Browsing by Author "Escobar, Alejandro"

Now showing items 1-5 of 5

    • ATP Induces IL-1 β Secretion in Neisseria gonorrhoeae-Infected Human Macrophages by a Mechanism Not Related ... 
      Garciá, Killen; Escobar, Gisselle; Mendoza, Pablo; Beltran, Caroll; Pérez, Claudio; Arancibia, Sergio; Vernal Astudillo, Rolando; Rodas, Paula; Acunã-Castillo, Claudio; Escobar, Alejandro (Hindawi Limited, 2016)
      Neisseria gonorrhoeae (Ngo) has developed multiple immune evasion mechanisms involving the innate and adaptive immune responses. Recent findings have reported that Ngo reduces the IL-1𝛽 secretion of infected human ...
    • In vivo antitumor effect against murine cells of CT26 colon cancer and EL4 lymphoma by autologous whole ... 
      Barrera Ávalos, Carlos Esteban; Díaz, Ximena; Madrid, Sebastián; Michelson, Sofía A.; Robles Planells, Claudia Julieta; Sánchez Guerrero, Giselle; Ahumada, Viviana; Mella Torres, Andrea Jesús; Rojo, Leonel E.; Imarai Bahamonde, Mónica; Milla, Luis A.; Leiva Salcedo, Elías; Murgas, Paola; Fernández, Ricardo; Escobar, Alejandro; Acuña Castillo, Claudio (Hindawi, 2021)
      Active immunotherapy against cancer is based on immune system stimulation, triggering efficient and long-lasting antigen-specific immune responses. Immunization strategies using whole dead cells from tumor tissue, containing ...
    • Lipopolysaccharide inhibits the channel activity of the P2X7 receptor 
      Leiva Salcedo, Elías; Coddou, Claudio; Rodríguez, Felipe; Penna, Antonello; López, Ximena; Neira, Tanya; Fernández, Ricardo; Imarai, Mónica; Rios, Miguel; Escobar, Jorge; Montoya, Margarita; Huidobro Toro, Juan; Escobar, Alejandro; Acuña Castillo, Claudio (2011)
      The purinergic P2X7 receptor (P2X7R) plays an important role during the immune response, participating in several events such as cytokine release, apoptosis, and necrosis. The bacterial endotoxin lipopolysaccharide (LPS) ...
    • Neisseria gonorrhoeae Modulates Immunity by Polarizing Human Macrophages to a M2 Profile 
      Ortiz, María Carolina; Lefimil Puente, Claudia; Rodas, Paula I.; Vernal Astudillo, Rolando; López, Mercedes; Acuña Castillo, Claudio; Imarai, Mónica; Escobar, Alejandro (Public Library Science, 2015)
      Current data suggest that Neisseria gonorrhoeae is able to suppress the protective immune response at different levels, such as B and T lymphocytes and antigen-presenting cells. The present report is focused on gonococcus ...
    • α-2-macroglobulin in saliva is associated with glycemic control in patients with type 2 diabetes mellitus 
      Aitken, Juan; Ortiz, Carolina; Morales Bozo, Irene; Rojas Alcayaga, Gonzalo; Baeza, Mauricio; Beltran, Caroll; Escobar, Alejandro (Hindawi Limited, 2015)
      © 2015 Juan Pablo Aitken et al.Background. Subjects with type 2 diabetes mellitus (DM2) require an adequate glycemic control to avoid diabetic complications. Currently, saliva biomarkers are used as a diagnostic tool and ...