Estudio de correlación clínico-radiológica, sensibilidad y especificidad de ecotomografía transcraneana en enfermedad de Parkinson y otros trastornos del movimiento

Abstract

Background: The detection of hyperechogenicity of the substantia nigra using trans cranial sonography can be predictive of the diagnosis of Parkinson Disease. Aim: To report an experience with transcranial sonography for the diagnosis of Parkinson disease. Material and Methods: One hundred sixteen patients with movement disorders were subjected to a transcranial sonograpy to detect the presence of hyperchogenicity of the substantia nigra and basal ganglia. Afterwards, two physicians, unaware of the results of the sonography, examined the patients and reached a clinical diagnosis. The concordance between ultrasound results and the clinical diagnosis was analyzed. Results: In 64 patients, a clinical diagnosis of Parkinson disease was reached. Of these, 52 patients had substantia nigra hyperechogenicity and in 12, it was normal. On the other hand ultrasound was normal in 42 of 43 patients without a clinical diagnosis of Parkinson disease. Therefore the sensitivity and specifi city of trans cranial ultrasound for the diagnosis of Parkinson disease was 81 and 97%, respectively. Conclusions: Transcranial sonography has a good sensitivity and specifi city for the diagnosis of Parkinson disease.