ATP signaling in skeletal muscle: from fiber plasticity to regulation of metabolism
| Author | dc.contributor.author | Casas Atala, Mariana | es_CL |
| Author | dc.contributor.author | Buvinic Radic, Sonja | |
| Author | dc.contributor.author | Jaimovich Pérez, Enrique | es_CL |
| Admission date | dc.date.accessioned | 2014-12-12T13:56:08Z | |
| Available date | dc.date.available | 2014-12-12T13:56:08Z | |
| Publication date | dc.date.issued | 2014 | |
| Cita de ítem | dc.identifier.citation | ATP Signaling in Skeletal Muscle Volume 42 & Number 3 & July 2014 | en_US |
| Identifier | dc.identifier.issn | 0091-6331 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/129360 | |
| General note | dc.description | Artículo de publicación ISI | en_US |
| Abstract | dc.description.abstract | Tetanic electrical stimulation releases adenosine triphosphate (ATP) from muscle fibers through pannexin-1 channels in a frequency-dependent manner; extracellular ATP activates signals that ultimately regulate gene expression and is able to increase glucose transport through activation of P2Y receptors, phosphatidylinositol 3-kinase, Akt, and AS160. We hypothesize that this mechanism is an important link between exercise and the regulation of muscle fiber plasticity and metabolism. | en_US |
| Patrocinador | dc.description.sponsorship | This work was financed by CONICYT ACT 1111 (E. Jaimovich, M. Casas, S. Buvinic), FONDECYT no. 1110467 (E. Jaimovich, S. Buvinic, M. Casas), 11100454 (S. Buvinic), and U-INICIA VID 2011, U-INICIA 02/12M; University of Chile (M. Casas). | en_US |
| Lenguage | dc.language.iso | en | en_US |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | * |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | * |
| Keywords | dc.subject | Gene expression | en_US |
| Título | dc.title | ATP signaling in skeletal muscle: from fiber plasticity to regulation of metabolism | en_US |
| Document type | dc.type | Artículo de revista |
Files in this item
This item appears in the following Collection(s)
-
Artículos de revistas
Artículos de revistas
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile