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Authordc.contributor.authorMartínez García, Laura 
Authordc.contributor.authorSanabria, Andrea Juliana es_CL
Authordc.contributor.authorAraya Cabello, Ignacio es_CL
Authordc.contributor.authorLawson, Jennifer es_CL
Authordc.contributor.authorHaynes, R. Brian es_CL
Authordc.contributor.authorRigau, David es_CL
Authordc.contributor.authorSolà, Iván es_CL
Authordc.contributor.authorDíaz del Campo, Patra es_CL
Authordc.contributor.authorEstrada, Maria Dolors es_CL
Authordc.contributor.authorEtxeandia Ikobaltzeta, Itziar es_CL
Authordc.contributor.authorGarcía Álvarez, Elvira es_CL
Authordc.contributor.authorGracia, Javier es_CL
Authordc.contributor.authorKotzeva, Anna es_CL
Authordc.contributor.authorLouro González, Arturo es_CL
Authordc.contributor.authorSalcedo Fernandez, Flavia es_CL
Authordc.contributor.authorTrujillo Martín, María Mar es_CL
Authordc.contributor.authorAlonso Coello, Pablo es_CL
Admission datedc.date.accessioned2014-02-12T20:41:56Z
Available datedc.date.available2014-02-12T20:41:56Z
Publication datedc.date.issued2013
Cita de ítemdc.identifier.citationMartínez García et al. Implementation Science 2013, 8:94en_US
Identifierdc.identifier.otherdoi:10.1186/1748-5908-8-94
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/123525
General notedc.descriptionArtículo de publicación ISIen_US
Abstractdc.description.abstractBackground: Clinical practice guidelines (CPGs) become quickly outdated and require a periodic reassessment of evidence research to maintain their validity. However, there is little research about this topic. Our project will provide evidence for some of the most pressing questions in this field: 1) what is the average time for recommendations to become out of date?; 2) what is the comparative performance of two restricted search strategies to evaluate the need to update recommendations?; and 3) what is the feasibility of a more regular monitoring and updating strategy compared to usual practice?. In this protocol we will focus on questions one and two. Methods: The CPG Development Programme of the Spanish Ministry of Health developed 14 CPGs between 2008 and 2009. We will stratify guidelines by topic and by publication year, and include one CPG by strata. We will develop a strategy to assess the validity of CPG recommendations, which includes a baseline survey of clinical experts, an update of the original exhaustive literature searches, the identification of key references (reference that trigger a potential recommendation update), and the assessment of the potential changes in each recommendation. We will run two alternative search strategies to efficiently identify important new evidence: 1) PLUS search based in McMaster Premium LiteratUre Service (PLUS) database; and 2) a Restrictive Search (ReSe) based on the least number of MeSH terms and free text words needed to locate all the references of each original recommendation. We will perform a survival analysis of recommendations using the Kaplan-Meier method and we will use the log-rank test to analyse differences between survival curves according to the topic, the purpose, the strength of recommendations and the turnover. We will retrieve key references from the exhaustive search and evaluate their presence in the PLUS and ReSe search results. Discussion: Our project, using a highly structured and transparent methodology, will provide guidance of when recommendations are likely to be at risk of being out of date. We will also assess two novel restrictive search strategies which could reduce the workload without compromising rigour when CPGs developers check for the need of updating.en_US
Lenguagedc.language.isoenen_US
Publisherdc.publisherBioMed Centralen_US
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Keywordsdc.subjectClinical practice guidelinesen_US
Títulodc.titleStrategies to assess the validity of recommendations: a study protocolen_US
Document typedc.typeArtículo de revista


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile