| Author | dc.contributor.author | Paez, Maria Carolina | es_CL |
| Author | dc.contributor.author | González Burgos, María Julieta | es_CL |
| Author | dc.contributor.author | Serrano, Norma C. | es_CL |
| Author | dc.contributor.author | Shoenfeld, Yehuda | |
| Author | dc.contributor.author | Anaya, Juan Manuel | es_CL |
| Admission date | dc.date.accessioned | 2009-06-24T11:03:50Z | |
| Available date | dc.date.available | 2009-06-24T11:03:50Z | |
| Publication date | dc.date.issued | 2007-03 | |
| Cita de ítem | dc.identifier.citation | AUTOIMMUNITY, V.: 40, issue: 2, p.: 83-94, MAR 2007. | en |
| Identifier | dc.identifier.issn | 0891-6934 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/128015 | |
| Abstract | dc.description.abstract | The extracellular matrix plays an important role in modulating the behavior of cells with which it interacts. There are a
number of families of extracellular matrix (ECM) proteins including collagens, proteoglycans and laminins (LM). LM are the
major component of the basal lamina (BL). Here, we review the current knowledge on their structure, self-assembly, binding
mechanisms, diverse tissue-expression patterns and its impact on pathology. Studies and hypothesis exploring the role of LM
and their polymorphic genes on autoimmune diseases (AIDs) such as systemic lupus erythematosus and Sjo¨gren’s syndrome
(SS) are also discussed. | en |
| Patrocinador | dc.description.sponsorship | This work was supported by Fundación para la
Promoción de la Investigación y Tecnología, Bogotá
(MCP, J-MA), Universidad Autónoma de Bucaramanga
(MCP, NCS), Colombia and Fondecyt,
1050192, Chile (MJG). | |
| Lenguage | dc.language.iso | en | en |
| Publisher | dc.publisher | TAYLOR & FRANCIS LTD | en |
| Keywords | dc.subject | Laminin | en |
| Título | dc.title | Physiological and pathological implications of laminins: From the gene to the protein | en |
| Document type | dc.type | Artículo de revista | |
