Show simple item record

Authordc.contributor.authorOlea Azar, Claudio 
Authordc.contributor.authorCerecetto, Hugo es_CL
Authordc.contributor.authorGerpe, Alejandra es_CL
Authordc.contributor.authorGonzález, Mercedes es_CL
Authordc.contributor.authorArán, Vicente J. es_CL
Authordc.contributor.authorRigol Olsen, Carolina es_CL
Authordc.contributor.authorOpazo, Lucía es_CL
Admission datedc.date.accessioned2009-06-03T11:17:57Z
Available datedc.date.available2009-06-03T11:17:57Z
Publication datedc.date.issued2006-01
Cita de ítemdc.identifier.citationSPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY Volume: 63 Issue: 1 Pages: 36-42 Published: JAN 2006en
Identifierdc.identifier.issn1386-1425
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/120657
Abstractdc.description.abstractThe electrochemistry of 3-alkoxy- and 3-hydroxy-1-[(omega-(dialkylamino)alkyl]-5-nitroindazole derivatives were characterized using cyclic voltammetry in DMSO. The nitro reduction process was studied and this was affected by the acid moieties present in these compounds. A nitro anion self-protonation process was observed. This phenomenon was studied by cyclic voltammetry in presence of increasing amount of NaOH. The reactivity of the nitro anion radical of these derivatives with glutathione was also studied by cyclic voltammetry. The oxidizing effect of glutathione is supported by the parallel decrease of the anodic peak current and increase of the cathodic peak in the cyclic voltammograms, corresponding to the wave of the nitro anion radical from uncharged species with the addition of glutathione. Nitro anion radicals obtained by electrolytic reduction of these derivatives were measured and analyzed in DMSO using electron spin resonance spectroscopy.en
Lenguagedc.language.isoenen
Publisherdc.publisherPERGAMON-ELSEVIER SCIENCE LTDen
Keywordsdc.subjectSTATIONARY ELECTRODE POLAROGRAPHYen
Títulodc.titleESR and electrochemical study of 5-nitroindazole derivatives with antiprotozoal activityen
Document typedc.typeArtículo de revistaen


Files in this item

Icon

This item appears in the following Collection(s)

Show simple item record