| Author | dc.contributor.author | Oliva, Carlos | |
| Author | dc.contributor.author | Escobedo, Pía | es_CL |
| Author | dc.contributor.author | Astorga, César | es_CL |
| Author | dc.contributor.author | Molina, Claudia | es_CL |
| Author | dc.contributor.author | Sierralta Jara, Jimena | es_CL |
| Admission date | dc.date.accessioned | 2012-06-21T20:58:35Z | |
| Available date | dc.date.available | 2012-06-21T20:58:35Z | |
| Publication date | dc.date.issued | 2012-01 | |
| Cita de ítem | dc.identifier.citation | DEVELOPMENTAL NEUROBIOLOGY Volume: 72 Issue: 1 Special Issue: SI Pages: 57-72 Published: JAN 2012 | es_CL |
| Identifier | dc.identifier.other | DOI 10.1002/dneu.20949 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/128982 | |
| General note | dc.description | Artículo de publicación ISI | es_CL |
| Abstract | dc.description.abstract | Synaptic function is crucially dependent
on the spatial organization of the presynaptic and
postsynaptic apparatuses and the juxtaposition of both
membrane compartments. This precise arrangement is
achieved by a protein network at the submembrane
region of each cell that is built around scaffold proteins.
The membrane-associated guanylate kinase (MAGUK)
family of proteins is a widely expressed and well-conserved
group of proteins that plays an essential role in
the formation and regulation of this scaffolding. Here,
we review general features of this protein family, focusing
on the discs large and calcium/calmodulin-dependent
serine protein kinase subfamilies of MAGUKs in the formation,
function, and plasticity of synapses. | es_CL |
| Patrocinador | dc.description.sponsorship | ICM
P07-048-F
CONICYT
FONDECYT
1090272 | es_CL |
| Lenguage | dc.language.iso | en | es_CL |
| Publisher | dc.publisher | WILEY-BLACKWELL | es_CL |
| Keywords | dc.subject | MAGUK | es_CL |
| Título | dc.title | Role of the MAGUK Protein Family in Synapse Formation and Function | es_CL |
| Document type | dc.type | Artículo de revista | |
