Now showing items 571-590 of 898

    • Peña Oyarzún, Daniel; Batista González, Ana; Kretschmar, Catalina; Burgos, Paulina; Lavandero González, Sergio; Morselli, Eugenia; Criollo Céspedes, Alfredo (Elsevier, 2020)
      Polycystin-2 (PC2) is a calcium channel that can be found in the endoplasmic reticulum, the plasmatic membrane, and the primary cilium. The structure of PC2 is characterized by a highly ordered C-terminal tail with an ...
    • Batista González, Ana; Vidal Álvarez, Roberto; Criollo Céspedes, Alfredo; Carreño Márquez, Leandro (Frontiers Media, 2020)
      Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...
    • Bascones, Antonio; Gamonal Aravena, Jorge Antonio; Gómez Carranza, María Leyla; Silva, Augusto; González, Miguel Ángel (Quintessence Publishing, 2004-10)
      The aim of this study was to evaluate the relationship between the accumulation of interleukins IL-1beta, TNF-alpha, IL-8, and chemokine RANTES (Regulated upon Activation Normal T-cell Expressed and Secreted) in gingival ...
    • Fariña Sirandoni, Rodrigo; Hinojosa, Andrés; Sánchez, Martín; Olate, Sergio (Lippicott Williams & Wilkins, 2015)
      There are 2 types of distraction devices for mandibular distraction: buried and external. The advantage of buried devices is the stability, but the difficulty in removing the screws is the greatest disadvantage. To resolve ...
    • Lin, T. H.; Pajarinen, J.; Lu, L.; Nabeshima, A.; Córdova Jara, Luis; Yao, Z.; Goodman, S. B. (Elsevier, 2017)
      Inflammation is a defensive mechanism for pathogen clearance and maintaining tissue homeostasis. In the skeletal system, inflammation is closely associated with many bone disorders including fractures, nonunions, periprosthetic ...
    • Lin, Tzu-hua; Pajarinen, Jukka; Sato, Taishi; Loi, Florence; Fan, Changchun; Córdova Jara, Luis; Nabeshima, Akira; Gibon, Emmanuel; Zhang, Ruth; Yao, Zhenyu; Goodman, Stuart (Elsevier, 2016)
      Total joint replacement is a cost-effective surgical procedure for patients with end-stage arthritis. Wear particle-induced chronic inflammation is associated with the development of periprosthetic osteolysis. Modulation ...
    • González Quesada, Jorge; Rivera Álvarez, Sonia (Universidad de Costa Rica, Facultad de Odontología, 2016)
      Pyridinoline (ICTP) is a molecule of collagen degradation that after bone resorption and degradation of the collagen matrix is released into the circulation and can not pass anabolic pathways and reused during collagen ...
    • Goulart, D. R.; Muñoz, P.; Olate, S.; Moraes, M. de; Fariña Sirandoni, Rodrigo (Churchill Livingstone, 2015)
      The aim of this research was to compare the condylar morphology of patients with unilateral condylar hyperplasia (UCH) and patients with a class III skeletal relationship using cone beam computed tomography (CBCT). A ...
    • Suazo, Yerko; Rada, Gabriel (NLM (Medline), 2018)
      INTRODUCTION: Subarachnoid hemorrhage is a neurosurgical emergency that requires timely diagnosis due to its severity and the existence of therapeutic measures that are effective when carried out in time. The most used ...
    • Ortega Pinto, Ana; Fariña Espinoza, Valeska Gissel; Espinoza Santander, Iris; Gallardo Neira, Andrés Alberto; Acosta Christian, Sergio Alejandro (Wiley, 2007-05)
      Aim  To determine the frequency with which the histopathological diagnosis of periapical lesions contributes to a change in the clinical diagnosis. Methodology  Cases having a clinical diagnosis of disease resulting ...
    • Ortega Pinto, Ana; Fariña, V.; Gallardo, A.; Espinoza Santander, Iris; Acosta, S. (2007)
      Aim To determine the frequency with which the histopathological diagnosis of periapical lesions contributes to a change in the clinical diagnosis. Methodology Cases having a clinical diagnosis of disease resulting from ...
    • Cáceres Rojas, Gabriela; Salamanca, Carlos; Krause, Bernardo J.; Recabarren, Andrea S.; Recabarren, Pamela; Pantoja Parada, Pedro; Leiva Villagra, Noemi; Pardo Vargas, Rosa; Santos, José Luis; Suazo Sanhueza, José Lorenzo (Future Medicine, 2020)
      Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker of global DNA methylation, and the effect of MTHFR functional variants on this variable. Patients & methods: ...
    • Rodíguez, Fernando A.; Gana, María José; Yubero, María Joao; Zillmann Geerdts, Gisela del Carmen; Krämer Strenger, Susanne; Catalán, Javiera; Rubio Astudillo, Julia; González, Sergio; Liu, Lu; Ozoemena, Linda; Mellerio, Jemima M.; McGrath, John A.; Palisson, Francis; Conget, Paulette (Elsevier, 2012-02)
    • Jara Sandoval, José Antonio; Rojas Rivera, Diego; Castro Castillo, Vicente; Fuentes Retamal, Sebastián; Sandoval Acuña, Cristian; Parra, Eduardo; Pavani, Mario; Maya Arango, Juan Diego; Ferreira Parker, Jorge; Catalán Díaz, Mabel (Elsevier, 2020)
      Introduction: Colorectal cancer (CRC) is a critical health issue worldwide. The high rate of liver and lung metastasis associated with CRC creates a significant barrier to effective and efficient therapy. Tumour cells, ...
    • Urzúa Orellana, Blanca; Martínez, Blanca; Ortega Pinto, Ana; Adorno Farías, Daniela; Morales Bozo, Irene; Riadi, Gonzalo; Jara, Lilian; Plaza, Anita; Lefimil, Claudia; Lozano, Carla; Reyes, Monserrat (Elsevier, 2015)
      Objective: Amelogenesis imperfecta (AI) is a group of clinically and genetically heterogeneous inherited conditions, causing alterations in the structure of enamel and chemical composition of enamel matrix during development. ...
    • Smalley, Susan; Preiss, Yudith; Suazo Sanhueza, José Lorenzo; Vega, Javier; Angellotti, Isidora; Lagos, Carlos; Rivera, Enzo; Kleinsteuber, Karin; Campion, Javier; Martínez, J. Alfredo; Maiz, Alberto; Santos, José Luis (Sociedade Brasileira de Genética, 2015)
      Cerebrotendinous Xanthomatosis (CTX), a rare lipid storage disorder, is caused by recessive loss-of-function mutations of the 27-sterol hydroxylase (CYP27A1), producing an alteration of the synthesis of bile acids, with ...
    • Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; Silva, Patricio; Venegas, Sebastián; Criollo Céspedes, Alfredo; Torres Gómez, Vicente (Wiley, 2020)
      Potentially malignant lesions, commonly referred to as dysplasia, are associated with malignant transformation by mechanisms that remain unclear. We recently reported that increased Wnt secretion promotes the nuclear ...
    • Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; Maturana Ramírez, Andrea; Torres Gómez, Vicente (Elsevier, 2019)
      Objectives: To evaluate the localization of β-catenin in oral dysplastic cells, the expression of target genes upregulated in oral dysplasia, and the role of Wnt ligands in these events. Materials and methods: Subcellular ...
    • Pintor Willcock, María Fernanda; Campos Salvaterra, O. (2007)
      Los implantes cigomáticos están indicados en casos de reabsorciones maxilares severas. Esto permitiría eliminar la necesidad de injertos óseos o levantamientos de seno de manera de recuperar el volumen óseo necesario para ...
    • Villanueva Maffei, Julio; Wallach, Daniel; Pantoja Parada, Pedro; Hampel, Hans; Marino, Antonio (Sociedad Odontológica de Chile, 1998-11)
      La endocarditis infecciosa es una infección microbiana de la superficie endocárdica, que involucra frecuentemente las válvulas cardíacas. El patógeno más frecuente es el Streptococus viridans, miembro importante de la flora ...