Author | dc.contributor.author | Tsuchiya, Yasuo | es_CL |
Author | dc.contributor.author | Serra Canales, Iván | es_CL |
Author | dc.contributor.author | Hori, Yasushi | es_CL |
Author | dc.contributor.author | Calvo, Alfonso | es_CL |
Author | dc.contributor.author | Villegas Ríos, Rodrigo Luis | es_CL |
Author | dc.contributor.author | Shibuya, Norio | es_CL |
Author | dc.contributor.author | Nakamura, Kazutoshi | |
Author | dc.contributor.author | Yamamoto, Masaharu | es_CL |
Admission date | dc.date.accessioned | 2009-05-12T17:41:01Z | |
Available date | dc.date.available | 2009-05-12T17:41:01Z | |
Publication date | dc.date.issued | 2006-04 | |
Cita de ítem | dc.identifier.citation | Volume 39, Issue 4, April 2006, Pages 410-413 | en |
Identifier | dc.identifier.issn | ISSN: 0009-9120 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/127827 | |
Abstract | dc.description.abstract | Objectives: To evaluate the association between gallstones and biliary free fatty acids (FFAs) as the first attempt to clarify whether biliary
FFAs relate to developing gallbladder cancer (GBC) in Chile, which has the highest mortality rate in the world.
Design and methods: Gallbladder bile from 21 male and 129 female patients with gallstones from Santiago was collected, and their FFAs
were measured. The results were compared with those observed in a similar previous study performed in Niigata and Kochi Prefectures which
showed the highest and lowest mortality rates, respectively, for GBC in Japan.
Results: Palmitoleic and linolenic acids compositions in Santiago patients were significantly lower than those in Niigata and Kochi patients,
though these compositions in Niigata patients were significantly lower than those in Kochi patients. The levels of these FFAs compositions
decreased in the order of Kochi, Niigata, and Santiago patients.
Conclusions: Decreased biliary FFAs compositions may relate to developing gallstones and subsequently GBC. | en |
Lenguage | dc.language.iso | en | en |
Publisher | dc.publisher | Clinical Biochemistry | en |
Keywords | dc.subject | Cholelithiasis | en |
Título | dc.title | Free fatty acid concentrations in gallbladder bile collected from Chilean patients with gallstones | en |
Document type | dc.type | Artículo de revista | |