| Author | dc.contributor.author | Ocaranza, María Paz | |
| Author | dc.contributor.author | Rivera, Paulina | es_CL |
| Author | dc.contributor.author | Novoa, Ulises | es_CL |
| Author | dc.contributor.author | Pinto, Melissa | es_CL |
| Author | dc.contributor.author | González, Leticia | es_CL |
| Author | dc.contributor.author | Chiong Lay, Mario | es_CL |
| Author | dc.contributor.author | Lavandero González, Sergio | es_CL |
| Author | dc.contributor.author | Jalil Milad, Jorge | es_CL |
| Admission date | dc.date.accessioned | 2011-08-08T13:34:12Z | |
| Available date | dc.date.available | 2011-08-08T13:34:12Z | |
| Publication date | dc.date.issued | 2011-04 | |
| Cita de ítem | dc.identifier.citation | JOURNAL OF HYPERTENSION 29 (4): 706-715 | es_CL |
| Identifier | dc.identifier.issn | 0263-6352 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/121576 | |
| General note | dc.description | Artículo de publicación ISI | es_CL |
| Abstract | dc.description.abstract | Background Angiotensin II (Ang II) levels depend on renin, angiotensin-converting enzyme (ACE), and on the homologous angiotensin-converting enzyme (ACE2). Increased ACE and Ang II levels are associated with higher Rho kinase activity. However, the relationship between Rho kinase activation and ACE2 in hypertension is unknown.
Objective The role of the Rho kinase signaling pathway in both enzymatic activity and aortic gene expression of ACE2 in deoxycorticosterone acetate (DOCA) hypertensive rats was assessed in the present study. | es_CL |
| Lenguage | dc.language.iso | en | es_CL |
| Publisher | dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | es_CL |
| Keywords | dc.subject | PULMONARY ARTERIAL-HYPERTENSION | es_CL |
| Título | dc.title | Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension | es_CL |
| Document type | dc.type | Artículo de revista | |
