Now showing items 901-920 of 11593

    • Durán, Javier; Nickel, Lennart; Estrada Hormazábal, Manuel Iván; Backs, Johannes; Van den Hoogenhof, Maarten M. G. (Frontiers Media, 2021)
      RNA splicing has been recognized in recent years as a pivotal player in heart development and disease. The Ca2C/calmodulin dependent protein kinase II delta (CaMKIId) is a multifunctional Ser/Thr kinase family and generates ...
    • Manterola Zúñiga, Marcia Carolina; Palominos, M. Fernanda; Calixto, Andrea (Frontiers Media, 2020)
      What defines whether the interaction between environment and organism creates a genetic memory able to be transferred to subsequent generations? Bacteria and the products of their metabolism are the most ubiquitous biotic ...
    • Marcelino, Ana Aline; Fregonezi, Guilherme; Marques, Layana; Lista Paz, Ana; Torres Castro, Rodrigo Hernán; Resqueti, Vanessa (Public Library Science, 2021)
      Background and purpose Sniff nasal inspiratory pressure (SNIP) is a voluntary inspiratory maneuver measured through a plug occluding one nostril. The investigation of the number of maneuvers necessary to reach the highest ...
    • Nieto Rojas, Rodrigo Antonio; Carrasco, Andrea; Corral Zavala, Sebastián Andrés; Castillo, Rolando; Gaspar Ramos, Pablo Arturo; Bustamante Calderón, María Leonor; Silva, Hernán (Frontiers Media, 2021)
      Brain Derived Neurotrophic Factor (BDNF) has been linked to cognitive symptoms of schizophrenia, which has been documented in previous reviews by several authors. However, a trend has recently emerged in this field moving ...
    • Saldías Maulén, María Paz; Maureira Fuentes, Diego Javier; Orellana Serradell, Octavio Andrés; Silva del Canto, Ian; Lavanderos Andrade, Boris Joan; Cruz, Pablo; Torres Paredes, Camila Esperanza; Cáceres Lluch, Mónica; Cerda Arancibia, Oscar Alejandro (MDPI, 2021)
      Breast cancer is one of the most frequent cancer types worldwide and the first cause of cancer-related deaths in women. Although significant therapeutic advances have been achieved with drugs such as tamoxifen and trastuzumab, ...
    • Pizarro Pennarolli, Catalina Paola; Sánchez Rojas, Carlos Felipe; Torres Castro, Rodrigo Hernán; Vera Uribe, Roberto Eugenio; Sánchez Ramírez, Diana C.; Vasconcello Castillo, Luis Eduardo; Solís Navarro, Lilian Verónica; Rivera Lillo, Gonzalo Bernardo (PEERJ, 2021)
      Background: Coronavirus disease has provoked much discussion since its first appearance. Despite it being widely studied all over the world, little is known about the impact of the disease on functional ability related ...
    • Sotomayor, Camilo G.; Oskooei, Sara Sokooti; Bustos, Nicolás; Nolte, Ilja M.; Gomes Neto, Antonio W.; Erazo, Marcia; Gormaz, Juan; Berger, Stefan P.; Navis, Gerjan J.; Rodrigo Salinas, Ramon; Dullaart, Robin P. F.; Bakker, Stephan J. L. (Elsevier, 2021)
      Background: Serum uric acid (SUA) is associated with fasting glucose in healthy subjects, and prospective epidemological studies have shown that elevated SUA is associated with increased risk of type 2 diabetes. Whether ...
    • Pérez de Arce Oñate, Edith; Quera, Rodrigo; Ribeiro Barros, Jaqueline; Sassaki, Ligia Yukie (Dove Medical, 2021)
      Inflammatory bowel disease (IBD) is a chronic condition that globally affects the health of people who suffer from it, deteriorating their quality of life (QoL). An aspect rarely explored by healthcare providers is the ...
    • Silva Astorga, Mariana Valentina; Mena Vergara, Luis Alejandro; Giacaman Sarah, Paula Loreto; Zapata, Solange (Elsevier, 2021)
      Objetivo: Reportar un caso de esporotricosis linfocutánea contraída en Chile y realizar una revisión de la literatura con énfasis en los hallazgos dermatoscópicos de las lesiones y en los casos reportados en el país. Caso ...
    • Villena, Fabián; Pérez, Jorge; Lagos, René; Dunstan Escudero, Jocelyn Mariel (BMC, 2021)
      Background: In Chile, a patient needing a specialty consultation or surgery has to frst be referred by a general practitioner, then placed on a waiting list. The Explicit Health Guarantees (GES in Spanish) ensures, by law, ...
    • Poblete Astroza, Daniela Lorena; Bernal, Fernando; Llull Morchio, Gabriel Eduardo; Archiles Olivares, Sebastián Gabriel; Vásquez, Patricia; Chanqueo Cornejo, Leonardo Andrés; Soto, Nicole; Lavanderos de Paz, María Angélica; Quiñones Sepúlveda, Luis Abel; Varela Figueroa, Nelson Miguel Edgardo (Frontiers Media, 2021)
      Background: Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor, and atazanavir (ATV), a protease inhibitor, are drugs widely used in antiretroviral therapy (ART) for people living with HIV. These drugs have ...
    • Lillo Moya, José Ignacio; Rojas Solé, Catalina Andrea; Muñoz Salamanca, Diego Ignacio; Panieri, Emiliano; Saso, Luciano; Rodrigo Salinas, Ramón (MDPI, 2021)
      Ischemic heart disease is a leading cause of death worldwide. Primarily, ischemia causes decreased oxygen supply, resulting in damage of the cardiac tissue. Naturally, reoxygenation has been recognized as the treatment of ...
    • Pérez Jeldres, Tamara; Álvarez Lobos, Manuel; Rivera Nieves, Jesús (Adis, 2021)
      Sphingosine-1-phosphate (S1P) is a bioactive lipid metabolite that exerts its actions by engaging 5 G-protein-coupled receptors (S1PR1-S1PR5). S1P receptors are involved in several cellular and physiological events, ...
    • Landaeta Aqueveque, Carlos; Ayala, Salvador; Poblete Toledo, Denis; Canals Lambarri, Mauricio María Guillermo (BMC, 2021)
      Trichinellosis is a foodborne disease caused by several Trichinella species around the world. In Chile, the domestic cycle was fairly well-studied in previous decades, but has been neglected in recent years. The aims of ...
    • Larraín, Catalina; Salinas, Marcia (Elsevier, 2021)
      La actividad deportiva en niños y adolescentes ha presentado un aumento sostenido en nuestro país en los últimos años; esto ha generado un aumento de las lesiones deportivas por sobreuso. Éstas pueden tener múltiples ...
    • González Stegmaier, R.; Cereceda, K.; Briones, J. L.; Beltrán Pavez, C.; Oyarzún Arrau, A.; Riquelme Barrios, S.; Selman, C.; Yarad, F.; Mahave, M.; Caglevic, C.; Morales, R.; Aguirre, A.; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo; Marsiglia, H.; Gazitúa, R.; Villarroel Espíndola, F. (Hindawi, 2021)
      COVID-19 is a pandemic caused by SARS-CoV-2. In Chile, half a million people have been infected and more than 16,000 have died from COVID-19. As part of the clinical trial NCT04384588, we quantified IgG against S1-RBD of ...
    • Baar, Alejandro (Elsevier, 2021)
      Las deformidades torsionales de las extremidades inferiores corresponden a una de las causas de visita más frecuente al ortopedista infantil. En la mayoría de los casos, estas consultas son innecesarias, pues se trata de ...
    • Mura Castro, Jorge Marcelo (Georg Thieme Verlag KG, Germany, 2021)
    • Zúñiga Contreras, Marcela Alejandra; Hauck, Isabel Noemí; Valenzuela Cortés, Romina; Barraza Olivares, Marlon; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectología, 2021)
      Toxoplasma gondii es un protozoo que afecta a un tercio de la población mundial y cuya seroprevalencia actualizada en niños con cáncer en nuestro medio, se desconoce. Objetivo: Describir la seroprevalencia de IgG anti-T. ...
    • Gaete Argel, Aracelly Janis; Velásquez, Felipe; Márquez Badilla, Chantal Loretto; Rojas Araya, Bárbara; Bueno Nieto, Constanza Francisca; Marín Rojas, Josefina; Cuevas Zúñiga, Miguel; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Frontiers Media, 2021)
      Tellurium oxyanion, tellurite (TeO3-2), is a highly toxic compound for many organisms. Its presence in the environment has increased over the past years due to industrial manufacturing processes and has been associated ...