Author | dc.contributor.author | Da Silva, Jaqueline | |
Author | dc.contributor.author | Barría, Claudio | es_CL |
Author | dc.contributor.author | Jullian Matthaei, Carolina | es_CL |
Author | dc.contributor.author | Navarrete Encina, Patricio | es_CL |
Author | dc.contributor.author | Núñez Vergara, Luis | es_CL |
Author | dc.contributor.author | Squella Serrano, Juan | es_CL |
Admission date | dc.date.accessioned | 2007-05-18T15:04:54Z | |
Available date | dc.date.available | 2007-05-18T15:04:54Z | |
Publication date | dc.date.issued | 2005-01 | |
Cita de ítem | dc.identifier.citation | JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY 16 (1): 112-115 JAN-FEB 2005 | en |
Identifier | dc.identifier.issn | 0103-5053 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/120417 | |
Abstract | dc.description.abstract | 1,4-dihydropyridine derivatives constitute an important pharmacological group for the treatment of cardiovascular diseases. We have synthesised a series 4-(5'-nitro-2'-furyl)-1,4-dihydropyridine derivatives, which were characterised by H-1-NMR. We have found that carboethoxy groups at the C-3 and C-5 on the 1,4-dihydropyridine ring show a much more complex signal in the H-1 NMR spectra, either when C-4 is a pseudo-prochiral or a chiral centre. | en |
Lenguage | dc.language.iso | en | en |
Publisher | dc.publisher | SOC BRASILEIRA QUIMICA | en |
Keywords | dc.subject | HANTZSCH 1,4-DIHYDROPYRIDINES | en |
Título | dc.title | Unexpected diastereotopic behaviour in the H-1 NMR spectrum of 1,4-dihydropyridine derivatives triggered by chiral and prochiral centres | en |
Document type | dc.type | Artículo de revista | |