Browsing by Subject "Periodontitis"

Now showing items 21-37 of 37

    • Humanized mouse models for the study of periodontitis: An opportunity to elucidate unresolved aspects of ... 
      Rojas, Carolina; García, Michelle P.; Polanco, Alan F.; González Osuna, Luis; Sierra Cristancho, Alfredo José; Melgar Rodríguez, Samanta Azucena; Cafferata Chea, Emilio Alfredo; Vernal Astudillo, Rolando Marcelo (Frontiers Media, 2021)
      Periodontitis is an oral inflammatory disease in which the polymicrobial synergy and dysbiosis of the subgingival microbiota trigger a deregulated host immune response, that leads to the breakdown of tooth-supporting ...
    • Increased levels of the T-helper 22-associated cytokine (interleukin-22) and transcription factor (aryl ... 
      Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Rojas, L.; Alvarez, C.; Monasterio, G.; Carvajal Pavez, Paola; Vernal Astudillo, Rolando (Wiley, 2017)
      Background and ObjectiveTwo new T-helper (Th) phenotypes have been recently described and named Th9 and Th22 lymphocytes; however, their role in the pathogenesis of periodontitis remains unclear. This study was aimed to ...
    • Interleukin-35 inhibits alveolar bone resorption by modulating the Th17/Treg imbalance during periodontitis 
      Cafferata, Emilio; Terraza Aguirre, Claudia; Barrera, Romina; Faúndez, Nicolás; González, Nicolás; Rojas, Carolina; Melgar Rodríguez, Samanta; Hernández, Marcela; Carvajal, Paola; Cortez, Cristian; González, Fermín; Covarrubias, Cristian; Vernal Astudillo, Rolando (Wiley, 2020)
      Aim T lymphocytes play a central role during the pathogenesis of periodontitis, and the imbalance between the pathogenic T-helper type 17 (Th17) and protective T-regulatory (Treg) lymphocytes determines the tooth-supporting ...
    • Longitudinal analysis of metalloproteinases, tissue inhibitors of metalloproteinases and clinical parameters ... 
      Pozo, P.; Valenzuela, M.; Melej, C.; Zaldívar, M.; Puente, J.; Martínez, B.; Gamonal Aravena, Jorge Antonio (2005)
      Background: The aim of this work was to improve the assessment of the periodontal disease status through measurements of extracellular matrix metalloproteinases (MMPs) and their tissular inhibitors (TIMPs) in the ...
    • MMP-8, TRAP-5, and OPG levels in GCF diagnostic potential to discriminate between healthy patients’, mild ... 
      Hernández, Marcela; Baeza Paredes, Mauricio; Contreras Balbontín, Johanna; Sorsa, Timo; Tervahartiala, Taina; Valdés Salgado, Macarena; Chaparro, Alejandra; Hernández Ríos, Patricia (MDPI, 2020)
      Biomarkers represent promising aids in periodontitis, host-mediate diseases of the tooth-supporting tissues. We assessed the diagnostic potential of matrix metalloproteinase-8 (MMP-8), tartrate-resistant acid phosphatase-5 ...
    • Molecular signatures of extracellular vesicles in oral fluids of periodontitis patients 
      Chaparro Padilla, Alejandra; Weber Aracena, Laura; Realini Fuentes, Ornella; Albers Busquetts, Daniela; Hernández Ríos, Marcela; Ramírez Lobos, Valeria; La Rocca, Andrés Pascual; Nart Molina, José; Beltrán Varas, Víctor; Acuña Gallardo, Stephanie; Sanz Ruiz, Antonio (Wiley, 2020)
      Objective To characterize extracellular vesicles (EVs) in gingival crevicular fluid (GCF) and saliva samples from healthy/gingivitis and periodontitis patients and correlate them with clinical inflammatory periodontal ...
    • Niveles de piridinolina (ICTP) en el fluido gingival crevicular (FGC) en la periodontitis crónica 
      González Quesada, Jorge; Rivera Álvarez, Sonia (Universidad de Costa Rica, Facultad de Odontología, 2016)
      Pyridinoline (ICTP) is a molecule of collagen degradation that after bone resorption and degradation of the collagen matrix is released into the circulation and can not pass anabolic pathways and reused during collagen ...
    • O-polysaccharide plays a major role on the virulence and immunostimulatory potential of aggregatibacter ... 
      Monasterio, Gustavo; Ormeño Castillo, Francisca; Astorga, Jéssica; Hoare Teuche, Anilei; Terraza, Claudia; Cafferata, Emilio A.; Villablanca, Eduardo J.; Vernal Astudillo, Rolando Marcelo (Frontiers Media, 2020)
      Aggregatibacter actinomycetemcomitans is a Gram-negative oral bacterium with high immunostimulatory and pathogenic potential involved in the onset and progression of periodontitis, a chronic disease characterized by aberrant ...
    • Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-κ B ligand, ... 
      Dutzan Muñoz, Nicolás; Gamonal Aravena, Jorge Antonio; Silva, Augusto; Sanz, Mariano; Vernal Astudillo, Rolando (2009)
      Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor activator of nuclear factor-κ B ligand (RANKL). The aim of this ...
    • Periodontal disease and its impact on general health in Latin America. Section II: Introduction part II 
      Carvajal, Paola; Vernal Astudillo, Rolando; Reinero, Daniela; Malheiros, Zilson; Stewart, Bernal; Pannuti, Claudio Mendes; Romito, Giuseppe Alexandre (Sociedade Brasileira de Pesquisa Odontologica, 2020)
      The epidemiological data on gingivitis and periodontitis in Latin America are scarce, as the majority of the Latin American studies have analyzed probing depth instead of clinical attachment loss. Reported data have shown ...
    • Periodontal disease and its impact on general health in Latin America: LAOHA Consensus Meeting Report 
      Romito, Giuseppe; Feres, Magda; Gamonal Aravena, Jorge; Gómez, Mariel; Carvajal, Paola; Pannuti, Claudio; Duque Duque, Andrés; Romanelli, Hugo; Rosing, Cassiano Kuchenbecker; Aranguiz Freyhofer, Vicente; Cavagni, Juliano; Fischer, Ricardo Guimaraes; Figueiredo, Luciene; Campos de Almeida Carrer, Fernanda; Malheiros, Zilson; Stewart, Bernal; Sanz, Mariano; Ryan, María (Sociedade Brasileira de Pesquisa Odontologica, 2020)
      Periodontal diseases are considered a worldwide public health problem, owing to their high prevalence in developed and developing countries. Periodontitis may lead to tooth loss, which can impact oral health-related quality ...
    • Periodontitis and alzheimer's disease 
      Sansores España, Daniel; Carrillo Ávila, Arelly; Melgar Rodríguez, Samanta Azucena; Díaz Zúñiga, Jaime; Martínez Aguilar, Víctor (Medicina Oral, España, 2021)
      Background: Alzheimer's disease (AD), the main cause of dementia in the adult population, is characterized by a progressive loss of cognitive function. It is considered that neuroinflammation plays a fundamental role in ...
    • Periodontitis and gestational diabetes mellitus: a potential inflammatory vicious cycle 
      Bendek, María José; Canedo Marroquín, Gisela; Realini, Ornella; Retamal, Ignacio N.; Hernández Ríos, Emma; Hoare Teuche, Anilei Paz; Busso, Dolores; Monteiro, Lara J.; Illanes, Sebastián E.; Chaparro, Alejandra (MDPI, 2021)
      Periodontitis is a chronic inflammatory immune disease associated with a dysbiotic state, influenced by keystone bacterial species responsible for disrupting the periodontal tissue homeostasis. Furthermore, the severity ...
    • Senescent CD4+CD28− T lymphocytes as a potential driver of Th17/Treg imbalance and alveolar bone resorption ... 
      González Oosuna, Luis Gustavo; Sierra Cristancho, Alfredo José; Cafferata Chea, Emilio Alfredo; Melgar Rodríguez, Samanta Azucena; Rojas Pérez, Carolina Isabel; Carvajal Pavez, Paola Lorena; Cortez, Cristian; Vernal Astudillo, Rolando Marcelo (MDPI, 2022)
      Senescent cells express a senescence-associated secretory phenotype (SASP) with a pro-inflammatory bias, which contributes to the chronicity of inflammation. During chronic inflammatory diseases, infiltrating CD4(+) T ...
    • Subgingival microbiota of chronic periodontitis subjects from different geographic locations 
      Haffajee, A.; Bogren, A.; Hasturk, H.; Feres, M.; López, N.; Socransky, S. (2004)
      BACKGROUND: Most clinical studies assume that the subgingival microbiota is similar from one geographic location to another. The purpose of the present investigation was to examine the composition of the subgingival ...
    • The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation 
      Abusleme, Loreto; Dupuy, Amanda; Dutzan, Nicolás; Silva, Nora; Burleson, Joseph; Strausbaugh, Linda; Gamonal Aravena, Jorge; Diaz, Patricia (2013)
      The goals of this study were to better understand the ecology of oral subgingival communities in health and periodontitis and elucidate the relationship between inflammation and the subgingival microbiome. Accordingly, we ...
    • Vascular endothelial growth factor: A translational view in oral non-communicable diseases 
      Niklander, Sven; Bordagaray San Martín, María José; Fernández, Alejandra; Hernández Ríos, Emma Marcela (MDPI, 2021)
      Vascular endothelial growth factors (VEGFs) are vital regulators of angiogenesis that are expressed in response to soluble mediators, such as cytokines and growth factors. Their physiologic functions include blood vessel ...