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Authordc.contributor.authorBravo Sagua, Roberto
Authordc.contributor.authorTorrealba Cárdenas, Natalia Belénes_CL
Authordc.contributor.authorParedes, Felipees_CL
Authordc.contributor.authorMorales, Pablo E.es_CL
Authordc.contributor.authorPennanen Saavedra, Christianes_CL
Authordc.contributor.authorLópez Crisosto, Camilaes_CL
Authordc.contributor.authorTroncoso Cotal, Rodrigoes_CL
Authordc.contributor.authorCriollo Céspedes, Alfredoes_CL
Authordc.contributor.authorChiong Lay, Marioes_CL
Authordc.contributor.authorHill, Joseph A.es_CL
Authordc.contributor.authorSimmend, Thomases_CL
Authordc.contributor.authorQuest, Andrew F. G.es_CL
Authordc.contributor.authorLavandero González, Sergioes_CL
Cita de ítemdc.identifier.citationThe International Journal of Biochemistry & Cell Biology 50 (2014) 55–59en_US
Abstractdc.description.abstractCellular organelles do not function as isolated or static units, but rather form dynamic contacts between one another that can be modulated according to cellular needs. The physical interfaces between organelles are important for Ca2+ and lipid homeostasis, and serve as platforms for the control of many essential functions including metabolism, signaling, organelle integrity and execution of the apoptotic program. Emerging evidence also highlights the importance of organelle communication in disorders such as Alzheimer’s disease, pulmonary arterial hypertension, cancer, skeletal and cardiac muscle dysfunction. Here, we provide an overview of the current literature on organelle communication and the link to human pathologies.en_US
Patrocinadordc.description.sponsorshipThis work was funded by Comision Nacional de Ciencia y Tec-nologia (CONICYT), Chile: FONDECYT 1120212 to SL, 11130285 to RT, 3130749 to CP; Anillo ACT1111 to SL, AQ & MC; FONDAP15130011 to SL, AQ, MC & JAH; JAH; Red Internacional 120003 toSL, AQ, JAH; by the National Institutes of Health (HL-075173, to JAH;HL-080144, to JAH; HL-090842, to JAH), American Heart Associa-tion (0640084N, to JAH, 7-08-MN-21-ADA, to JAH), and the AHA-JonHolden DeHaan Foundation (0970518N, to JAH); Natural Sciencesand Engineering Research Council [grant number 386757-2010] toTS; and CONICYT PhD fellowships to RB, NT, CLC and FP and PewCharitable Trust Postdoctoral Fellowship to AC.en_US
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.uri*
Títulodc.titleOrganelle communication: Signaling crossroads between homeostasis and diseaseen_US
Document typedc.typeArtículo de revista
dcterms.accessRightsdcterms.accessRightsAcceso abierto
Indexationuchile.indexArtículo de publicación SCOPUS
Indexationuchile.indexArtículo de publicación WoS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile