérrez, María Teresa; García Layana, Alfredo; Pastor, J. Carlos (Nature Research, 2021)
      Serious intraocular toxicity cases have been reported worldwide after the use of different perfluorocarbon liquids. The current study reports for the first-time the clinical pictures of cases of acute intraocular toxicity ...
    • Álvarez, Matías L.; Waissbluth, Sofía; González, Claudia; Napolitano, Carla; Torrente Avendaño, Mariela Claudia; Délano Reyes, Paul Hinckley; Alarcón, Ricardo; Fernández, Francisco; Bitrán, Roger (Medwave Estudios, 2021)
      Introducción La enfermedad por coronavirus 2019, o COVID-19, se ha convertido en una pandemia. Dada que la mayor carga viral de coronavirus de tipo 2 causante del síndrome respiratorio agudo severo (SARS-CoV-2) se encuentra ...
    • Jackson, Sara S.; Van De Wyngard, Vanessa; Pfeiffer, Ruth M.; Cook, Paz; Hildesheim, Allan; Pinto, Ligia A.; Jackson, Sharon H.; Choi, Kelvin; Verdugo, Ricardo A.; Cuevas, Mara; Yáñez, Cristian; Tobar Calfucoy, Eduardo Andrés; Retamales Ortega, Rocío Mariana; Araya, Juan Carlos; Ferreccio Keadi, Catterina; Koshiol, Jill (Nature Research, 2021)
      Chile has high incidence rates of gallbladder cancer globally, particularly among Amerindian women, who also have a high prevalence of gallstones. We examined differences in inflammatory biomarkers between Mapuche and ...
    • Juri Clavería, Carlos; Kramer, Vasko; Riss, Patrick J.; Soza Ried, Cristian Andres; Haeger Cahuas, Arlette Daniela; Pruzzo, Rossana; Rösch, Frank; Amaral, Horacio; Chana Cuevas, Pedro Francisco (Lippincott Williams & Wilkins, 2021)
      Degeneration of dopaminergic, nigrostriatal neurons is the hallmark of Parkinson disease (PD), and PET quantification of dopamine transporters is a widely accepted method for differential diagnosis between idiopathic ...
    • Torres Castro, Rodrigo Hernán; Gimeno Santos, Elena; Vilaró, Jordi; Roqué Figuls, Marta; Moisés, Jorge; Vasconcello Castillo, Luis Eduardo; Orizaga, Tanya; Barberà, Joan Albert; Blanco, Isabel (European Respiratory Soc Journals Ltd, 2021)
      Background Pulmonary hypertension (PH) is a frequent complication in patients with COPD. Objective To determine if, in patients with COPD, the presence of PH decreases exercise tolerance. Methods We included studies that ...
    • González, Liliana A.; Melo González, Felipe; Sebastián, Valentina P.; Vallejos, Omar P.; Noguera, Loreani P.; Suazo, Isidora D.; Schultz Lombardic, Barbara Melinka; Manosalva, Andrés H.; Peñaloza, Hernán F.; Soto, Jorge A.; Parker, Dane; Riedel, Claudia A.; González, Pablo A.; Kalergis, Alexis M.; Bueno, Susan M. (Frontiers Media, 2021)
      Neutrophils are immune cells classically defined as pro-inflammatory effector cells. However, current accumulated evidence indicates that neutrophils have more versatile immune-modulating properties. During acute lung ...
    • Cisterna, Patricio; Ovalle Salas, Alfredo (Sociedad Chilena de Obstetricia y Ginecología, 2021)
      La actinomicosis pélvica es una infección bacteriana supurativa crónica, producida por especies de Actinomyces, principalmente Actinomyces israelii, que afecta el aparato genital interno y las estructuras vecinas, asociada ...
    • Ovalle Salas, Alfredo; Figueroa, Jorge (Sociedad Chilena de Obstetricia y Ginecología, 2021)
      El parto prematuro es la principal causa de morbilidad y de mortalidad perinatal, y hasta un tercio de los casos presentan rotura prematura de membranas. La infección intrauterina que asciende desde la vagina es su principal ...
    • Ovalle Salas, Alfredo; Kakarieka Weisskopf, Elena (Sociedad Chilena de Infectología, 2021)
      Esta revisión narrativa incluye estudios publicados sobre métodos de clasificación de mortinatos y su eficiencia para identificar la infección bacteriana ascendente (IBA) como causa de muerte fetal (MF), mediante búsqueda ...
    • Wormald, Francisca; Tapia, José L.; Domínguez, Angélica; Cánepa, Paula; Miranda, Ángela; Torres, Gabriela; Rodríguez, Diana; Acha, Leila; Fonseca, Rossana; Ovalle, Natalia; Anchorena, M. Luisa; Danner, Max (Soc Argentina Pediatría, 2021)
      Introduction. There is little evidence regarding the influence of emotional variables on breastfeeding among mothers of very low birth weight infants (VLBWIs). The objective of this study was to measure breast milk ...
    • Valenzuela, Fernando; Flores, Rodrigo (Hospital Clinicas, Brasil, 2021)
      Monoclonal antibodies or fusion proteins, defined as biological drugs, have modified the natural history of numerous immune-mediated disorders, allowing the development of therapies aimed at blocking the pathophysiological ...
    • Evans, Emily P. P.; Scholten, Jorien T. M.; Mzyk, Aldona; Reyes San Martin, Claudia; Llumbet, Arturo; Hamoh, Thamir; Arts, Eus G. J. M.; Schirhagl, Romana; Cantineau, Astrid E. P. (Elsevier, 2021)
      To date 15% of couples are suffering from infertility with 45-50% of males being responsible. With an increase in paternal age as well as various environmental and lifestyle factors worsening these figures are expected to ...
    • Borgonovo, Janina Edith; Ahumada Galleguillos, Patricio Eduardo; Oñate Ponce, Alejandro; Allende Castro, Camilo; Henny, Pablo; Concha Nordemann, Miguel Luis Angel (Frontiers Media, 2021)
      The catecholaminergic system has received much attention based on its regulatory role in a wide range of brain functions and its relevance in aging and neurodegenerative diseases. In the present study, we analyzed the ...
    • Fuenzalida, Catalina; Dufeu Garfias, María Soledad; Poniachik Teller, Jaime Melchor; Roblero Cum, Juan Pablo; Valenzuela Pérez, Lucía Teresita; Beltrán Muñoz, Caroll Jenny (Frontiers Media, 2021)
      Alcoholic liver disease (ALD) is one of the leading causes of morbidity among adults with alcohol use disorder (AUD) worldwide. Its clinical course ranges from steatosis to alcoholic hepatitis, progressing to more severe ...
    • Negrin, Roberto; Duboy, Jaime; Íñiguez, Magaly; Reyes, Nicolás O.; Barahona Vásquez, Maximiliano; Ferrer, Gonzalo; Infante Calvo, Carlos Alberto; Jabes, Nicolás (Springernature, 2021)
      Background The use of unicompartmental knee arthroplasty (UKA) has increased and new technologies have been developed to improve patient survival and satisfaction, soft tissue balance, alignment, and component size. ...
    • Muñoz Quezada, María Teresa; Lucero, Boris; Castillo, Benjamín; Bradman, Asa; Zúñiga, Liliana; Baumert, Brittney O.; Iglesias Alamos, Veronica Paz; Muñoz, María Pía; Buralli, Rafael J.; Antini Irribarra, Carmen Andrea (Frontiers Media, 2021)
      Exposure to pesticides during infancy is associated with numerous adverse health outcomes. The assessment of knowledge and perception of pesticides exposure and risk among children has not been thoroughly studied. The aim ...
    • Pulgar, Eduardo; Schwayer, Cornelia; Guerrero, Néstor; López, Loreto; Márquez, Susana; Hartel, Steffen; Soto, Rodrigo; Heisenberg, Carl-Philipp; Concha Nordemann, Miguel Luis Angel (Elife Sciences Publications, 2021)
      The developmental strategies used by progenitor cells to allow a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here, we uncovered a mechanism of progenitor ...