Now showing items 161-180 of 898

    • Lillo Urzúa, Paloma; Núñez Murillo, Olinda; Castro Sepúlveda, Mauricio; Torres Quintana, María Angélica; Lladser Caldera, Álvaro; Quest, Andrew F. G.; Espinoza Robles, Carolina; Llanos Vidal, Paola; Wehinger, Sergio (MDPI, 2020)
      Elevated free fatty acids (FFAs) impair beta cell function and reduce beta cell mass as a consequence of the lipotoxicity that occurs in type 2 diabetes (T2D). We previously reported that the membrane protein caveolin-1 ...
    • Véliz Méndez, Sebastián; Huber, Hinrich; Yubero, Maria Joao; Fuentes, Ignacia; Alsayer, Fatimah; Kramer, Susanne M. (Wiley, 2020)
      Objectives: To present early teeth extractions as a treatment option in severe dental crowding in patients with generalized recessive dystrophic epidermolysis bullosa (RDEB). Materials and methods: Three patients with ...
    • Cavalla Ruiz, Franco; Letra, A.; Silva, R. M.; Garlet, G. P. (SAGE, 2020)
      Periodontal and periapical lesions are infectious inflammatory osteolitytic conditions in which a complex inflammatory immune response mediates bone destruction. However, the uncertainty of a lesion's progressive or stable ...
    • Magrin, Gabriel Leonardo; Strauss Avendaño, Franz; Magalhães Benfatti, César Augusto; Cople Maia, Lucianne; Gruber, Reinhard (MDPI, 2020)
      Short-chain fatty acids (SCFA), bacterial metabolites released from dental biofilm, are supposed to target the oral epithelium. There is, however, no consensus on how SCFA affect the oral epithelial cells. The objective ...
    • Bachelet, Vivienne C.; Carrasco, Víctor A.; Bravo Córdova, Fabiana; Díaz, Rubén A.; Lizana, Francisca J.; Meza Ducaud, Nicolás; Pardo Hernández, Héctor; Uribe, Francisco A.; Vergara, Alonso F.; Villanueva Maffei, Julio; Navarrete, María S. (BMJ, 2020)
      Introduction Quality of reporting refers to how published articles communicate how the research was done and what was found. Gaps and imprecisions of reporting hamper the assessment of the methodological quality and internal ...
    • Lee, Jung-Seok; Jeon, Yoon-Sun; Strauss Avendaño, Franz; Jung, Hoi-In; Gruber, Reinhard (Nature, 2020)
      This study aimed to compare the accuracy and reliability of digital versus conventional clinical measurements of the width of keratinized tissue. To this end, the keratinized tissue width was measured at 110 tooth sites ...
    • Dávila-Sánchez, Andrés; Gutiérrez Reyes, Mario; Bermúdez, Jorge Pailover; Méndez Bauer, María Lujan; Hilgemberg, Bruna; Sauro, Salvatore; Loguercio, Alessandro D.; Galvao Arrais, César Augusto (Elsevier, 2020)
      Objectives. To evaluate the effect of experimental dentin pre-treatment solutions formulated with different flavonoids on microtensile bond strength (mu TBS), nanohardness (NH) and ultra-morphological characteristics of ...
    • Medeiros Maran, Bianca; Larocca de Geus, Juliana; Gutiérrez Reyes, Mario; Heintze, Siegward; Tardem, Chane; Barceleiro, Marcos O.; Reis, Alessandra; Loguercio, Alessandro D. (Elsevier, 2020)
      Objective: A systematic review and a meta-analysis were performed to answer the following research question: Are there differences in the color match and surface texture of nanofilled/nanohybrid and hybrid composite ...
    • Robles Planells, Claudia; Barrera Ávalos, Carlos; Rojo, Leonel E.; Spencer, Eugenio; Cortez San Martín, Eugenio; Matiacevich, Silvia; Pavez, Jorge; Milla, Luis A.; Navarro, Franco D.; Martínez, Brandon A; Bravo, Francisco J.; Mella, Andrea; Huidobro Toro, Juan Pablo; Fernández, Ricardo; Escobar Álvarez, Alejandro; Acuña Castillo, Claudio (Hindawi, 2020)
      Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of specific antitumor immune ...
    • Cafferatta Chea, Emilio; Castro Saavedra, Sebastián; Fuentes Barros, Gonzalo; Melgar Rodríguez, Samanta; Rivera Rodríguez, Felipe; Carvajal Pavez, Paola; Hernández Ríos, Emma; Cortés, Bastián; Cortez, Cristian; Cassels Niven, Bruce; Vernal Astudillo, Rolando (Wiley, 2020)
      Background During periodontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappa B ligand (RANKL), which is ...
    • Órdenes Aenishanslins, Nicolás; Anziani Ostuni, Giovanni; Monrás, Juan Pablo; Tello, Alejandra; Bravo Rodríguez, Denisse; Toro Ascuy, Daniela; Soto Rifo, Ricardo; Prasad, Paras N.; Pérez Donoso, José (MDPI, 2020)
      In this study, we introduce a biological method for the production of ternary Quantum Dots (QDs): complex nanostructures with tunable optical and structural properties that utilizes post-synthesis modifications through ...
    • Strauss Avendaño, Franz Josef; Kuchler, Ulrike; Kobatake, Reiko; Heimel, Patrick; Tangl, Stefan; Gruber, Reinhard (Wiley, 2020)
      Acid bone lysates (ABLs) represent the growth factors and other molecules released during autologous graft resorption. However, the impact of these bone-derived growth factors on the healing of bone defects has not yet ...
    • Reyes Rojas, Montserrat; Flores Lillo, Tania; Betancur, Diego; Peña Oyarzún, Daniel; Torres Gómez, Vicente (MDPI, 2020)
      Oral carcinogenesis is a complex and multifactorial process that involves cumulative genetic and molecular alterations, leading to uncontrolled cell proliferation, impaired DNA repair and defective cell death. At the ...
    • Peña Oyarzún, Daniel; Rodríguez Peña, Marcelo; Burgos Bravo, Francesca; Vergara, Ángelo; Kretschmar Montecinos, Catalina; Sotomayor Flores, Cristián; Ramírez Sarmiento, César A.; De Smedt, Humbert; Reyes Rojas, Montserrat; Pérez, William; Torres Gómez, Vicente; Morselli, Eugenia; Altamirano, Francisco; Wilson, Christian; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Taylor & Francis, 2020)
      Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a ...
    • Brizuela, C.; Meza, G.; Mercadé, M.; Inostroza, C.; Chaparro, A.; Bravo, I.; Briceño, C.; Hernández, M.; Giner, L.; Ramírez, V. (Wiley, 2020)
      Aim To explore a set of inflammatory biomarkers obtained from dentinal fluid (DF) from patients with symptomatic irreversible pulpitis (IP), reversible pulpitis (RP) and normal pulp (NP). Methodology A cross-sectional ...
    • Suazo Sanhueza, José; Recabarren, Andrea S.; Marín, Nicolás R.; Blanco Castillo, Rafael (Springer, 2020)
      The aim of this study was to assess the association betweenIRF6single nucleotide polymorphisms and nonsyndromic cleft lip, with or without cleft palate (NSCL/P), in a Chilean population, based on a case-control sample and ...
    • Di Summa, Francesca; Kargarpour, Zahra; Nasirzade, Jila; Stähli, Alexandra; Mitulović, Goran; Panić Janković, Tanja; Koller, Veronika; Kaltenbach, Cosima; Müller, Heinz; Panahipour, Layla; Gruber, Reinhard; Strauss, Franz Josef (Nature, 2020)
      Platelet-rich fibrin (PRF) contains a broad spectrum of bioactive molecules that can trigger several cellular responses. However, these molecules along with their upstream responses remain mostly uninvestigated. By means ...
    • Strauss Avendaño, Franz; Stahli, Alexandra; Kobatake, Reiko; Tangl, Stefan; Heimel, Patrick; Alccayhuaman, Karol Ali Apaza; Schosserer, Markus; Hackl, Matthias; Grillari, Johannes; Gruber, Reinhard (Wiley, 2020)
      Objectives MicroRNAs (miRNAs) are small noncoding RNAs demonstrated as critical post-transcriptional modulators in dental tissues and bone regeneration, particularly miR-21-5p. However, the role of miR-21-5p in the healing ...
    • Muñoz, Pablo; Ardiles, Álvaro O.; Pérez Espinosa, Boris; Núñez Espinosa, Cristian; Paula Lima, Andrea; González Billault, Christian; Espinosa Parrilla, Yolanda (Elsevier, 2020)
      Aging is a natural process that includes several changes that gradually make organisms degenerate and die. Harman's theory proposes that aging is a consequence of the progressive accumulation of oxidative modifications ...
    • Lagos Tissie, Denisse; Bravo R., Lidia (Sociedad Médica Santiago, 2020)
      La mediación en el cuidado de la salud es un proceso no contencioso para resolver una disputa entre pacientes y proveedores de servicios de salud durante la atención médica Objetivo: Caracterizar el proceso de mediación ...