Óxido nítrico exhalado, asma y atopia: análisis en un panel de niños en Santiago, Chile
Author
dc.contributor.author
Vidal, Daniela
Author
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Yohannessen, Karla
es_CL
Author
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Prieto, Laura
es_CL
Author
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Ubilla Pérez, Carlos
es_CL
Author
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Ruíz, Pablo A.
es_CL
Admission date
dc.date.accessioned
2014-03-06T20:08:25Z
Available date
dc.date.available
2014-03-06T20:08:25Z
Publication date
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2013
Cita de ítem
dc.identifier.citation
r ev Med Cchile 2013; 141: 743-750
en_US
Identifier
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https://repositorio.uchile.cl/handle/2250/129287
General note
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Artículo de publicación ISI
en_US
Abstract
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Background: Chronic airway inflammation is a central process in asthma. Measurement
of exhaled nitric oxide (eNO) is a non-invasive biomarker of eosinophilic airway inflammation. Aim: To measure eNO levels in a population of asthmatic and non-asthmatic children and to evaluate their relationship with asthma and atopy. Material and Methods: We studied 143 asthmatic and non-asthmatic children aged 6 to 14 years attended a hospital and primary health service. Participants were tested for allergies and followed during the winter months of 2010 and 2011. They were visited regularly at their homes and eNO levels were measured on each visit using a handheld equipment. Mean eNO distribution were compared by the presence of asthma or atopy using t-test and regression models. Results: No significant differences for mean eNO levels were detected, according to presence of asthma or atopy, by any of the statistical methods used. Regression models showed significant effects for age but not for sex. Conclusions: There were no differences in eNO levels in the studied children by the presence of asthma or atopy.