Browsing by Subject "Destruction complex"

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    • Expression profile of components of the beta-catenin destruction complex in oral dysplasia and oral cancer 
      Goñi, Francisca J.; Peña Oyarzún, Daniel Alejandro; Torres Gómez, Vicente A.; Reyes, Montserrat (Medicina Oral, 2021)
      Background: Oral cancer represents the sixth most common cancer in the world and is associated with 40-50% survival at 5 years. Within oral malignancies, oral squamous cell carcinoma (OSCC) is commonly preceded by potentially ...
    • Wnt/beta-Catenin Signaling in Oral Carcinogenesis 
      Reyes Rojas, Montserrat; Flores Lillo, Tania; Betancur, Diego; Peña Oyarzún, Daniel; Torres Gómez, Vicente (MDPI, 2020)
      Oral carcinogenesis is a complex and multifactorial process that involves cumulative genetic and molecular alterations, leading to uncontrolled cell proliferation, impaired DNA repair and defective cell death. At the ...