Now showing items 534-553 of 898

    • González Bergas, Fermín; Ortiz, Carolina; Reyes Rojas, Montserrat; Dutzan Muñoz, Nicolás; Patel, Vyomesh; Pereda, Cristián; Gleisner Muñoz, María Alejandra; López Nitsche, Mercedes; Gutkind, J. Silvio; Salazar Onfray, Flavio (John Wiley & Sons Ltd,, 2014)
      We have previously reported a novel method for the production of tumour-antigen-presenting cells (referred to as TAPCells) that are currently being used in cancer therapy, using an allogeneic melanomaderived cell lysate ...
    • Lopez, N.; Lobos, N. (1976)
      A case of metastatic neoplasm developing in the gingiva from a primary lesion, probably sited in the gastric mucosa, has been reported. In this case, the first demonstrable metastatic lesion was located in the gingiva. The ...
    • Jara, J. A.; López Muñoz, R. (Elsevier, 2015)
      For decades, metformin has been the first-line drug for the treatment of type II diabetes mellitus, and it thus is the most widely prescribed antihyperglycemic drug. Retrospective studies associate the use of metformin ...
    • Wu, Darong; Akl, Elie A.; Guyatt, Gordon H.; Devereaux, Philip J.; Brignardello Petersen, Romina; Prediger, Barbara; Patel, Krupesh; Patel, Namrata; Lu, Taoying; Zhang, Yuan; Falavigna, Maicon; Santesso, Nancy; Mustafa, Reem A.; Zhou, Qi; Briel, Matthias; Schünemann, Holger J. (BioMed Central Ltd., 2014)
      Background: Although even randomization (that is, approximately 1:1 randomization ratio in study arms) provides the greatest statistical power, designed uneven randomization (DUR), (for example, 1:2 or 1:3) is used to ...
    • Sierra Cristancho, Alfredo José; González Osuna, Luis; Poblete, Daniela; Cafferata Chea, Emilio Alfredo; Carvajal Pavez, Paola Lorena; Lozano Moraga, Carla Paola; Vernal Astudillo, Rolando Marcelo (Nature, 2021)
      This study aimed to analyze the root anatomy and root canal system morphology of mandibular first premolars in a Chilean population. 186 teeth were scanned using micro-computed tomography and reconstructed three-dimensionally. ...
    • Venegas Hermosilla, Juan; Díaz Cuevas, Laín; Rojas, Tamara; Miranda, Sandra; Jercic, M. I.; González, Christian; Coñoepán, William; Vargas, Álex; Pichuantes, Sergio; Gajardo Ramírez, Marta Kelly; Rodríguez Borges, Jorge; Sánchez, Gittith (Stefan´ski Institute of Parasitology, 2013)
      The objective of this study was to investigate if there is specific host-parasite association in Chilean populations of Trypanosoma cruzi. For this purpose, two groups of parasites were analyzed, one from chronic chagasic ...
    • Martin, J.; Fernandez, E.; Estay, J.; Gordan, V.; Mjor, I.; Moncada, G. (2013)
      Replacement of dental restorations has been the traditional treatment for restorations that are defective. In this five-year randomized clinical trial, restorations with localized marginal defects were treated with ...
    • Johnston, Bradley C.; Ebrahim, Shanil; Carrasco Labra, Alonso; Furukawa, Toshi A.; Patrick, Donald L.; Crawford, Mark W.; Hemmelgarn, Brenda R.; Schunemann, Holger J.; Guyatt, Gordon H.; Nesrallah, Gihad (BMJ Publishing Group, 2015)
      Introduction Patient-reported outcomes (PROs) are often the outcomes of greatest importance to patients. The minimally important difference (MID) provides a measure of the smallest change in the PRO that patients perceive ...
    • Strauss Avendaño, Franz; Stahli, Alexandra; Kobatake, Reiko; Tangl, Stefan; Heimel, Patrick; Alccayhuaman, Karol Ali Apaza; Schosserer, Markus; Hackl, Matthias; Grillari, Johannes; Gruber, Reinhard (Wiley, 2020)
      Objectives MicroRNAs (miRNAs) are small noncoding RNAs demonstrated as critical post-transcriptional modulators in dental tissues and bone regeneration, particularly miR-21-5p. However, the role of miR-21-5p in the healing ...
    • Sorsa, Timo; Mäntylä, Päivi; Tervahartiala, Taina; Pussinen, Pirkko J.; Gamonal Aravena, Jorge Antonio; Hernández Ríos, Emma (John Wiley & Sons A/S, 2011-09)
    • Hernández Ríos, Emma; Martínez, Benjamín; Tejerina, José María; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (2007)
      Matrix metalloproteinase (MMP)-13 is a collagenase involved in extracellular matrix degradation either by its direct degradative effects or by processing bioactive substrates. The aim of this study was to determine the ...
    • Hernández, Marcela; Baeza Paredes, Mauricio; Contreras Balbontín, Johanna; Sorsa, Timo; Tervahartiala, Taina; Valdés Salgado, Macarena; Chaparro, Alejandra; Hernández Ríos, Patricia (MDPI, 2020)
      Biomarkers represent promising aids in periodontitis, host-mediate diseases of the tooth-supporting tissues. We assessed the diagnostic potential of matrix metalloproteinase-8 (MMP-8), tartrate-resistant acid phosphatase-5 ...
    • Fernández, Javier; Jiménez, Constanza; Benadof, Dafna; Morales, Paulina; Astorga, Jéssica; Cáceres, Felipe; Hernández Ríos, Emma Marcela; Fernández, Alejandra; Valenzuela, Fernando (MDPI, 2022)
      Rosacea is a chronic inflammatory skin disease whose prevalence rates remain unknown in Chile. Laboratory benchmark testing for this disease is not useful, therefore, we aimed to evaluate the gingival crevicular fluid (GCF) ...
    • Favaro Trombone, Ana Paula; Cavalla Ruiz, Ian Franco; Varize Silveira, Elcia María; Andreo, Camile Bermejo; Francisconi, Carolina Favaro; Fonseca, Angélica Cristina; Letra, Ariadne; Silva, Renato Menezes; Garlet, Gustavo Pompermaier (2016)
      Increased matrix metalloproteinases (MMPs) activity is a hallmark of periapical granulomas. However, the factors underlying the MMPs expression modulation in healthy and diseased periapical tissues remains to be determined. ...
    • Stuardo Avila, Valeria Andrea; Manríquez Urbina, José Manuel; Fajreldin Chuaqui, Valentina Eliana; Belmar Prieto, Julieta; Valenzuela Santibáñez, Victoria (2016)
      In Chile, over 14,000 adults are living with HIV receive antiretroviral therapy (HAART). Adequate adherence to HAART has a major impact on survival. There is little consensus on the causes of poor adherence, due to the ...
    • Hevia, J.; Fresno Rivas, María Consuelo; Martín Casielles, Javier; Moncada, G.; Letelier, C.; Oliveira, Osmir Batista; Fernández Godoy, Eduardo (Sociedad de Periodoncia de Chile, 2013)
      terceros molares sanos, con indicación de exodoncia, de donantes sanos de edades entre 15 y 30 años fueron obtenidos mediante consentimiento informado. Luego de limpiarlos, desinfectarlos, incluirlos en resina epóxica y ...
    • Fariña, Rodrigo; Valladares, Salvador; Raposo Castillo, Araceli; Silva, Francisco (Elsevier, 2018)
      Purpose: There are multiple conditions that may affect the development of the middle third of the face and with varying degrees of severity. The surgical treatment alternatives for major midfacial sagittal deficiencies ...
    • García-Salum, Tamara; Villablanca, Andrea; Matthäus, Franziska; Tittarelli, Andrés; Baeza, Mauricio; Pereda, Cristián; Gleisner Muñoz, María Alejandra; González, Fermín; López, Mercedes; Hoheisel, Jörg; Norgauer, Johannes; Gebicke Haerter, Peter; Salazar Onfray, Flavio (Impact Journals LLC, 2018)
      Purpose: We previously showed that autologous dendritic cells (DCs) loaded with an allogeneic heat shock (HS)-conditioned melanoma cell-derived lysate, called TRIMEL, induce T-cell-mediated immune responses in stage IV ...
    • Chaparro Padilla, Alejandra; Weber Aracena, Laura; Realini Fuentes, Ornella; Albers Busquetts, Daniela; Hernández Ríos, Marcela; Ramírez Lobos, Valeria; La Rocca, Andrés Pascual; Nart Molina, José; Beltrán Varas, Víctor; Acuña Gallardo, Stephanie; Sanz Ruiz, Antonio (Wiley, 2020)
      Objective To characterize extracellular vesicles (EVs) in gingival crevicular fluid (GCF) and saliva samples from healthy/gingivitis and periodontitis patients and correlate them with clinical inflammatory periodontal ...
    • Dezerega Piwonka, Andrea; Osorio Alfaro, Constanza; Mardones Peñailillo, Jeannette Isabel; Mundi, V.; Dutzan Muñoz, Nicolás; Franco Martínez, María Eugenia; Gamonal Aravena, Jorge Antonio; Oyarzún Droguett, Alejandro; Overall, M. C.; Hernández Ríos, Emma (John Wiley & Sons, 2010-10)
      Aim  To study the expression of monocyte chemotactic protein-3 (MCP-3, also known as chemokine CCL-7) in tissue from apical lesions (AL) and to associate MCP-3 expression with symptomatic or asymptomatic apical ...