Author | dc.contributor.author | Navarrete Encina, Patricio | es_CL |
Author | dc.contributor.author | Squella Serrano, Juan | es_CL |
Author | dc.contributor.author | Carbajo, J. | |
Author | dc.contributor.author | Conde, B. | es_CL |
Author | dc.contributor.author | Núñez Vergara, Luis | es_CL |
Admission date | dc.date.accessioned | 2008-09-26T12:04:42Z | |
Available date | dc.date.available | 2008-09-26T12:04:42Z | |
Publication date | dc.date.issued | 2007 | |
Cita de ítem | dc.identifier.citation | SYNTHETIC COMMUNICATIONS 37(12):2051-2060 | en |
Identifier | dc.identifier.issn | 0039-7911 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/120505 | |
Abstract | dc.description.abstract | A series of C-3,4,5-substituted 2,6-dimethyl-1,4-dihydropyridines ( 1,4-DHPs) with pharmacological properties were prepared by a variation from the classical Hantzsch synthesis. The procedure involves treatment of the respective aldehyde with either ethyl-3-aminocrotonate or 3-aminocrotonitrile in anhydrous acetic acid at temperatures not exceeding 60 degrees C, thus minimizing by-product formation. The structures of title compounds were elucidated by H-1 NMR, C-13 NMR, FTIR, and elemental analysis. | en |
Lenguage | dc.language.iso | en | en |
Publisher | dc.publisher | TAYLOR & FRANCIS INC | en |
Keywords | dc.subject | Nitrogen heterocycles | en |
Título | dc.title | Synthesis of some C-3,4,5-substituted 2,6-dimethyl-1,4-dihydropyridines (4-DHPs) | en |
Document type | dc.type | Artículo de revista | |